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Activated Partial Thromboplastin Time

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Book cover Haemostasis

Part of the book series: Methods in Molecular Biology ((MIMB,volume 992))

Abstract

Activated partial thromboplastin time (APTT) is a commonly used coagulation assay that is easy to perform, is affordable, and is therefore performed in most coagulation laboratories, both clinical and research, worldwide. The APTT is based on the principle that in citrated plasma, the addition of a platelet substitute, factor XII activator, and CaCl2 allows for formation of a stable clot. The time required for the formation of a stable clot is recorded in seconds and represents the actual APTT result.

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Author information

Authors and Affiliations

  1. Haematology Research Laboratory, Murdoch Childrens Research Institute, Melbourne, Australia

    Vera Ignjatovic

  2. Department of Paediatrics, The University of Melbourne, Melbourne, Australia

    Vera Ignjatovic

Authors
  1. Vera Ignjatovic
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Editor information

Editors and Affiliations

  1. Department of Paediatrics, University of Melbourne, n/a, Parkville, 3052, Victoria, Australia

    Paul Monagle

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© 2013 Humana Press

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Ignjatovic, V. (2013). Activated Partial Thromboplastin Time. In: Monagle, P. (eds) Haemostasis. Methods in Molecular Biology, vol 992. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-339-8_8

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  • DOI: https://doi.org/10.1007/978-1-62703-339-8_8

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-338-1

  • Online ISBN: 978-1-62703-339-8

  • eBook Packages: Springer Protocols

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