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Anxiety in Autism Spectrum Disorder

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Psychiatric Symptoms and Comorbidities in Autism Spectrum Disorder

Abstract

Anxiety appears to be more common in Autism Spectrum Disorder (ASD) than in both the general population and various clinical groups, with possibly up to 40 % of individuals in the autism spectrum presenting elevated levels of at least on anxiety subtype. In this chapter we will critically evaluate the current state of knowledge on the nature of anxiety issues in individuals with ASD, provide an overview of clinical management issues and best practices, and discuss current and future research directions.

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References

  • Achenbach TM, Rescorla LA (2001) Manual for the ASEBA School-Age Forms and Profiles. Burlington, VT: University of Vermont, Research Center for Children, Youth, and Families

    Google Scholar 

  • Asperger H (1944) Die autistischen psychopathen in Kindersalten. Arch Psychiatr Nervenkrankenheiten 117:76–136

    Article  Google Scholar 

  • Aylward EH, Minshew NJ, Goldstein G, Honeycutt NA, Augustine AM, Yates KO, Barta PE, Pearlson GD (1999) MRI volumes of amygdala and hippocampus in non- mentally retarded autistic adolescents and adults. Neurology 53(9):2145–2150

    Article  CAS  PubMed  Google Scholar 

  • Baldwin DS, Waldman S, Allgulander C (2011) Evidence-based pharmacological treatment of generalized anxiety disorder. Int J Neuropsychopharmacol 14(5):697–710

    Article  CAS  PubMed  Google Scholar 

  • Baron-Cohen S (1997) Mindblindness: an essay on autism and theory of mind. MIT Press, Boston

    Google Scholar 

  • Bauman M, Kemper TL (1985) Histoanatomic observations of the brain in early infantile autism. Neurology 35:866–874

    Article  CAS  PubMed  Google Scholar 

  • Beitchman JH, Wilson B, Johnson CJ, Atkinson L, Young A, Adlaf E, Escobar M, Douglas L (2001) Fourteen-year follow-up of speech/language-impaired and control children: psychiatric outcome. J Am Acad Child Adolesc Psychiatry 40(1):75–82

    Article  CAS  PubMed  Google Scholar 

  • Bejerot S, Eriksson JM, Mörtberg E (2014) Social anxiety in adult autism spectrum disorder. Psychiatry Res 220:705–707

    Article  PubMed  Google Scholar 

  • Bellini S (2004) Social skill deficits and anxiety in high-functioning adolescents with autism spectrum disorders. Focus Autism Other Dev Disabil 19(2):78–86

    Article  Google Scholar 

  • Bellini S (2006) The development of social anxiety in adolescents with autism spectrum disorders. Focus on Autism and Other Developmental Disabilities, 21(3):138–145

    Google Scholar 

  • Ben-Sasson A, Cermak SA, Orsmond GI, Tager-Flusberg H, Carter AS, Kadlec MB (2008) Sensory subgroups of toddlers with autism spectrum disorders: differences in internalizing symptoms. J Child Psychol Psychiatry 49(8):817–825

    Article  CAS  PubMed  Google Scholar 

  • Berthoz S, Hill EL (2005) The validity of using self-reports to assess emotion regulation abilities in adults with autism spectrum disorder. Eur Psychiatry 20(3):291–298

    Article  PubMed  Google Scholar 

  • Birmaher B, Brent DA, Chiappetta L, Bridge J, Monga S, Baugher M (1999) Psychometric properties of the Screen for Child Anxiety Related Emotional Disorders (SCARED): a replication study. J Am Acad Child Adolesc Psychiatry 38:1230–1236

    Article  CAS  PubMed  Google Scholar 

  • Birmaher B, Khetarpal S, Brent D, Cully M, Balach L, Kaufman J, Neer MS (1997) The Screen for Child Anxiety Related Emotional Disorders (SCARED): scale construction and psychometric characteristics. J Am Acad Child Adolesc Psychiatry 36:545–553

    Article  CAS  PubMed  Google Scholar 

  • Bornstein MH, Hahn CS, Suwalsky JT (2013) Language and internalizing and externalizing behavioral adjustment: developmental pathways from childhood to adolescence. Dev Psychopathol 25(3):857–878

