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Biomolecule/Nanomaterial Hybrid Systems for Nanobiotechnology

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Nano-Biotechnology for Biomedical and Diagnostic Research

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 733))

Abstract

The integration of biomolecules with metallic or semiconductor nanoparticles or carbon nanotubes yields new hybrid nanostructures of unique features that combine the properties of the biomolecules and of the nano-elements. These unique features of the hybrid biomolecule/nanoparticle systems provide the basis for the rapid development of the area of nanobiotechnology. Recent advances in the implementation of hybrid materials consisting of biomolecules and metallic nanoparticles or semiconductor quantum dots will be discussed. The following topics will be exemplified: (i) The electrical wiring of redox enzymes with electrodes by means of metallic nanoparticles or carbon nanotubes, and the application of the modified electrodes as amperometric biosensors or for the construction of biofuel cells. (ii) The biocatalytic growth of metallic nanoparticles as a means to construct optical or electrical sensors. (iii) The functionalization of semiconductor quantum dots with biomolecules and the application of the hybrid nanostructures for developing different optical sensors, including intracellular sensor systems. (iv) The use of biomolecule-metallic nanoparticle nanostructures as templates for growing metallic nanowires, and the construction of fuel-driven nano-transporters.

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Acknowledgements

The support of the Israel Science Foundation is acknowledged.

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Authors and Affiliations

  1. The Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel

    Ran Tel-Vered, Omer Yehezkeli & Itamar Willner

Authors
  1. Ran Tel-Vered
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  2. Omer Yehezkeli
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  3. Itamar Willner
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Corresponding author

Correspondence to Itamar Willner .

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Editors and Affiliations

  1. Israel Institute for Biological Research, P.O. Box 19, Ness-Ziona, 74100, Israel

    Eran Zahavy

  2. Israel Institute for Biological Research, P.O. Box 19, Ness-Ziona, 74100, Israel

    Arie Ordentlich

  3. Israel Institute for Biological Research, P.O. Box 19, Ness-Ziona, Israel

    Shmuel Yitzhaki

  4. Israel Institute for Biological Research, P.O. Box 19, Ness-Ziona, 74100, Israel

    Avigdor Shafferman

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Tel-Vered, R., Yehezkeli, O., Willner, I. (2012). Biomolecule/Nanomaterial Hybrid Systems for Nanobiotechnology. In: Zahavy, E., Ordentlich, A., Yitzhaki, S., Shafferman, A. (eds) Nano-Biotechnology for Biomedical and Diagnostic Research. Advances in Experimental Medicine and Biology, vol 733. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-2555-3_1

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