Skip to main content

Diagnostic Imaging: Ultrasound

  • Protocol
  • First Online:
Book cover Preeclampsia

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1710))

  • 2767 Accesses

Abstract

Diagnostic ultrasound imaging, particularly that which includes pulsed wave Doppler interrogation, is a safe, real-time modality by which the risk of developing preeclampsia can be refined, and the effects of established disease can be assessed. This chapter outlines the rationale and technique for Doppler interrogation of the maternal ophthalmic and uterine arteries and grayscale imaging of the maternal optic nerve sheath diameter.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

References

  1. Zeeman GG (2009) Neurologic complications of pre-eclampsia. Semin Perinatol 33(3):166–172. https://doi.org/10.1053/j.semperi.2009.02.003

    Article  PubMed  Google Scholar 

  2. Altman D, Carroli G, Duley L, Farrell B, Moodley J, Neilson J, Smith D (2002) Do women with pre-eclampsia, and their babies, benefit from magnesium sulphate? The Magpie Trial: a randomised placebo-controlled trial. Lancet 359(9321):1877–1890

    Article  Google Scholar 

  3. Crovetto F, Somigliana E, Peguero A, Figueras F (2013) Stroke during pregnancy and pre-eclampsia. Curr Opin Obstet Gynecol 25(6):425–432. https://doi.org/10.1097/gco.0000000000000024

    Article  PubMed  Google Scholar 

  4. Kane SC, Dennis A, da Silva Costa F, Kornman L,Brennecke SP (2013) Contemporary clinical management of the cerebral complications of preeclampsia. Obstet Gynecol Int 2013:985606. https://doi.org/10.1155/2013/985606

    Article  PubMed  PubMed Central  Google Scholar 

  5. Dubourg J, Javouhey E, Geeraerts T, Messerer M, Kassai B (2011) Ultrasonography of optic nerve sheath diameter for detection of raised intracranial pressure: a systematic review and meta-analysis. Intensive Care Med 37(7):1059–1068. https://doi.org/10.1007/s00134-011-2224-2

    Article  PubMed  Google Scholar 

  6. Diniz AL, Moron AF, dos Santos MC, Sass N, Pires CR, Debs CL (2008) Ophthalmic artery Doppler as a measure of severe pre-eclampsia. Int J Gynaecol Obstet 100(3):216–220. https://doi.org/10.1016/j.ijgo.2007.07.013

    Article  CAS  PubMed  Google Scholar 

  7. Carneiro RS, Sass N, Diniz AL, Souza EV, Torloni MR, Moron AF (2008) Ophthalmic artery Doppler velocimetry in healthy pregnancy. Int J Gynaecol Obstet 100(3):211–215. https://doi.org/10.1016/j.ijgo.2007.09.028

    Article  PubMed  Google Scholar 

  8. de Oliveira CA, de Sa RA, Velarde LG, Marchiori E, Netto HC, Ville Y (2009) Doppler velocimetry of the ophthalmic artery in normal pregnancy: reference values. J Ultrasound Med 28(5):563–569

    Article  Google Scholar 

  9. Kane SC, Brennecke SP, da Silva CF (2016) Ophthalmic artery Doppler analysis: a window into the cerebrovasculature of women with pre-eclampsia. Ultrasound Obstet Gynecol. https://doi.org/10.1002/uog.17209

  10. Campbell S, Bewley S, Cohen-Overbeek T (1987) Investigation of the uteroplacental circulation by Doppler ultrasound. Semin Perinatol 11(4):362–368

    CAS  PubMed  Google Scholar 

  11. Sciscione AC, Hayes EJ (2009) Uterine artery Doppler flow studies in obstetric practice. Am J Obstet Gynecol 201(2):121–126. https://doi.org/10.1016/j.ajog.2009.03.027

    Article  PubMed  Google Scholar 

  12. Schulman H, Fleischer A, Farmakides G, Bracero L, Rochelson B, Grunfeld L (1986) Development of uterine artery compliance in pregnancy as detected by Doppler ultrasound. Am J Obstet Gynecol 155(5):1031–1036

    Article  CAS  Google Scholar 

  13. Alves JA, Silva BY, de Sousa PC, Maia SB, Costa Fda S (2013) Reference range of uterine artery Doppler parameters between the 11th and 14th pregnancy weeks in a population sample from Northeast Brazil. Rev Bras Ginecol Obstet 35(8):357–362

    Article  Google Scholar 

  14. Gómez O, Figueras F, Fernández S, Bennasar M, Martínez JM, Puerto B, Gratacós E (2008) Reference ranges for uterine artery mean pulsatility index at 11-4 1 weeks of gestation. Ultrasound Obstet Gynecol 32(2):128–132. https://doi.org/10.1002/uog.5315

    Article  PubMed  Google Scholar 

  15. Lefebvre J, Demers S, Bujold E, Nicolaides KH, Girard M, Brassard N, Audibert F (2012) Comparison of two different sites of measurement for transabdominal uterine artery Doppler velocimetry at 11-13 weeks. Ultrasound Obstet Gynecol 40(3):288–292. https://doi.org/10.1002/uog.11137

    Article  CAS  PubMed  Google Scholar 

  16. Plasencia W, Barber MA, Alvarez EE, Segura J, Valle L, Garcia-Hernandez JA (2011) Comparative study of transabdominal and transvaginal uterine artery Doppler pulsatility indices at 11-13 + 6 weeks. Hypertens Pregnancy 30(4):414–420. https://doi.org/10.3109/10641955.2010.506232