    Article  PubMed  PubMed Central  Google Scholar 

  • Bradley EA, Summers JA, Wood HL, Bryson SE (2004) Comparing rates of psychiatric and behavior disorders in adolescents and young adults with severe intellectual disability with and without autism. J Autism Dev Disord 34:151–161

    Article  PubMed  Google Scholar 

  • Buitelaar JK, van der Gaag RJ, van der Hoeven J (1998) Buspirone in the management of anxiety and irritability in children with pervasive developmental disorders: results of an open-label study. J Clin Psychiatry 59(2):56–59

    Article  CAS  PubMed  Google Scholar 

  • Burnette CP, Mundy PC, Meyer JA, Sutton SK, Vaughan AE, Charak D (2005) Weak central coherence and its relations to theory of mind and anxiety in autism. J Autism Dev Disord 35:63–73

    Article  PubMed  Google Scholar 

  • Carter EW, Lane KL, Cooney M, Weir K, Moss CK, Machalicek W (2013) Parent assessments of self-determination importance and performance for students with autism or intellectual disability. Am J Intellect Dev Disabil 118(1):16–31

    Article  PubMed  Google Scholar 

  • Chalfant AM, Rapee R, Carroll L (2007) Treating anxiety disorders in children with high functioning autism spectrum disorders: a controlled trial. J Autism Dev Disord 37:1842–1857

    Article  PubMed  Google Scholar 

  • Chorpita BF, Moffitt CE, Gray J (2005) Psychometric properties of the revised child anxiety and depression scale in a clinical sample. Behav Res Ther 43(3):309–322

    Article  PubMed  Google Scholar 

  • Couturier JL, Nicholson R (2002) A retrospective assessment of citalopram in children and adolescents with pervasive developmental disorders. J Child Adolesc Psychopharmacol 12:243–248

    Article  PubMed  Google Scholar 

  • Dadds MR, Rapee RM, Barrett PM (1994) Behavioral observation. In: Ollendick TH, King NJ, Yule W (eds) International handbook of phobic and anxiety disorders in children and adolescents. Plenum, New York, pp 349–364

    Chapter  Google Scholar 

  • Dalton KM, Nacewicz BM, Johnstone T, Schaefer HS, Gernsbacher MA, Goldsmith HH, Alexander AL, Davidson RJ (2005) Gaze fixation and the neural circuitry of face processing in autism. Nat Neurosci 8(4):519–526

    CAS  PubMed  PubMed Central  Google Scholar 

  • Davis III TE, Fodstad JC, Jenkins WS, Hess JA, Moree BN, Dempsey T, … Matson JL (2010) Anxiety and avoidance in infants and toddlers with autism spectrum disorders: evidence for differing symptom severity and presentation. Res Autism Spectr Disord 4:305–313

    Google Scholar 

  • Davis III TE, Hess JA, Moree BN, Fodstad JC, Dempsey T, Jenskins WS,… Matson J (2011a) Anxiety symptoms across the lifespan in people diagnosed with autistic disorder. Res Autism Spectr Disord 5:112–118

    Google Scholar 

  • Davis III TE, Moree BN, Dempsey T, Reuther ET, Fodstad JC, Hess JA, … Matson JL (2011b) The relationship between autism spectrum disorders and anxiety: The moderating effect of communication. Res Autism Spectr Disord 5:324–329

    Google Scholar 

  • Davis TE III (2012) Where to from here for ASD and anxiety? Lessons learned from child anxiety and the issue of DSM-5. Clin Psychol Sci Pract 19:358–363

    Article  Google Scholar 

  • Davis TE III, White SW, Ollendick TH (2014) Handbook of autism and anxiety. Springer, New York

    Book  Google Scholar 

  • de Bruin EI, Ferdinand RF, Meester S, De Nijs PFA, Verheij F (2007) High rates of psychiatric co-morbidity in PDD-NOS. J Autism Dev Disord 37:877–886

