Abstract
An adaptive control model was able to track lung dynamics from sheep that have asthma-like responses. This model can identify airway response during allergen induced bronchoconstriction by adjusting the controller gains for lung resistances. This study examines the rate of adaptation of the controller gains as the airway responses are disturbed by mechanical ventilation. End-tidal CO2 and O2 gasses were also monitored during these disturbances. Mechanical disturbances of the airways can have an immediate and short term relaxing effect on the bronchochonstriction with no apparent changes in end tidal gasses.
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© 2013 Springer-Verlag Berlin Heidelberg
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Koumoundouros, E., Snibson, K.J., Barcham, G., Mareels, I.M.Y. (2013). Tracking Adaptive Controller Gains to examine the effects of mechanical disturbances to the airway tone in sheep that have asthma-like responses. In: Long, M. (eds) World Congress on Medical Physics and Biomedical Engineering May 26-31, 2012, Beijing, China. IFMBE Proceedings, vol 39. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-29305-4_111
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DOI: https://doi.org/10.1007/978-3-642-29305-4_111
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-29304-7
Online ISBN: 978-3-642-29305-4
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