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Eyelid and Periocular Skin Tumors

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Orbital Tumors

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Abstract

Malignant skin neoplasias commonly affect the eyelids and periocular region, particularly in high UV exposure zones. Secondary orbital invasion is a serious and potentially fatal complication of cutaneous tumors. The most frequent skin tumors resulting in orbital invasion are basal cell carcinoma, squamous cell carcinoma, sebaceous gland carcinoma, and malignant melanomas. Orbital invasion from eyelid tumors usually results from a delayed presentation/diagnosis, incomplete treatment with subsequent recurrences, and highly aggressive invasive tumors.

This chapter reviews the morphologic features and clinical manifestations of basal cell carcinoma, squamous cell carcinoma, keratoacanthoma, sebaceous gland carcinoma, and melanoma which develop in the periorbital area. The surgical and radiation management of each entity is also reviewed and the prognostic traits are discussed. It is emphasized that when these tumors occur in immunosuppressed patients and in individuals with HIV/AIDS, not only do they present at a younger age, but their clinical behaviors differ from the norm and may become very aggressive.

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Authors and Affiliations

  1. Department of Ophthalmology, University of Virginia Health System, Charlottesville, VA, 22903, USA

    Maria Kirzhner M.D.

  2. Departments of Ophthalmology and Pathology and Emily Couric Cancer Center, University of Virginia Health System, 1300 Jefferson Park Avenue, Charlottesville, VA, 22903, USA

    Zeynel A. Karcioglu M.D.

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Correspondence to Maria Kirzhner M.D. .

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  1. Department of Ophthalmology, University of Virginia, Charlottesville, Virginia, USA

    Zeynel A. Karcioglu

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Kirzhner, M., Karcioglu, Z.A. (2015). Eyelid and Periocular Skin Tumors. In: Karcioglu, Z. (eds) Orbital Tumors. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1510-1_20

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