    Article  PubMed  Google Scholar 

  • Drahota A, Wood JJ, Sze KM, Van Dyke M (2011) Effects of cognitive behavioral therapy on daily living skills in children with high-functioning autism and concurrent anxiety disorders. J Autism Dev Disord 41(3):257–265

    Article  PubMed  PubMed Central  Google Scholar 

  • Evans DW, Canavera K, Klinepeter FL, Taga K, Maccubbin E (2005) The fears, phobias and anxieties of children with autism spectrum disorders and Down syndrome: comparisons with developmentally and chronologically age matched children. Child Psychiatry Hum Dev 36:3–26

    Article  PubMed  Google Scholar 

  • Farrugia S, Hudson J (2006) Anxiety in adolescents with Asperger syndrome: negative thoughts, behavioral problems, and life interference. Focus Autism Other Dev Disabil 21(1):25–35

    Article  Google Scholar 

  • Gadow KD, Sprafkin J (1997) Early Childhood Inventory-4 norms manual. Stony Brook, NY: Checkmate Plus

    Google Scholar 

  • Gadow KD, DeVincent CJ, Pomeroy J, Azizian A (2005) Comparison of DSM-IV symptoms in elementary school-age children with PDD versus clinic and community samples. Autism 9:392–415

    Article  PubMed  Google Scholar 

  • Gillot A, Furniss F, Walter A (2001) Anxiety in high-functioning children with autism. Autism 5:277–286

    Article  Google Scholar 

  • Gillott A, Standen PJ (2007) Levels of anxiety and sources of stress in adults with autism. J Intellect Disabil 11:359–370

    Article  PubMed  Google Scholar 

  • Gotham K, Bishop SL, Hus V, Huerta M, Lund S, Buja A, Krieger A, Lord C (2013) Exploring the relationship between anxiety and insistence on sameness in autism spectrum disorders. Autism Res 6(1):33–41

    Article  PubMed  PubMed Central  Google Scholar 

  • Grandin, T (1992) An Inside View of Autism. In E. Schopler and G.B. Mesibov (eds), High-Functioning Individuals with Autism. New York: Plenum Press 105–26

    Google Scholar 

  • Green SA, Ben-Sasson A, Soto TW, Carter AS (2012) Anxiety and sensory over-responsivity in toddlers with autism spectrum disorders: bidirectional effects across time. J Autism Dev Disord 42(6):1112–1119

    Article  PubMed  PubMed Central  Google Scholar 

  • Green J, Gilchrist A, Cox A (2000) Social and psychiatric functioning in adolescents with Asperger syndrome compared with conduct disorder. J Autism Dev Disord 30:279–293

    Article  CAS  PubMed  Google Scholar 

  • Greenway R, Howlin P (2010) Dysfunctional attitudes and perfectionism and their relationship to anxious and depressive symptoms in boys with autism spectrum disorders. J Autism Dev Disord 40(10):1179–1187

    Article  Google Scholar 

  • Hagopian LP, Weist MD, Ollendick TH (1990) Cognitive-behavior therapy with an 11-year-old girl fearful of AIDS infection, other diseases, and poisoning: a case study. J Anxiety Disord 4:257–265

    Article  Google Scholar 

  • Hallett V, Ronald A, Colvert E, Ames C, Woodhouse E, Lietz S, Bolton P (2013) Exploring anxiety symptoms in a large-scale twin study of children with autism spectrum disorders, their co-twins and controls. Journal of Child Psychology and Psychiatry, 54(11), 1176–1185

    Google Scholar 

  • Helverschou SB, Martinsen H (2011) Anxiety in people diagnosed with autism and intellectual disability: recognition and phenomenology. Res Autism Spectr Disord 5(1):377–387

    Article  Google Scholar 

  • Helvershou SB, Bakken TL, Martinsen H (2009) The psychopathology in autism (PAC): a pilot study. Res Autism Spectr Disord 3:179–195

    Article  Google Scholar 

  • Hess JA, Matson JL, Dixon DR (2010) Psychiatric symptom endorsements in children and adolescents diagnosed with autism spectrum disorders: a comparison to typically developing children and adolescents. J Dev Phys Disabil 22:485–496

