Abstract
Rate-dependent intraventricular conduction disturbances are of two basic types: 1) those which become manifest when the heart rate is accelerated, and 2) those appearing as a consequence of deceleration. To explain these phenomena, Rosenbaum and coworkers introduced the concept of phase-3 and phase-4 block [1]. Conduction failure of closely coupled beats was termed phase-3 block and was attributed to normal refractoriness or its extension in disease states. Conduction failure of an impulse arriving late in diastole (phase-4 block) was attributed to slow diastolic depolarization (SDD) at the depressed site. In both cases, conduction impairment was attributed to a more positive take-off potential giving rise to responses of lesser amplitude and (dV/dt)max and therefore a diminished conductivity [2–6].
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References
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© 1983 Martinus Nijhoff Publishers, The Hague
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Antzelevitch, C., Jalife, J., Moe, G.K. (1983). Frequency-Dependent Alterations of Conduction in Purkinje Fibers. In: Rosenbaum, M.B., Elizari, M.V. (eds) Frontiers of Cardiac Electrophysiology. Developments in Cardiovascular Medicine, vol 19. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6781-6_20
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DOI: https://doi.org/10.1007/978-94-009-6781-6_20
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