Abstract
This chapter outlines an interaction between sleep and epilepsy including effect of sleep on epilepsy, epilepsy on sleep, and antiepileptic medication on sleep, preceded by a brief discussion about mechanism of epilepsy and sleep. We also mention about the impact of autonomic nervous system and sleep apnea in epilepsy. Finally, we discuss about special seizure types occurring during night as well as diagnostic procedures and practical relevance to understanding the relationship between sleep and epilepsy.
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309636_4_En_44_MOESM1_ESM.mp4
Supplementary material 1: A 34 years old woman with pharmacoresistant Nocturnal Frontal Lobe Epilepsy originating from the left cingulate gyrus. The first part documents a paroxysmal arousal characterized by a sudden elevation of the trunk (the patient assumes the sitting position). In the second part, a seizure characterized by hyperkinetic automatisms (pelvic thrusting and thrashing – copulatory automatisms) is documented; immediately at the end of the seizure the patient was able to correctly understand, answer and execute the command requested by the technician (to grab her hand) (MP4 1749 kb)
309636_4_En_44_MOESM2_ESM.mp4
Supplementary material 2: A 36 years old man with pharmacoresistant Nocturnal Frontal Lobe Epilepsy originating from the right supplementary motor area. The seizure is characterized by the assumption of an asymmetric tonic-dystonic posture without any alteration of consciousness. During the seizure the patient could not speak. Immediately at the end he was able to answer correctly to the previous question of the technician who asked “How many fingers are these?”, while showing three fingers (MP4 1289 kb)
309636_4_En_44_MOESM3_ESM.mp4
Supplementary material 3: A 24 years old man with pharmacoresistant Nocturnal Frontal Lobe Epilepsy with a right frontal antero-mesial onset. The seizure is characterized by body rotation, pelvic thrusting, thrashing and moaning. At the end of the episode the patient is immediately able to speak and to remember what it was said to him during the seizure (MP4 3469 kb)
309636_4_En_44_MOESM4_ESM.mp4
Supplementary material 4: A 38 years old man with pharmacoresistant episodes of Epileptic Nocturnal Wandering. The seizure is characterized by fear, screaming, pelvic thrusting, body rotation and wandering. The investigation with intracerebral recordings demonstrated an origin from the right temporal lobe structures (amygdala, hippocampus, para-hippocampus, and temporal pole); the hyper-kinetic phase and the episode of wandering appeared when the discharge involved the cingulated gyrus (see ref. 263) (MP4 2802 kb)
309636_4_En_44_MOESM5_ESM.mp4
Supplementary material 5: A 22 years old woman with pharmacoresistant sleep-related seizures originating from the right insulo-opercular region. Seizures are characterized by tonic-dystonic posturing (prevailing on the left side), hypersalivation, right tonic deviation of the mouth (MP4 2523 kb)
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Chokroverty, S., Nobili, L. (2017). Sleep and Epilepsy. In: Chokroverty, S. (eds) Sleep Disorders Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-6578-6_44
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