    Article  Google Scholar 

  • Hill EL, Berthoz S, Frith U (2004) Brief report: cognitive processing of own emotions in individuals with autistic spectrum disorder and in their relatives. J Autism Dev Disord 34(2):229–235

    Article  PubMed  Google Scholar 

  • Hollocks MJ, Jones CR, Pickles A, Baird G, Happé F, Charman T, Simonoff E (2014) The association between social cognition and executive functioning and symptoms of anxiety and depression in adolescents with autism spectrum disorders. Autism Res 7(2):216–228

    Article  PubMed  Google Scholar 

  • Howard MA, Cowell PE, Boucher J, Broks P, Mayes A, Farrant A, … Roberts N (2000) Convergent neuroanatomical and behavioral evidence of an amygdala hypothesis of autism. Neuroreport 11:2931–2935

    Google Scholar 

  • Jennett HK, Hagopian LP (2008) Identifying empirically supported treatments for phobic avoidance in individuals with intellectual disabilities. Behav Ther 39:151–161

    Article  PubMed  Google Scholar 

  • Juranek J, Filipek PA, Berenji GR, Modahl C, Osann K, Spence MA (2006) Association between amygdala volume and anxiety level: magnetic resonance imaging (MRI) study in autistic children. J Child Neurol 21(12):1051–1058

    Article  PubMed  Google Scholar 

  • Kaiser MD, Hudac CM, Shultz S, Lee SM, Cheung C, Berken AM, Deen B, Pitskel NB, Sugrue DR, Voos AC, Saulnier CA, Ventola P, Wolf JM, Klin A, Vander Wyk BC, Pelphrey KA (2010) Neural signatures of autism. Proc Natl Acad Sci 107(49):21223–21228

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Kanne S (2013) Diagnostic overshadowing. In: Encyclopedia of autism spectrum disorders. Springer, New York, pp 938–940

    Google Scholar 

  • Kanner L (1943) Autistic disturbances of affective contact. Nerv Child 2:217–250

    Google Scholar 

  • Kashani JH, Orvaschel H (1990) A community study of anxiety in children and adolescents. Am J Psychol 147:313–318

    Article  CAS  Google Scholar 

  • Kendall PC (1994) Treating anxiety disorders in children: results of a randomized clinical trial. J Consult Clin Psychol 62:100–110

    Article  CAS  PubMed  Google Scholar 

  • Kendall PC, Hudson JL, Gosch E, Flannery-Schroeder E, Suveg C (2008) Cognitive-behavioral therapy for anxiety disordered youth: a randomized clinical trial evaluating child and family modalities. J Consult Clin Psychol 76:282–297

    Article  PubMed  Google Scholar 

  • Kerns CM, Kendall PC (2014) Autism and anxiety: overlap, similarities, and differences. In: Handbook of autism and anxiety. Springer Cham Heidelberg New York Dordrecht London, pp 75–89

    Google Scholar 

  • Kerns CM, Kendall PC, Zickgraf H, Franklin ME, Miller J, Herrington J (2015) Not to be overshadowed or overlooked: functional impairments associated with comorbid anxiety disorders in youth with ASD. Behav Ther 46(1):29–39

    Article  PubMed  Google Scholar 

  • Khanna M, Kendall P (2010) Computer-assisted cognitive behavioral therapy for child anxiety: results of a randomized clinical trial. J Consult Clin Psychol 78(5):737–745

    Article  PubMed  Google Scholar 

  • Kim JA, Szatmari P, Bryson SE, Streiner DL, Wilson FJ (2000) The prevalence of anxiety and mood problems among children with Autism and Asperger syndrome. Autism 4:117–132

    Article  Google Scholar 

  • Kleinhans NM, Richards T, Weaver K, Johnson LC, Greenson J, Dawson G, … Alyward E (2010) Association between amygdala response to emotional faces and social anxiety in autism spectrum disorders. Neuropsychologia 48(12):3665–3670

    Google Scholar 

  • Kouijzer MEJ, de Moor JMH, Gerrits BJL, Buitelaar JK, van Schie HT (2009) Long-term effects of neurofeedback treatment in autism. Res Autism Spectr Disord 3(2):496–501

