Skip to main content

Significance of Fortification of Beneficial Natural Ingredients in Milk and Milk Products

  • Chapter
  • First Online:
Dairy Processing: Advanced Research to Applications

Abstract

Fortification is a process where essential ingredients like vitamins, minerals, omega-3 fatty acids, probiotics, prebiotics and phytoconstituents are incorporated to the dairy products. The main purpose of fortification is to reduce the rate of nutrition deficiency and related diseases among all age group of people. The various dairy products like whole milk, yoghurt, cheese, yoghurt drinks, dairy-based beverages, milk powder, butter, and buttermilk favor the fortification ingredients and a great choice for the essential nutrient fortification. The need for milk fortification with essential nutrients is required because milk and milk products are deficient in some nutrients or the amount is too low (iron) for the proper nutrition intake. Several processing factors such as heating, pasteurization, homogenization, ultrahigh temperature treatment and spray drying can also contribute to the loss of some essential nutrients. Therefore, fortification of milk and milk products was introduced to overcome the lost nutrients and to maintain its stability at the end of the shelf life of the product. Thus, fortification could be considered as a supportive technique to deliver the required micronutrients and other functional ingredients and can serve as a tool to minimize nutrition deficiency and related diseases.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Change history

  • 18 August 2020

    The affiliations in the contributors list in the FM for the editors and in the chapters 1, 8, 10, 11 and 14 were swapped incorrectly.

References

  • Abbasi S, Azari S (2011) Efficiency of novel iron microencapsulation techniques: fortification of milk. Int J Food Sci Technol 46:1927–1933

    CAS  Google Scholar 

  • Abdel-Hameed ES, Nagaty MA, Salman MS, Bazaid SA (2014) Phytochemicals, nutritionals and antioxidant properties of two prickly pear cactus cultivars (Opuntia ficus indica mill.) growing in Taif, KSA. Food Chem 160:31–38

    CAS  Google Scholar 

  • Abedi D, Feizizadeh S, Akbari V, Jafarian-Dehkordi A (2013) In vitro anti-bacterial and anti-adherence effects of Lactobacillus delbrueckii subsp. bulgaricus on Escherichia coli. Res Pharm Sci 8:260–268

    CAS  PubMed  PubMed Central  Google Scholar 

  • Achanta K, Aryana KJ, Boeneke CA (2007) Fat free plain set yogurts fortified with various minerals. LTW Food Sci Technol 40:424–429

    CAS  Google Scholar 

  • Akalin AS, Fenderya S, Akbulut N (2004) Viability and activity of bifidobacteria in yoghurt containing fructooligosaccharide during refrigerated storage. Int J Food Sci Technol 39:613–621

    CAS  Google Scholar 

  • Akalin AS, Unal G, Dinkci N, Hayaloglu AA (2012) Microstructural, textural, and sensory characteristics of probiotic yogurts fortified with sodium calcium caseinate or whey protein concentrate. J Dairy Sci 95:3617–3628

    CAS  PubMed  Google Scholar 

  • Akgül T, Karakan T (2018) The role of probiotics in women with recurrent urinary tract infections. Turk J Urol 44(5):377–383

    PubMed  PubMed Central  Google Scholar 

  • Alaofè H, Burney J, Naylor R, Taren D (2017) Prevalence of anaemia, deficiencies of iron and vitamin A and their determinants in rural women and young children: a cross-sectional study in Kalalé district of northern Benin. Public Health Nutr 20(7):1203–1213

    PubMed  Google Scholar 

  • Aliakbarian B, Casale M, Paini M, Alberto CA (2015) Production of a novel fermented milk fortified with natural antioxidants and its analysis by NIR spectroscopy. LWT Food Sci Technol 61:376–383. https://doi.org/10.1016/j.lwt.2014.07.037

    Article  CAS  Google Scholar 

  • Allen L, de Benoist B, Dary O, Hurrell R (2006) WHO/FAO guidelines on food fortification with micronutrients. World Health Organization/Food and Agriculture Organization, Geneva

