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Tumoren ohne eindeutige Differenzierungsrichtung

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Pathologie

Zusammenfassung

Die mesenchymalen Tumoren ohne eindeutige Differenzierungsrichtung umfassen eine sehr heterogene Gruppe von Neoplasien, für die überwiegend kein klares Konzept hinsichtlich einer Liniendifferenzierung bzw. eines entsprechenden nicht-neoplastischen Zelltyps besteht. Bei einigen der hier eingeschlossenen Tumoren ist andererseits eine Liniendifferenzierung deutlich (z.B. Klarzellsarkom, Synovialsarkom), ohne daß in diesen Fällen jedoch der entsprechende nicht-neoplastische Zelltyp im Weichgewebe zu identifizieren ist. In die Gruppe der mesenchymalen Tumoren ohne eindeutige Differenzierungsrichtung wurden insbesondere auch eine Anzahl von Neoplasien mit intermediärem biologischen Potential aufgenommen, wie z.B. das angiomatoide fibröse Histiozytom, das Myoepitheliom (Mischtumor) des Weichgewebes und der pleomorphe hyalinisierende angieektatische Tumor des Weichgewebes. Es bleibt abzuwarten, inwieweit sich zukünftig für die große Gruppe der mesenchymalen Tumoren ohne eindeutige Differenzierungsrichtung weitergehende überzeugende Erkenntnisse für eine distinkte Linienzugehörigkeit bzw. Differenzierungsrichtung ergeben.

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Authors and Affiliations

  1. Institut für Pathologie, Clemenshospital Münster, Düesbergweg 128, 48153, Münster, Deutschland

    Cornelius Kuhnen

  2. Institut für Pathologie, Universität Magdeburg, Leipziger Straße 44, 39120, Magdeburg, Deutschland

    Regine Schneider-Stock

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  1. Cornelius Kuhnen
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Editors and Affiliations

  1. Department of Pathological Anatomy, Hospital Clinic, University of Barcelona, Villarroel 170, 08036, Barcelona, Spanien

    Antonio Cardesa

  2. Pathologisches Institut, Mühlenstr. 31, 45759, Recklinghausen, Deutschland

    Pierre Rudolph

  3. Dermatopathologische Gemeinschaftspraxis, Siemensstr. 6/1, 88048, Friedrichshafen, Deutschland

    Thomas Mentzel

  4. Department of Pathology HP 437, University Medical Center St. Radbound, P.O. Box 9101, 6500, Nijmegen, Niederlande

    Pieter J. Slootweg

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Kuhnen, C., Schneider-Stock, R. (2009). Tumoren ohne eindeutige Differenzierungsrichtung. In: Cardesa, A., Rudolph, P., Mentzel, T., Slootweg, P. (eds) Pathologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-72885-6_21

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  • DOI: https://doi.org/10.1007/978-3-540-72885-6_21

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