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Schizophrenia Spectrum Disorders and Autism Spectrum Disorder

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Psychiatric Symptoms and Comorbidities in Autism Spectrum Disorder

Abstract

Schizophrenia spectrum disorders (SSD) and autism spectrum disorder (ASD) are currently conceptualised as separate illnesses; however, this has not always been the case. The disorders share multiple phenotypic similarities and risk factors and have been reported to co-occur at elevated rates. In this chapter, we examine the level of comorbidity found between the disorders and the overlap between ASD and SSD at a clinical and trait level and discuss difficulties in the diagnosis and evaluation of the disorders. We then discuss genetic and neurobiological evidence, highlighting similarities and areas of distinction. Finally, we present treatment options, including non-medical and novel treatment strategies as well as pharmacological interventions.

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Authors and Affiliations

  1. School of Psychology, University of Birmingham, Birmingham, UK

    Katharine Chisholm

  2. Telethon Kids Institute, The University of Western Australia, Perth, Australia

    Ashleigh Lin

  3. Child and Adolescence Neuropsychiatry Unit, Department of Neuroscience, I.R.C.C.S. Bambino Gesù Children’s Hospital, Rome, Italy

    Marco Armando

  4. Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva, Switzerland

    Marco Armando

Authors
  1. Katharine Chisholm
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  2. Ashleigh Lin
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  3. Marco Armando
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Corresponding author

Correspondence to Katharine Chisholm .

Editor information

Editors and Affiliations

  1. Children's Hospital Bambino Gesù, Rome, Italy

    Luigi Mazzone

  2. National Institute of Mental Health, Bethesda, Maryland, USA

    Benedetto Vitiello

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© 2016 Springer International Publishing Switzerland

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Chisholm, K., Lin, A., Armando, M. (2016). Schizophrenia Spectrum Disorders and Autism Spectrum Disorder. In: Mazzone, L., Vitiello, B. (eds) Psychiatric Symptoms and Comorbidities in Autism Spectrum Disorder. Springer, Cham. https://doi.org/10.1007/978-3-319-29695-1_4

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  • DOI: https://doi.org/10.1007/978-3-319-29695-1_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-29693-7

  • Online ISBN: 978-3-319-29695-1

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