    Google Scholar 

  • Amirdivani S, Baba AS (2011) Changes in yogurt fermentation characteristics, and antioxidant potential and in vitro inhibition of Angiotensin-1 converting enzyme upon the inclusion of peppermint, dill and basil. LWT Food Sci Technol 44:1458–1464

    CAS  Google Scholar 

  • Anonymous (2018). https://www.businesswire.com/news/home/20160715005488/en/Global-Dairy-Based-Beverages-Market-Worth-USD. Published on July 15, 2016. Accessed 25 Aug 2019

  • Arslan S, Ozel S (2012) Some properties of stirred yoghurt made with processed grape seed powder, carrot juice or a mixture of grape seed powder and carrot juice. Milchwissenschaft 67:281–285

    CAS  Google Scholar 

  • Aryana K, Greenway F, Dhurandhar N, Tulley R, Finley J, Keenan M, Martin R, Pelkman C, Olson D, Zheng J (2015) A resistant-starch enriched yogurt: fermentability, sensory characteristics, and a pilot study in children. F1000Res 4:139

    PubMed  PubMed Central  Google Scholar 

  • Aryana KJ, Plauche S, Rao RM, McGrew P, Shah NP (2007) Fat-free plain yogurt manufactured with inulins of various chain lengths and Lactobacillus acidophilus. J Food Sci 72(3):M79–M84

    CAS  PubMed  Google Scholar 

  • Awasti N, Tomar SK, Pophaly SD, Lule VK, Singh TP, Anand S (2016) Probiotic and functional characterization of bifidobacteria of Indian human origin. J Appl Microbiol 120(4):1021–1032

    CAS  PubMed  Google Scholar 

  • Azad MAB, Sarker M, Li T, Yin J (2018) Probiotic species in the modulation of gut microbiota: an overview. Biomed Res Int 2018:9478630

    PubMed  PubMed Central  Google Scholar 

  • Azizkhani M, Tooryan F (2016) Antimicrobial activities of probiotic yogurts flavored with peppermint, basil, and zataria against Escherichia coli and Listeria monocytogenes. J Food Qual Hazards Control 3:79–86

    CAS  Google Scholar 

  • Bacher T, Køningsfeldt P (2000) WPI by microfiltration of skim milk. Scand Dairy Inf 3:18–20

    Google Scholar 

  • Barajas-Nava LA, Sánchez AC, Castilla-Peon M-F, Pizarro-Castellanos MP, Frias RV (2018) Probiotics for the treatment of irritable bowel syndrome in children. Cochrane Database Syst Rev 8:CD013095

    Google Scholar 

  • Barclay D (1998) Multiple fortification of beverages. Food Nutr Bull 19(2):168–171

    Google Scholar 

  • Bjarnason I, Sission G, Hayee B (2019) A randomised, double-blind, placebo-controlled trial of a multi-strain probiotic in patients with asymptomatic ulcerative colitis and Crohn’s disease. Inflammopharmacology 27(3):465–473

    CAS  PubMed  PubMed Central  Google Scholar 

  • Blanc B (1981) Biochemical aspects of human milk—comparison with bovinemilk. World Rev Nutr Diet 36:1

    CAS  PubMed  Google Scholar 

  • Boccio JR, Zubillaga MB, Caro RA, Gotelli CA, Gotelli MJ, Weill R (1996) Bioavailability and stability of microencapsulated ferrous sulphate in fluid milk: studies in mice. J Nutr Sci Vitaminol 42:233–236

    CAS  PubMed  Google Scholar 

  • Boehm G, Moro G (2008) Structural and functional aspects of prebiotics used in infant nutrition. J Nutr 138(9):1818S–1828S

    CAS  PubMed  Google Scholar 

  • Boeing H, Bechthold A, Bub A, Ellinger S, Haller D, Kroke A, Leschik-Bonnet E, Muller MJ, Oberritter H, Schulze M, Stehle P, Watzl B (2012) Critical review: vegetables and fruit in the prevention of chronic diseases. Eur J Nutr 51:637–663

