Abstract
Benzophenanthridine alkaloids occur widely in members of the Papaveraceae (poppy family) and have been detected in cell cultures of several species (Furuya et al. 1972, Ikuta et al. 1979, Berlin et al. 1983, Krane et al. 1984). Aspects of production in elicited cultures of Eschscholtzia californica (Schumacher et al. 1987) and Papaver bracteatum (Cline and Coscia 1988) have recently been described. In this regard, our laboratory has demonstrated that a cell line (PBI# 2009) of Papaver somniferum L. initiated approximately 10 years ago (Tarn et al. 1980) synthesizes and accumulates sanguinarine, a quaternary benzophenanthridine alkaloid, when treated with any of a number of elicitor preparations (Eilert et al. 1985). A portion of the sanguinarine is released into the culture medium. This cell line normally accumulates trace quantities, at best, of benzophenanthridines in unelicited suspension culture.
Publication No. NRCC 29147 from the National Research Council of Canada
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Tyler, R.T., Eilert, U., Rijnders, C.O.M., Roewer, I.A., McNabb, C.K., Kurz, W.G.W. (1989). Studies on Benzophenanthridine Alkaloid Production in Elicited Cell Cultures of Papaver somniferum L.. In: Kurz, W.G.W. (eds) Primary and Secondary Metabolism of Plant Cell Cultures II. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74551-5_22
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DOI: https://doi.org/10.1007/978-3-642-74551-5_22
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