Abstract
Fetal guinea pigs are frequently used for perinatal investigations, but little is known about the function of their sympathetic nervous system during hypoxemia and asphyxia. To examine the responses of the sympathetic nervous system to oxygen deficiency, we studied plasma and tissue concentration of catecholamines during normoxemia, hypoxemia, and asphyxia in 22 fetal guinea pigs near term (Jelinek and Jensen 1991). Fetal blood was obtained by cardiopuncture in utero under ketamine/xylazine anesthesia of the dam. Catecholamines were determined in plasma and tissue of 15 organs and 14 brain parts by high-performance liquid chromatography with electrochemical detection.
This investigation was supported by the Deutsche Forschungsgemeinschaft (Je 108/4-1)
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
Reference
Jelinek J, Jensen A (1991) Catecholamine concentrations in plasma and organs of fetal guinea pigs during normoxaemia, hypoxaemia and asphyxia. J Dev Physiol 15:145–152
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1992 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Jelinek, J., Jensen, A. (1992). Plasma and Tissue Concentrations of Catecholamines During Normoxemia, Hypoxemia, and Asphyxia in Fetal Guinea Pigs Near Term. In: Künzel, W., Kirschbaum, M. (eds) OXYGEN: Basis of the Regulation of Vital Functions in the Fetus. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77469-0_19
Download citation
DOI: https://doi.org/10.1007/978-3-642-77469-0_19
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-77471-3
Online ISBN: 978-3-642-77469-0
eBook Packages: Springer Book Archive