    Article  Google Scholar 

  • Kuusikko S, Pollock-Wurman R, Jussila K, Carter AS, Mattila ML, Ebeling H, Pauls DL, Moilanen I (2008) Social anxiety in high-functioning children and adolescents with autism and Asperger syndrome. J Autism Dev Disord 38(9):1697–1709

    Article  PubMed  Google Scholar 

  • Lecavalier L, Leone S, Wiltz J (2006) The impact of behaviour problems on caregiver stress in young people with autism spectrum disorders. J Intellect Disabil Res 50(3):172–183

    Article  CAS  PubMed  Google Scholar 

  • Leyfer OT, Folstein SE, Bacalman S, Davis NO, Dinh E, Morgan J, Tager-Flusberg H, Lainhart JE (2006) Comorbid psychiatric disorders in children with autism: interview development and rates of disorders. J Autism Dev Disord 36:849–861

    Article  PubMed  Google Scholar 

  • Lidstone J, Uljarević M, Sullivan J, Rodgers J, McConachie H, Freeston M, … Leekam SR (2014) Relations among restricted and repetitive behaviors, anxiety and sensory features in children with autism spectrum disorders. Res Autism Spectr Disord 8(2):82–92

    Google Scholar 

  • Lopata C, Toomey JA, Fox JD, Volker MA, Chow SY, Thomeer ML, Lee GK, Rodgers JD, McDonald CA, Smerbeck AM (2010) Anxiety and depression in children with HFASDs: symptom levels and source differences. J Abnorm Child Psychol 38(6):765–776

    Article  PubMed  Google Scholar 

  • March JS (1997). Manual for multidimensional anxiety scale for children. Tonawanda, NY: Multi-Health System Inc

    Google Scholar 

  • Martin A, Koenig K, Anderson G, Scahill L (2003) Low dose fluvoxamine treatment of children and adolescents with pervasive developmental disorders: A prospective, open-label study. J Autism Dev Disord 33(1):77–85

    Article  PubMed  Google Scholar 

  • Matson JL, Benavidez DA, Compton LS, Paclawskyj T, Baglio C (1996) Characteristics of autism as assessed by the diagnostic assessment for the severely handicappated-II (DASH-II). Res Dev Disab 17, 135–143

    Google Scholar 

  • Matson JL, Boisjoli JA, Wilkins J (2007) The Baby and Infant Screen for Children with aUtIsm Traits (BISCUIT). Disability Consultants, Baton Rouge

    Google Scholar 

  • Matson JL, Gonzalez ML (2007) Autism spectrum disorders – comorbidity – child version. Disability Consultants, Baton Rouge

    Google Scholar 

  • Matson JL, Hess JA, Boisjoli JA (2010) Comorbid psychopathology in infants and toddlers with autism and pervasive developmental disorders – not otherwise specified (PDD-NOS). Res Autism Spectr Disord 4(2):300–304

    Article  Google Scholar 

  • Matson JL, Wilkins J (2008) Reliability of the Autism Spectrum Disorders-Comorbid for Children (ASD-CC). J Dev Phys Disabil 20(4):327–336. doi:10.1007/s10882-008-9100-1

    Article  Google Scholar 

  • Mayes SD, Calhoun SL, Aggarwal R, Baker C, Mathapati S, Molitoris S, Mayes RD (2013) Unusual fears in children with autism. Res Autism Spectr Disord 7(1):151–158

    Article  Google Scholar 

  • Mazefsky CA, Herrington J (2014) Autism and anxiety: etiologic factors and transdiagnostic processes. In: Handbook of autism and anxiety. Springer International Publishing, pp 91–103

    Google Scholar 

  • Mazefsky CA, Kao J, Oswald DP (2011) Preliminary evidence suggesting caution in the use of psychiatric self-report measures with adolescents with high-functioning autism spectrum disorders. Res Autism Spectr Disord 5:164–174

    Article  PubMed  PubMed Central  Google Scholar 

  • Mazefsky CA, Herrington J, Siegel M, Scarpa A, Maddox BB et al (2013) The role of emotion regulation in autism spectrum disorder. J Am Acad Child Adolesc Psychiatry 52:679–688

