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Developments in Medical Image Processing and Computational Vision pp 105–119Cite as

Tracking Red Blood Cells Flowing through a Microchannel with a Hyperbolic Contraction: An Automatic Method

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Part of the book series: Lecture Notes in Computational Vision and Biomechanics ((LNCVB,volume 19))

Abstract

The present chapter aims to assess the motion and deformation index of red blood cells (RBCs) flowing through a microchannel with a hyperbolic contraction using an image analysis based method. For this purpose, a microchannel containing a hyperbolic contraction was fabricated in polydimethylsiloxane by using a soft-lithography technique and the images were captured by a standard high-speed microscopy system. An automatic image processing and analyzing method has been developed in a MATLAB environment, not only to track both healthy and exposed RBCs motion but also to measure the deformation index along the microchannel. The keyhole model has proved to be a promising technique to track automatically healthy and exposed RBCs flowing in this kind of microchannels.

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Acknowledgements

The authors acknowledge the financial support provided by PTDC/SAUBEB/105650/2008, PTDC/SAU-ENB/116929/2010, EXPL/EMS-SIS/2215/2013 from FCT (Science and Technology Foundation), COMPETE, QREN and European Union (FEDER).

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Authors and Affiliations

  1. ESTiG, IPB, C. Sta. Apolonia, 5301-857, Bragança, Portugal

    B. Taboada, F. C. Monteiro & R. Lima

  2. CEFT, FEUP, R. Dr. Roberto Frias, 4200-465, Porto, Portugal

    B. Taboada & R. Lima

  3. University of Minho, Mechanical Engineering Department, Campus de Azurém, 4800-058, Guimarães, Portugal

    R. Lima

Authors
  1. B. Taboada
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  2. F. C. Monteiro
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  3. R. Lima
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Corresponding author

Correspondence to B. Taboada .

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Editors and Affiliations

  1. Department of mechanical engineering, Universidade do Porto, Porto, Portugal

    João Manuel R. S. Tavares

  2. Universidade do Porto, Porto, Portugal

    Renato Natal Jorge

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Taboada, B., Monteiro, F., Lima, R. (2015). Tracking Red Blood Cells Flowing through a Microchannel with a Hyperbolic Contraction: An Automatic Method. In: Tavares, J., Natal Jorge, R. (eds) Developments in Medical Image Processing and Computational Vision. Lecture Notes in Computational Vision and Biomechanics, vol 19. Springer, Cham. https://doi.org/10.1007/978-3-319-13407-9_7

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  • DOI: https://doi.org/10.1007/978-3-319-13407-9_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-13406-2

  • Online ISBN: 978-3-319-13407-9

  • eBook Packages: EngineeringEngineering (R0)

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