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Molecular Pathology in Cancer Research

  • Book
  • © 2016

Overview

  • Discusses the germline and somatic mutations that are present in different cancers

  • Provides new insights on the abnormalities of structure and function of tumors at the cellular, tissue and organ level

  • Examines the refinement of current classifications of different tumors and the identification of novel predictive and prognostic biomarkers

  • Includes supplementary material: sn.pub/extras

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Table of contents (16 chapters)

Keywords

About this book

The aim of the book is to discuss the application of molecular pathology in cancer research, and its contribution in the classification of different tumors and identification of potential molecular targets, as well as how this knowledge may be translated into clinical practice, and the huge impact this field is likely to have in the next 5 to 10 years.

Editors and Affiliations

  • UQ Centre for Clinical Research, The Royal Brisbane and Women’s Hospital, University of Queensland and Pathology Queensland, Brisbane, Australia

    Sunil R. Lakhani

  • Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, Australia

    Stephen B. Fox

About the editors

Sunil Lakhani is State Director, Anatomical Pathology, Pathology Queensland, Professor and Head, Molecular & Cellular Pathology, The School of Medicine, and Head of the Breast Group, The University of Queensland Centre for Clinical Research (UQCCR). His research team comprises scientists and practicing clinicians ensuring a translational focus to the research portfolio. His current research interests include lobular carcinoma and its variants, tumours with a basal phenotype and mechanisms of brain and distant metastases. He is a series editor for the WHO Tumour Classification Books and volume editor for the WHO Classification Tumours of the Breast (4th Ed 2012).




Stephen Fox is Director of Pathology at the Peter MacCallum Cancer Centre, Professorial Fellow at the University of Melbourne and an NH&MRC Practitioner Fellow. His research has primarily been aimed at understanding the molecular basis of cancer, with emphasis on prognosis and predictive markers of human tumours with more recent work focusing on developing and implementing clinical grade diagnostics, particularly in sequencing to match the new paradigm of personalised medicine.

Bibliographic Information

  • Book Title: Molecular Pathology in Cancer Research

  • Editors: Sunil R. Lakhani, Stephen B. Fox

  • DOI: https://doi.org/10.1007/978-1-4939-6643-1

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media LLC 2016

  • Hardcover ISBN: 978-1-4939-6641-7Published: 29 January 2017

  • Softcover ISBN: 978-1-4939-8258-5Published: 15 July 2018

  • eBook ISBN: 978-1-4939-6643-1Published: 20 January 2017

  • Edition Number: 1

  • Number of Pages: VIII, 369

  • Number of Illustrations: 20 b/w illustrations, 39 illustrations in colour

  • Topics: Cancer Research, Human Genetics, Cell Biology, Proteomics, Gene Expression

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