Abstract
In this paper, we present a method to simulate and visualize blood flow through the human heart, using the reconstructed 4D motion of the endocardial surface of the left ventricle as boundary conditions. The reconstruction captures the motion of the full 3D surfaces of the complex features, such as the papillary muscles and the ventricular trabeculae. We use visualizations of the flow field to view the interactions between the blood and the trabeculae in far more detail than has been achieved previously, which promises to give a better understanding of cardiac flow. Finally, we use our simulation results to compare the blood flow within one healthy heart and two diseased hearts.
Chapter PDF
Similar content being viewed by others
Keywords
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
References
de Zelicourt, D., Ge, L., Wang, C., Sotiropoulos, F., Gilmanov, A., Yoganathan, A.: Flow simulations in arbitrarily complex cardiovascular anatomies - an unstructured cartesian grid approach. Computers & Fluids 38(9), 1749–1762 (2009)
Foster, N., Metaxas, D.: Realistic animation of liquids. Graph. Models Image Process. 58, 471–483 (1996)
Gao, M., Huang, J., Zhang, S., Qian, Z., Voros, S., Metaxas, D., Axel, L.: 4D cardiac reconstruction using high resolution ct images. In: Metaxas, D., Axel, L. (eds.) FIMH (2011)
Gilmanov, A., Sotiropoulos, F.: A hybrid cartesian/immersed boundary method for simulating flows with 3D, geometrically complex, moving bodies. J. Comput. Phys. 207(2), 457–492 (2005)
Jones, T.N., Metaxas, D.: Patient-specific analysis of left ventricular blood flow. In: Wells, W.M., Colchester, A.C.F., Delp, S.L. (eds.) MICCAI 1998. LNCS, vol. 1496, pp. 156–166. Springer, Heidelberg (1998)
Krittian, S., Janoske, U., Oertel, H., Bhlke, T.: Partitioned fluid-solid coupling for cardiovascular blood flow. Annals of Biomedical Engineering 38, 1426–1441 (2010)
Kulp, S., Metaxas, D., Qian, Z., Voros, S., Axel, L., Mihalef, V.: Patient-specific modeling and visualization of blood flow through the heart. In: Wright, S., Pan, X., Liebling, M. (eds.) ISBI (2011)
Long, Q., Merrifield, R., Yang, G.Z., Xu, X.Y., Kilner, P.J., Firmin, D.N.: The influence of inflow boundary conditions on intra left ventricle flow predictions. Journal of Biomechanical Engineering 125(6), 922–927 (2003)
Mihalef, V., Ionasec, R., Wang, Y., Zheng, Y., Georgescu, B., Comaniciu, D.: Patient-specific modeling of left heart anatomy, dynamics and hemodynamics from high resolution 4d CT. In: Niessen, W., Meijering, E. (eds.) ISBI, pp. 504–507 (2010)
Mihalef, V., Metaxas, D., Sussman, M.: Textured liquids based on the marker level set. Comput. Graph. Forum 26(3), 457–466 (2007)
Plank, G., Burton, R., Hales, P., Bishop, M., Mansoori, T., Burton, M., Garny, A., Prassl, A., Bollensdorff, C., Mason, F., Mahmood, F., Rodriguez, B., Grau, V., Schneider, J., Gavaghan, D., Kohl, P.: Generation of histo-anatomically representative models of the individual heart: tools and application. In: Phil. Trans. Roy. Soc. (2009)
Sussman, M.: A parallelized, adaptive algorithm for multiphase flows in general geometries. Comput. Struct. 83(6-7), 435–444 (2005)
Yokoi, K., Xiao, F., Liu, H., Fukasaku, K.: Three-dimensional numerical simulation of flows with complex geometries in a regular cartesian grid and its application to blood flow in cerebral artery with multiple aneurysms. Journal of Computational Physics 202(1), 1–19 (2005)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Kulp, S. et al. (2011). Using High Resolution Cardiac CT Data to Model and Visualize Patient-Specific Interactions between Trabeculae and Blood Flow. In: Fichtinger, G., Martel, A., Peters, T. (eds) Medical Image Computing and Computer-Assisted Intervention – MICCAI 2011. MICCAI 2011. Lecture Notes in Computer Science, vol 6891. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-23623-5_59
Download citation
DOI: https://doi.org/10.1007/978-3-642-23623-5_59
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-23622-8
Online ISBN: 978-3-642-23623-5
eBook Packages: Computer ScienceComputer Science (R0)