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Anterior Cingulate Cortex and the Medial Pain System

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Neurobiology of Cingulate Cortex and Limbic Thalamus

Abstract

The processing of sensory afferents in the cerebral cortex involves divergent processing of components of each sensory space. In the visual system, for example, there are separate and sequential, corticocortical projections for the analysis of form, color, movement, and depth (DeYoe and Van Essen, 1988; Livingstone and Hubel, 1988; Zeki and Shipp, 1988). A divergence of functional processing of different features of noci-ceptor-evoked activity may also occur in the cerebral cortex. Thus, there is a long history for dividing the pain system into two theoretical components: one involved in localization and sensory discrimination and the other involved in affective responses to noxious stimuli (e.g., Melzack and Casey, 1968; Melzack, 1975; Kenshalo and Willis, 1991).

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Vogt, B.A., Sikes, R.W., Vogt, L.J. (1993). Anterior Cingulate Cortex and the Medial Pain System. In: Vogt, B.A., Gabriel, M. (eds) Neurobiology of Cingulate Cortex and Limbic Thalamus. Birkhäuser, Boston, MA. https://doi.org/10.1007/978-1-4899-6704-6_11

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