    Article  PubMed  PubMed Central  Google Scholar 

  • Mazefsky CA, Oswald DP, Day TN, Eack SM, Minshew NJ, Lainhart JE (2012) ASD, a psychiatric disorder, or both? Psychiatric diagnoses in adolescents with high-functioning ASD. J Clin Child Adolesc Psychol 41(4):516–523

    Article  PubMed  PubMed Central  Google Scholar 

  • Mazurek MO, Kanne SM (2010) Friendship and internalizing symptoms among children and adolescents with ASD. J Autism Dev Disabil 40(12):1512–1520

    Article  Google Scholar 

  • Mazurek MO, Vasa RA, Kalb LG, Kanne SM, Rosenberg D, Keefer A, Murray DS, Freedman B, Lowery LA (2013) Anxiety, sensory over-responsivity, and gastrointestinal problems in children with autism spectrum disorders. J Abnorm Child Psychol 41(1):165–176

    Article  PubMed  Google Scholar 

  • McNally Keehn RH, Lincoln AJ, Brown MZ, Chavira DA (2013) The coping cat program for children with anxiety and autism spectrum disorder: a pilot randomized controlled trial. J Autism Dev Disord 43(1):57–67

    Article  PubMed  PubMed Central  Google Scholar 

  • Menon V, Udin LQ (2010) Saliency, switching, attention and control: a network model of insula function. Brain Struct Funct 214(5–6):655–667

    Article  PubMed  PubMed Central  Google Scholar 

  • Mesibov GB, Shea V, Schopler E (2004) The TEACCH approach to autism spectrum disorders. New York: Springer Science & Business Media

    Google Scholar 

  • Meyer JA, Mundy PC, van Hecke AV, Durocher JS (2006) Social attribution processes and comorbid psychiatric symptoms in children with Asperger syndrome. Autism 10(4):383–402

    Article  PubMed  PubMed Central  Google Scholar 

  • Muris P, Steerneman P, Merckelbach H, Holdrinet I, Meesters C (1998) Comorbid anxiety symptoms in children with pervasive developmental disorders. J Anxiety Disord 12:387–393

    Article  CAS  PubMed  Google Scholar 

  • Namerow LB, Prakash T, Bostic JQ, Prince J, Monuteaux MC (2003) Use of citalopram in pervasive developmental disorders. J Dev Behav Pediatr 24:104–108

    Article  PubMed  Google Scholar 

  • Paulus MP, Stein MB (2006) An insular view of anxiety. Biol Psychiatry 60:383–387

    Article  PubMed  Google Scholar 

  • Pellecchia M, Connell JE, Kerns CM, Xie M, Marcus SC, Mandell DS (2015) Child characteristics associated with outcome for children with autism in a school-based behavioral intervention. Autism 1362361315577518

    Google Scholar 

  • Pierce K, Muller RA, Ambrose J, Allen G, Courchesne E (2001) Face processing occurs outside the fusiform ‘face area’ in autism: evidence from functional MRI. Brain 124:2059–2073

    Article  CAS  PubMed  Google Scholar 

  • Prizant B, Wetherby A, Rubin E, Laurent A, Rydell P (2006) The SCERTS® model: a comprehensive educational approach for children with autism spectrum disorders, vol 1 and 2. Paul H. Brookes, Baltimore

    Google Scholar 

  • Reaven J, Blakeley-Smith A, Leuthe E, Moody E, Hepburn S (2012) Facing your fears in adolescence: cognitive-behavioral therapy for high-functioning autism spectrum disorders and anxiety. Autism Res Treat. doi: 10.1155/2012/423905

    Google Scholar 

  • Renno P, Wood JJ (2013) Discriminant and convergent validity of the anxiety construct in children with autism spectrum disorders. J Autism Dev Disord 43(9):2135–2146

    Article  PubMed  PubMed Central  Google Scholar 

  • Reynolds CR, Kamphaus RW (2004) Manual: behavior assessment system for children, 2nd edn. American Guidance Service, Circle Pines

