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  • Book
  • © 2012

Immunosenescence

Editors:

  • Describes molecular aspects of the aging immune system
  • Discusses new therapeutic approaches
  • Written by internationally reputed scientists
  • Includes supplementary material: sn.pub/extras

Part of the book series: Birkhäuser Advances in Infectious Diseases (BAID)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xviii
  2. Regulation of Adaptive Immunity in the Elderly

    • Nicola J. Booth, Arne N. Akbar, Milica Vukmanovic-Stejic
    Pages 1-23
  3. Does Innate Immunity Get Old?

    • Chiara Romagnani
    Pages 25-36
  4. Characteristics of B Cells and B Cell Responses in Aged Individuals

    • Henrik E. Mei, Andreas Radbruch
    Pages 55-84
  5. CMV Subversion of the Immune System in Later Life

    • Fiona Powell, Florian Kern
    Pages 127-143
  6. Aging and Autoimmunity

    • Ulf Wagner
    Pages 145-155
  7. Vaccination in the Elderly

    • Birgit Weinberger, Beatrix Grubeck-Loebenstein
    Pages 157-174
  8. Immunosenescence and the 3Rs: Restoration, Replacement and Reprogramming

    • Wayne A. Mitchell, Ryan C. Pink, Antonio Lapenna, Richard Aspinall
    Pages 175-200
  9. Back Matter

    Pages 229-235

About this book

As individuals age, their ability to respond to and clear pathogens and to control unwanted immune reactions declines, leading to a greater incidence of certain infectious diseases, autoimmunity and general immune dysfunctions. Most remarkably, the efficacy of vaccines is frequently decreased in elderly persons. Therefore, age-associated dysfunctions of the humoral and cellular immune responses have a strong clinical impact. Improving our understanding of the aged immune system is crucial in developing effective prevention and treatment programs that will facilitate healthy aging and improve the quality of life of the elderly population.

The aim of this volume is to summarize current knowledge on the cellular and molecular aspects of the aging immune system, with an emphasis on infectious diseases and new therapeutic approaches.

Editors and Affiliations

  • Campus Virchow-Klinikum, Berlin-Brandenburg Center for, Charité - Universitätsmedizin Berlin, Berlin, Germany

    Andreas Thiel

Bibliographic Information

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access