Overview
Presents current state of the art
Comprehensive work, describing physiological and pathophysiological mechanisms of vascularisation and angiogenesis
Special emphasis is put on reactive oxygen species and role of microRNAs
Includes supplementary material: sn.pub/extras
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Table of contents (18 chapters)
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Molecular Mechanisms
Keywords
About this book
The book presents the overview of the current knowledge in some fields of vascular biology, addressing cellular and molecular aspects of blood-vessel formation and their role in health and disease. The major factors involved in the formation of blood vessels are presented by scientists actively involved in this area of research. Special emphasis is put on the presentation of various molecular mechanisms not addressed in similar works to date. The book is divided into three parts. The first part describes the cells and mediators in angiogenesis. The significance of various populations of potential endothelial progenitors is particularly highlighted. The chapters of the second part focus on molecular mechanisms, with special emphasis on the role of hypoxia, gasotransmitters and reactive oxygen species as well as microRNAs in regulation of angiogenic processes. In the third part, the pathological aspects of disturbed – aggravated or impaired – vascularization are discussed and new modalities for potential therapies are presented. The book is intended for scientists and PhD students in the fields of vascular biology and cancer research. It may be of interest for medical professionals in the fields of cardiovascular disease, diabetes, oncology and rheumatoid arthritis.
Editors and Affiliations
About the editors
Bibliographic Information
Book Title: Angiogenesis and Vascularisation
Book Subtitle: Cellular and Molecular Mechanisms in Health and Diseases
Editors: Józef Dulak, Alicja Józkowicz, Agnieszka Łoboda
DOI: https://doi.org/10.1007/978-3-7091-1428-5
Publisher: Springer Vienna
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Wien 2013
Hardcover ISBN: 978-3-7091-1427-8Published: 19 February 2014
Softcover ISBN: 978-3-7091-1968-6Published: 23 August 2016
eBook ISBN: 978-3-7091-1428-5Published: 10 February 2014
Edition Number: 1
Number of Pages: X, 416
Number of Illustrations: 15 b/w illustrations, 45 illustrations in colour
Topics: Immunology, Cancer Research, Cell Biology, Oncology