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Part of the book series: AAPS Introductions in the Pharmaceutical Sciences ((AAPSINSTR,volume 13))

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Abstract

Size reduction refers to the process of the formation of small particles with a large surface area. The stress-strain curve of the material determines the energy needed for size reduction with a desirable particle size distribution. The study of equipment used for size reduction and their process parameters helps to reduce the energy supply. In this chapter, we have discussed the theories describing the energy required during milling, and the equipment used for milling including the ball mill, hammer mill, fluid energy mill, cutter mill, and oscillating granulator. Further, we have explained the factors affecting the size reduction process.

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Correspondence to Anil B. Jindal .

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Jindal, A.B. (2023). Size Reduction. In: Jindal, A.B. (eds) Pharmaceutical Process Engineering and Scale-up Principles. AAPS Introductions in the Pharmaceutical Sciences, vol 13. Springer, Cham. https://doi.org/10.1007/978-3-031-31380-6_8

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