Skip to main content

A Possible Step in the Origin of the Genetic Code

  • Conference paper
Cosmochemical Evolution and the Origins of Life
  • 83 Accesses

Abstract

It is suggested that the earliest coding polynucleotides contained a high proportion of alternating sequences of purines and pyrimidines, and that these sequences coded for polypeptides in which hydrophobic and hydrophylic amino acids alternated. Structural properties of such alternating polypeptides are discussed.

The material covered in this paper was presented previously in the Israel Journal of Chemistry, 10 (1972), pp. 287–292. Dedicated to the Memory of Gerhard M. J. Schmidt.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Crick, F. H. C.: 1968, J. Mol Biol 38, 367.

    Article  Google Scholar 

  • Dickerson, R. E.: 1971, J. Mol Biol 57, 1.

    Article  Google Scholar 

  • Kenyon, D. H. and Steinman, G.: 1969, Biochemical Predestination, McGraw Hill, New York.

    Google Scholar 

  • A. McGlochlen, Private Communication.

    Google Scholar 

  • Orgel, L. E.: 1968, J. Mol Biol 38, 381.

    Article  Google Scholar 

  • Ruska, M. and Mandel, M.: 1971, Proc. Nat. Acad. Sci. U.S. 68, 1190 and references therein.

    Article  Google Scholar 

  • Sulston, J. and Orgel, L. E.: 1970, Second Conference of the Institute de la Vie, Paris; Proceedings of Conference on Origins of Life, Houston, Texas.

    Google Scholar 

  • Woese, C.: 1967, The Genetic Code, Harper and Row, New York.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1974 D. Reidel Publishing Company, Dordrecht, Holland

About this paper

Cite this paper

Orgel, L.E. (1974). A Possible Step in the Origin of the Genetic Code. In: Oró, J., Miller, S.L., Ponnamperuma, C., Young, R.S. (eds) Cosmochemical Evolution and the Origins of Life. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-2282-8_37

Download citation

  • DOI: https://doi.org/10.1007/978-94-010-2282-8_37

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-2284-2

  • Online ISBN: 978-94-010-2282-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics