Skip to main content

Menopausal Symptoms After Breast Cancer Therapy

  • Living reference work entry
  • First Online:
Encyclopedia of Cancer

Definition

Menopause is the permanent cessation of menstruation resulting from loss of ovarian activity. Natural menopause is diagnosed following 12 months of amenorrhea, which is not due to a pathological cause. Menopause secondary amenorrhea (early menopause, surgical menopause) can also be induced by surgery, chemotherapy, and radiotherapy.

Characteristics

Introduction

Breast cancer is one of the most common causes of morbidity and mortality in women of middle years in the western world. There has been a reduction in annual breast cancer death rates in almost all western countries, which may be due to the increasing use of breast screening and adjuvant systemic therapy (admixture populations). As a result, more women are becoming long-term breast cancer survivors.

A common side effect of breast cancer treatment is the earlier onset of menopause or menopausal symptoms. Many women who are premenopausal at diagnosis will develop premature menopause resulting from chemotherapy,...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

References

  • Brufsky A et al (2007) Zoledronic acid inhibits adjuvant letrozole-induced bone loss in postmenopausal women with early breast cancer. J Clin Oncol 25(7):829–836

    Article  CAS  PubMed  Google Scholar 

  • Couzi RJ, Helzlsouer KJ, Fetting JH (1995) Prevalence of menopausal symptoms among women with a history of cancer breast and attitude towards estrogen replacement therapy. J Clin Oncol 13(11):2737–2744

    CAS  PubMed  Google Scholar 

  • Friedrich M et al (1998) The influence of tamoxifen on the maturation index of vaginal epithelium. Clin Exp Obstet Gynecol 25(4):121–124

    CAS  PubMed  Google Scholar 

  • Hickey M, Saunders CM, Stuckey BG (2005) Management of menopausal symptoms in breast cancer patients: an evidence based approach. Lancet Oncol 16(9):687–695

    Article  Google Scholar 

  • Nelson HD, Vesco KK, Haney E et al (2006) Non-hormonal therapies for menopausal hot flashes. Systemic review and meta-analysis. JAMA 295(17):2057–2070

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Vineeta Singh .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer-Verlag Berlin Heidelberg

About this entry

Cite this entry

Singh, V., Saunders, C., Hickey, M. (2015). Menopausal Symptoms After Breast Cancer Therapy. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_3635-2

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-27841-9_3635-2

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-27841-9

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

Publish with us

Policies and ethics