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Some Ultrastructural Aspects of Regeneration in 1.32 μm Nd:YAG Laser-Assisted Peripheral Nerve Transplantation

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Peripheral Nerve Lesions
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Abstract

Various types of lasers have already been tested as a substitute for sutures in microsurgical peripheral nerve anastomoses (Almquist et al. 1984; Fischer et al. 1985; Ulrich et al. 1986). In a histological evaluation of experiments using this technique, the 1.32 μm Nd:YAG laser has been found to be suitable but not appreciably superior to epineurial suture alone (Schober et al. 1988). It was advocated to use the 1.32 μm Nd:YAG laser with its inherent property of precise coagulation in peripheral nerve transplantation, a procedure where so far laser application has been restricted to the milliwatt CO2 laser (Richmond 1986). In this report we give an account of some ultrastructural features pertinent to the outcome of regeneration in such an experimental design. A final evaluation must await the conclusion of a larger experimental series, technical details of which are described in another contribution to this volume (Ulrich et al.).

This research was supported by the Ministerium für Wissenschaft und Forschung des Landes Nordrhein-Westfalen, FRG.

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References

  1. Ahmed AM, Weiler RO (1979) The blood-nerve barrier and reconstitution of the perineurium following nerve grafting. Neuropathol Appl Neurobiol 5:469–483.

    Article  PubMed  CAS  Google Scholar 

  2. Almquist EE, Nachemson A, Auth D, Almquist B, Hall S (1984) Evaluation of the use of the argon laser in repairing rat and primate nerves. J Hand Surg (Am) 9:792–799.

    CAS  Google Scholar 

  3. Beggs JL, Fischer DW, Shetter AG (1986) Comparative study of rat sciatic nerve microepineurial anastomoses made with carbon dioxide laser and suture techniques. II. A morphometric analysis of myelinated nerve fibers. Neurosurgery 18:266–269.

    Article  PubMed  CAS  Google Scholar 

  4. Edinger L (1918) Untersuchungen über die Neubildung des durchtrennten Nerven. Dtsch Zeitschr Nervenheilk 58:1–32.

    Article  Google Scholar 

  5. Fischer DW, Beggs JL, Kenshalo DL Jr, Shetter AG (1985) Comparative study of microepineurial anastomoses with the use of CO2 laser and suture techniques in rat sciatic nerves. I. Surgical technique, nerve action potentials, and morphologic studies. Neurosurgery 17:300–308.

    Article  PubMed  CAS  Google Scholar 

  6. Hudson AR, Hunter D, Kline DG, Bratton BR (1979) Histological studies of experimental interfascicular graft repairs. J Neurosurg 51:333–340.

    Article  PubMed  CAS  Google Scholar 

  7. Jenq CB, Coggeshall RE (1986) The effects of an autologous transplant on patterns of regeneration in rat sciatic nerve. Brain Research 364:45–56.

    Article  PubMed  CAS  Google Scholar 

  8. Morris JH, Hudson AR, Weddell G (1972) A study of degeneration and regeneration in the divided rat sciatic nerve based on electron microscopy. IV. Changes in fascicular microtopography, perineurium and endoneural fibroblasts. Z Zeilforsch 124:165–203.

    Article  CAS  Google Scholar 

  9. Noakes PG, Bennett MR (1987) Growth of axons into developing muscles of chick forelimb is preceded by cells that stain with Schwann cell antibodies. J Comp Neurol 259:330–347.

    Article  PubMed  CAS  Google Scholar 

  10. Richmond IL (1986) The use of lasers in nerve repair. In: Fasano AV (ed) Advanced intraoperative technologies in neurosurgery. Springer, Wien New York, pp 175–183.

    Google Scholar 

  11. Schober R, Ulrich F, Sander T, Dürselen H, Hessel S (1986) Laser-induced alteration of collagen substructure allows microsurgical tissue welding. Science 232:1421–1422.

    Article  PubMed  CAS  Google Scholar 

  12. Schober R, Ulrich F, Sander Th (1988) A histological evaluation of experimental nerve anastomoses with the 1.32μm Nd:YAG-laser. Adv Neurosurg 16:31–35.

    Google Scholar 

  13. Thomas PK, Jones DG (1967) The cellular response to nerve injury. II. Regeneration of the perineurium after nerve section. J Anat 101:45–55.

    PubMed  CAS  Google Scholar 

  14. Ulrich F, Sander T, Bock WJ (1986) Anastomosis of the sciatic nerve of the rat with the modified Nd:YAG laser. A preliminary report. In: Waidelich W, Kiefhaber P (eds) Laser/Optoelektronik in der Medizin. Springer, Berlin Heidelberg New York Tokyo, pp 414–417.

    Google Scholar 

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© 1990 Springer-Verlag Berlin Heidelberg

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Schober, R., Ulrich, F., Sander, T. (1990). Some Ultrastructural Aspects of Regeneration in 1.32 μm Nd:YAG Laser-Assisted Peripheral Nerve Transplantation. In: Samii, M. (eds) Peripheral Nerve Lesions. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75611-5_26

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  • DOI: https://doi.org/10.1007/978-3-642-75611-5_26

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-75613-9

  • Online ISBN: 978-3-642-75611-5

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