    Google Scholar 

  • Rodgers J, Riby DM, Janes E, Connolly B, McConachie H (2012a) Anxiety and repetitive behaviours in autism spectrum disorders and Williams syndrome: a cross-syndrome comparison. J Autism Dev Disord 42(2):175–180

    Google Scholar 

  • Rodgers J, Glod M, Connolly B, McConachie H (2012b) The relationship between anxiety and repetitive behaviours in autism spectrum disorders. J Autism Dev Disord 42(11):2404–2409

    Google Scholar 

  • Russell E, Sofronoff K (2005) Anxiety and social worries in children with Asperger syndrome. Aust N Z J Psychiatry 39:633–638

    Article  PubMed  Google Scholar 

  • Shaffer D, Fisher P, Lucas CP, Dulcan MK, Schwab-Stone ME (2000) Diagnostic interview schedule for children version IV (DISC-IV): description, differences from previous versions, and reliability of some common diagnoses. J Am Acad Child Adolesc Psychiatry 39(1):28–38

    Google Scholar 

  • Shin LM, Liberzon I (2010) The neurocircuitry of fear, stress, and anxiety disorders. Neuropsychopharmacology 35(1):169–191

    Article  PubMed  PubMed Central  Google Scholar 

  • Silverman W, Albano AM (1996) Manual for the anxiety disorders interview schedule for DSM-IV: child and parent versions. Psychological Corporation, San Antonio

    Google Scholar 

  • Solomon M, Ozonoff S, Carter C, Caplan R (2008) Formal thought disorder and the autism spectrum: relationship between symptoms, executive control, and anxiety. J Autism Dev Disord 38:1474–1484

    Article  PubMed  Google Scholar 

  • Sparks BF, Friedman SD, Shaw DW, Aylward EH, Echelard D, Artru AA, Maravilla KR, Giedd JN, Munson J, Dawson G, Dager SR (2002) Brain structural abnormalities in young children with autism spectrum disorder. Neurology 59:184–192

    Article  CAS  PubMed  Google Scholar 

  • Spence SH (1998) A measure of anxiety symptoms among children. Behav Res Ther 36(5):545–566

    Article  CAS  PubMed  Google Scholar 

  • Sterling L, Renno P, Storch EA, Ehrenreich-May J, Lewin AB, Arnold E, Lin E, Wood J (2015) Validity of the Revised Children’s Anxiety and Depression Scale for youth with autism spectrum disorders. Autism. 2015 Jan;19(1):113–7. doi: 10.1177/1362361313510066

    Google Scholar 

  • Storch EA, May JE, Wood JJ, Jones AM, De Nadai AS, Lewin AB, Arnold EB, Murpy TK (2012) Multiple informant agreement on the anxiety disorders interview schedule in youth with autism spectrum disorders. J Child Adolesc Psychopharmacol 22(4):292–299

    Article  PubMed  PubMed Central  Google Scholar 

  • Strang JF, Kentworthy L, Daniolos P, Case L, Willis MC, Martin A, Wallace GL (2012) Depression and anxiety symptoms in children and adolescents with autism spectrum disorders without intellectual disability. Res Autism Spectr Disord 6:406–412

    Article  PubMed  PubMed Central  Google Scholar 

  • Sukhodolsky DG, Scahill L, Gadow KD, Arnold LE, Aman MG, McDougle CJ, Tierney E, Williams White S, Lecavalier L, Vitiello B (2008) Parent-rated anxiety symptoms in children with pervasive developmental disorders: frequency and association with core autism symptoms and cognitive functioning. J Abnorm Child Psychol 36(1):117–128

    Google Scholar 

  • Sze KM, Wood JJ (2007) Cognitive behavioral treatment of comorbid anxiety disorders and social difficulties in children with high functioning autism: a case report. J Contemp Psychother 37:133–143

    Article  Google Scholar 

  • Sze KM, Wood JJ (2008) Enhancing CBT for the treatment autism spectrum disorders and concurrent anxiety. Behav Cogn Psychother 36:403–409

    Article  Google Scholar 

  • Tager-Flusberg H, Kasari C (2013) Minimally verbal school-aged children with autism spectrum disorder: the neglected end of the spectrum. Autism Res 6(6):468–478