    Article  PubMed  Google Scholar 

  17. Ridding G, Schluter PJ, Hyett JA, McLennan AC (2014) Uterine artery pulsatility index assessment at 11-13 weeks’ gestation. Fetal Diagn Ther 36(4):299–304. https://doi.org/10.1159/000361021

    Article  PubMed  Google Scholar 

  18. ter Haar G (2010) The new British Medical Ultrasound Society Guidelines for the safe use of diagnostic ultrasound equipment. Ultrasound 18(2):50–51. https://doi.org/10.1258/ult.2010.100007

    Article  Google Scholar 

  19. Erickson SJ, Hendrix LE, Massaro BM, Harris GJ, Lewandowski MF, Foley WD, Lawson TL (1989) Color Doppler flow imaging of the normal and abnormal orbit. Radiology 173(2):511–516. https://doi.org/10.1148/radiology.173.2.2678264

    Article  CAS  PubMed  Google Scholar 

  20. Correa-Silva EP, Surita FG, Barbieri C, Morais SS, Cecatti JG (2012) Reference values for Doppler velocimetry of the ophthalmic and central retinal arteries in low-risk pregnancy. Int J Gynaecol Obstet 117(3):251–256. https://doi.org/10.1016/j.ijgo.2012.01.012

    Article  PubMed  Google Scholar 

  21. Blaivas M, Theodoro D, Sierzenski PR (2002) A study of bedside ocular ultrasonography in the emergency department. Acad Emerg Med 9(8):791–799

    Article  Google Scholar 

  22. Blaivas M, Theodoro D, Sierzenski PR (2003) Elevated intracranial pressure detected by bedside emergency ultrasonography of the optic nerve sheath. Acad Emerg Med 10(4):376–381

    Article  Google Scholar 

  23. Rizzo G, Arduini D, Romanini C (1993) Uterine artery Doppler velocity waveforms in twin pregnancies. Obstet Gynecol 82(6):978–983

    CAS  PubMed  Google Scholar 

  24. Yu CK, Papageorghiou AT, Boli A, Cacho AM, Nicolaides KH (2002) Screening for pre-eclampsia and fetal growth restriction in twin pregnancies at 23 weeks of gestation by transvaginal uterine artery Doppler. Ultrasound Obstet Gynecol 20(6):535–540. https://doi.org/10.1046/j.1469-0705.2002.00865.x

    Article  CAS  PubMed  Google Scholar 

  25. Stampalija T, Gyte GM, Alfirevic Z (2010) Utero-placental Doppler ultrasound for improving pregnancy outcome. Cochrane Database Syst Rev (9):CD008363. https://doi.org/10.1002/14651858.CD008363.pub2

  26. Velauthar L, Plana MN, Kalidindi M, Zamora J, Thilaganathan B, Illanes SE, Khan KS, Aquilina J, Thangaratinam S (2014) First-trimester uterine artery Doppler and adverse pregnancy outcome: a meta-analysis involving 55,974 women. Ultrasound Obstet Gynecol 43(5):500–507. https://doi.org/10.1002/uog.13275

    Article  CAS  PubMed  Google Scholar 

  27. Cnossen JS, Morris RK, ter Riet G, Mol BWJ, van der Post JAM, Coomarasamy A, Zwinderman AH, Robson SC, Bindels PJE, Kleijnen J, Khan KS (2008) Use of uterine artery Doppler ultrasonography to predict pre-eclampsia and intrauterine growth restriction: a systematic review and bivariable meta-analysis. Can Med Assoc J 178(6):701–711. https://doi.org/10.1503/cmaj.070430

    Article  Google Scholar 

  28. Kane SC, da Silva Costa F, Brennecke SP (2014) New directions in the prediction of pre-eclampsia. Aust N Z J Obstet Gynaecol 54(2):101–107. https://doi.org/10.1111/ajo.12151

    Article  PubMed  Google Scholar 

  29. Poon LC, Kametas NA, Maiz N, Akolekar R, Nicolaides KH (2009) First-trimester prediction of hypertensive disorders in pregnancy. Hypertension 53(5):812–818. https://doi.org/10.1161/hypertensionaha.108.127977

    Article  CAS  PubMed  Google Scholar 

  30. Bhide A, Acharya G, Bilardo CM, Brezinka C, Cafici D, Hernandez-Andrade E, Kalache K, Kingdom J, Kiserud T, Lee W, Lees C, Leung KY, Malinger G, Mari G, Prefumo F, Sepulveda W, Trudinger B (2013) ISUOG practice guidelines: use of Doppler ultrasonography in obstetrics. Ultrasound Obstet Gynecol 41(2):233–239. https://doi.org/10.1002/uog.12371

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Fabricio da Silva Costa .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer Science+Business Media LLC

About this protocol

Check for updates. Verify currency and authenticity via CrossMark

Cite this protocol

Kane, S.C., Khong, S.L., da Silva Costa, F. (2018). Diagnostic Imaging: Ultrasound. In: Murthi, P., Vaillancourt, C. (eds) Preeclampsia . Methods in Molecular Biology, vol 1710. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7498-6_1

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-7498-6_1

  • Published:

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7497-9

  • Online ISBN: 978-1-4939-7498-6

  • eBook Packages: Springer Protocols

Publish with us

Policies and ethics