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Atraumatic Transient Focal Cerebral Ischemia in Monkeys

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Cerebral Circulation and Metabolism

Abstract

Anatomical and physiological data have shown that abundant collateral blood supply exists distal to the circle of Willis. This collateral supply may compensate, at least in part, for the decrease in blood flow sustained after middle cerebral artery (MCA) occlusion (3, 11). In addition, cerebral tissue may be much more resistant to diffuse ischemia than has previously been recognized (6). These lines of investigation suggest that early restoration of flow after MCA occlusion might lead to improvement in appropriate stroke patients. This theoretical possibility has become more attractive since the development of feasible microsurgical techniques for MCA embolectomy and superficial temporal artery to MCA bypass grafting (12).

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© 1975 Springer-Verlag New York Inc.

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Crowell, R.M., Olsson, Y. (1975). Atraumatic Transient Focal Cerebral Ischemia in Monkeys. In: Langfitt, T.W., McHenry, L.C., Reivich, M., Wollman, H. (eds) Cerebral Circulation and Metabolism. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65814-3_21

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  • DOI: https://doi.org/10.1007/978-3-642-65814-3_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-65816-7

  • Online ISBN: 978-3-642-65814-3

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