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FTIR Imaging of Tissues: Techniques and Methods of Analysis

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Optical Spectroscopy and Computational Methods in Biology and Medicine

Part of the book series: Challenges and Advances in Computational Chemistry and Physics ((COCH,volume 14))

Abstract

In this chapter, we describe biomedical applications of infrared microscopic imaging applied to human tissue sections. The central focus is human diseases including cervical cancer, neurodegenerative pathologies, and dysfunctions of cardiac and liver tissues. In addition, we briefly describe the fundamentals of FTIR imaging instrumentation along with spectral pre-processing and hyperspectral image reconstruction. The chapter concludes with a summary of what is required to take FTIR imaging technology into the clinical environment.

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Acknowledgements

Dr. B.R. Wood is financially supported by an Australian Research Council Future Fellowship FT120100926.

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Authors and Affiliations

  1. Faculty of Chemistry and Jagiellonian Centre for Experimental Therapeutics, Jagiellonian University, Ingardena 3, 30-060, Krakow, Poland

    Kamilla Malek

  2. Centre for Biospectroscopy and School of Chemistry, Monash University, 3800, Victoria, Australia

    Bayden R. Wood

  3. Australian Synchrotron, 800 Blackburn Road, 3168, Clayton, VIC, Australia

    Keith R. Bambery

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  1. Kamilla Malek
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  2. Bayden R. Wood
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  3. Keith R. Bambery
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Correspondence to Kamilla Malek .

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  1. Faculty of Chemistry, Jagiellonian University, Ingardena 3, Krakow, Poland

    Malgorzata Baranska

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Malek, K., Wood, B., Bambery, K. (2014). FTIR Imaging of Tissues: Techniques and Methods of Analysis. In: Baranska, M. (eds) Optical Spectroscopy and Computational Methods in Biology and Medicine. Challenges and Advances in Computational Chemistry and Physics, vol 14. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7832-0_15

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