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Target Organ Toxicity

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Abstract

Several target organs such as liver, kidney, lungs, heart, ocular and visual apparatus, skin, reproductive organ, immune system, endocrine systems, etc. play an important role for various functions of the body. Damage to any system may lead to serious consequences. In addition to medicinal risks, liver and kidney damages accompany exposure to synthetic chemicals in the workplace or as environmental pollutants. Still other chemicals that harm the excretory organs are consumed as food contaminants. The vulnerability of the liver, kidney, and other organs to xenobiotic toxicity raises the question as to why such chemicals often display “organ selectivity” when inducing toxicity. This chapter briefly describes the overview, key points, and relevant text that are in the format of problem-solving study questions followed by multiple-choice questions (MCQs) along with their answers.

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Further Reading

  • Fruncillo RJ (2011) 2,000 Toxicology board review questions. Xlibris, Publishers, USA

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  • Gupta PK (ed) (2010) Modern toxicology, vol 3, 2nd reprint. PharmaMed Press, Hyderabad

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  • Gupta PK (2014) Essential concepts in toxicology. BSP Pvt Ltd, Hyderabad

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  • Gupta PK (2016) Fundamental in toxicology: essential concepts and applications in toxicology, 1st edn. Elsevier/BSP, San Diego

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  • Gupta PK (2018) Illustrative toxicology, 1st edn. Elsevier, San Diego

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  • Gupta RC (2018) Veterinary toxicology: basic and clinical principles, 3rd edn. Academic Press/Elsevier, San Diego

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  • Gupta PK (2019) Concepts and applications in veterinary toxicology: an interactive guide. Springer-Nature, Switzerland

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  • Gupta PK (2020) Brainstorming questions in toxicology. Francis and Taylor CRC Press, Boca Raton

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  • Klaassen CD (ed) (2019) Casarett and Doull’s toxicology: the basic science of poisons, 9th edn. McGraw-Hill, New York

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Gupta, P.K. (2020). Target Organ Toxicity. In: Problem Solving Questions in Toxicology:. Springer, Cham. https://doi.org/10.1007/978-3-030-50409-0_7

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