Abstract
On the basis of a modern integrated approach to receptor characterization, the classification of 5-HT receptors has been reappraised by the Serotonin Club Receptor Nomenclature Committee. This has led to a modified nomenclature which is outlined. The new classification extends the classification of Bradley and colleagues, published in 1986, to include the 5-HT, receptor and several subtypes of the 5-HT, and 5-HT2receptor group. However, it is recognized that the scheme is still incomplete as several 5-HT receptors, including the newly cloned 5HTSreceptor, cannot yet be classified due to lack of adequate characterization data.
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Humphrey, P.P.A., Hartig, P., Hoyer, D. (1993). A Reappraisal of 5-HT Receptor Classification. In: Vanhoutte, P.M., Saxena, P.R., Paoletti, R., Brunello, N., Jackson, A.S. (eds) Serotonin. Medical Science Symposia Series, vol 5. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-1920-7_5
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DOI: https://doi.org/10.1007/978-94-011-1920-7_5
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