    Article  PubMed  Google Scholar 

  • Tsai LY (1996) Brief report: comorbid psychiatric disorders of autistic disorder. J Autism Dev Disord 26:159–164

    Article  CAS  PubMed  Google Scholar 

  • Turner-Brown LM, Lam KS, Holtzclaw TN, Dichter GS, Bodfish JW (2011) Phenomenology and measurement of circumscribed interests in autism spectrum disorders. Autism 15(4):437–456

    Article  PubMed  PubMed Central  Google Scholar 

  • van Steensel FJ, Bogels SM, Perrin S (2011) Anxiety disorders in children and adolescents with autistic spectrum disorders: a meta-analysis. Clin Child Fam Psychol Rev 14:302–317

    Article  PubMed  PubMed Central  Google Scholar 

  • Vivanti G, McCormick C, Young GS, Abucayan F, Hatt N, Nadig A, Ozonoff S, Rogers SJ (2011) Intact and impaired mechanisms of action understanding in autism. Dev Psychol 47(3):841

    Article  PubMed  Google Scholar 

  • Warren SL, Sroufe LA (2004) Developmental issues. In: Ollendick TH, March JS (eds) Phobic and anxiety disorders in children and adolescents: a clinicians guide to effective psychosocial and pharmacological interventions. Oxford University Press, New York, pp 92–115

    Chapter  Google Scholar 

  • Weisbrot DM, Gadow KD, DeVincent CJ, Pomeroy J (2005) The presentation of anxiety in children with pervasive developmental disorders. J Child Adolesc Psychopharmacol 15:477–496

    Article  PubMed  Google Scholar 

  • Wells R, Outhred T, Heathers JAJ, Quintana DS, Kemp AH (2012) Matter over mind: a randomised-controlled trial of single-session biofeedback training on performance anxiety and heart rate variability in musicians. PLoS One 7(10):e46597

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • White SW, Oswald D, Ollendick T, Scahill L (2009) Anxiety in children and adolescents with autism spectrum disorders. Clin Psychol Rev 29:216–229

    Article  PubMed  PubMed Central  Google Scholar 

  • Wood JJ, Gadow KD (2010) Exploring the nature and function of anxiety in youth with autism spectrum disorders. Clin Psychol Sci Pract 17(4):281–292

    Article  Google Scholar 

  • Wood JJ, Drahota A, Sze K, Har K, Chiu K, Langer DA (2009) Cognitive behavioral therapy for anxiety in children with autism spectrum disorders: a randomized, controlled trial. J Child Psychol Psychiatry 50(3):224–234

    Article  PubMed  PubMed Central  Google Scholar 

  • Worley JA, Matson JL, Sipes M, Koziowski AM (2010) Prevalence of autism spectrum disorders in toddlers receiving early intervention services. Res Autism Spectr Disord 5:920–925

    Article  Google Scholar 

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Authors and Affiliations

  1. La Trobe University, Melbourne, Australia

    Mirko Uljarevic

  2. University of Pennsylvania, Philadelphia, USA

    Heather Nuske

  3. AJ Drexel Autism Institute, Drexel University, Philadelphia, USA

    Giacomo Vivanti

Authors
  1. Mirko Uljarevic
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  2. Heather Nuske
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  3. Giacomo Vivanti
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Corresponding author

Correspondence to Giacomo Vivanti .

Editor information

Editors and Affiliations

  1. Children's Hospital Bambino Gesù, Rome, Italy

    Luigi Mazzone

  2. National Institute of Mental Health, Bethesda, Maryland, USA

    Benedetto Vitiello

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© 2016 Springer International Publishing Switzerland

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Uljarevic, M., Nuske, H., Vivanti, G. (2016). Anxiety in Autism Spectrum Disorder. In: Mazzone, L., Vitiello, B. (eds) Psychiatric Symptoms and Comorbidities in Autism Spectrum Disorder. Springer, Cham. https://doi.org/10.1007/978-3-319-29695-1_2

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  • DOI: https://doi.org/10.1007/978-3-319-29695-1_2

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-29693-7

  • Online ISBN: 978-3-319-29695-1

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