    CAS  PubMed  PubMed Central  Google Scholar 

  • Bordoni A, Amaretti A, Leonardi A, Boschetti E, Danesi F, Matteuzzi D, Roncaglia L, Raimondi S, Rossi M (2013) Cholesterol-lowering probiotics: in vitro selection and in vivo testing of bifidobacteria. Appl Microbiol Biotechnol 9:8273–8281

    Google Scholar 

  • Bresnyan EW, Gadha RN (2018) Milk fortification in India: the journey so far. End poverty in South Asia, November 30, 2018. https://blogs.worldbank.org/endpovertyinsouthasia/milk-fortification-india-journey-sofar

  • Brückner-Gühmann M, Benthin A, Drusch S (2019) Enrichment of yoghurt with oat protein fractions: structure formation, textural properties and sensory evaluation. Food Hydrocoll 86:146–153

    Google Scholar 

  • Capela P, Hay TKC, Shah NP (2006) Effect of cryoprotectants, prebiotics and microencapsulation on survival of probiotic organisms in yoghurt and freeze-dried yoghurt. Food Res Int 39:203–211

    CAS  Google Scholar 

  • Cárdenas N, Calzada J, Peirotén Á, Jiménez E, Escudero R, Rodríguez JM, Medina M, Fernández L (2014) Development of a potential probiotic fresh cheese using two Lactobacillus salivarius strains isolated from human milk. BioMed Res Int 2014:801918

    PubMed  PubMed Central  Google Scholar 

  • Castillo NA, de Moreno de LeBlanc A, Galdeano CM, Perdigón G (2013) Comparative study of the protective capacity against Salmonella infection between probiotic and nonprobiotic Lactobacilli. J Appl Microbiol 114:861–876

    CAS  PubMed  Google Scholar 

  • Castro JM, Tornadijo ME, Fresno JM, Sandoval H (2015) Biocheese: a food probiotic carrier. Biomed Res Int 2015:723056

    CAS  PubMed  PubMed Central  Google Scholar 

  • Chen PW, Jheng TT, Shyu CL, Mao FC (2013) Synergistic antibacterial efficacies of the combination of bovine lactoferrin or its hydrolysate with probiotic secretion in curbing the growth of meticillin-resistant Staphylococcus aureus. J Med Microbiol 62:1845–1851

    PubMed  Google Scholar 

  • Chen Y-H, Tsai W-H, Wu H-Y, Chen C-Y, Yeh W-L, Chen Y-H, Hsu H-Y, Chen W-W, Chen Y-W, Chang W-W, Lin T-L, Lai H-C, Lin Y-H, Lai C-H (2019) Probiotic Lactobacillus spp. Act Against Helicobacter pylori-induced Inflammation. J Clin Med 8(1):90

    CAS  PubMed Central  Google Scholar 

  • Choi CH, Jo SY, Park HJ, Chang SK, Byeon JS, Myung SJ (2011) A randomized, double-blind, placebo-controlled multicenter trial of Saccharomyces boulardii in irritable bowel syndrome: effect on quality of life. J Clin Gastroenterol 45:679–683

    PubMed  Google Scholar 

  • Ciccarelli S, Stolfi I, Caramia G (2013) Management strategies in the treatment of neonatal and pediatric gastroenteritis. Infect Drug Resist 6:133–161

    PubMed  PubMed Central  Google Scholar 

  • Coman MM, Oancea AM, Verdenelli MC, Cecchini C, Bahrim GE, Orpianesi C, Cresci A, Silvi S (2017) Polyphenol content and in vitro evaluation of antioxidant, antimicrobial and prebiotic properties of red fruit extracts. Eur Food Res Technol 244(4):735–745

    Google Scholar 

  • Cortés-Zavaleta O, López-Malo A, Hernández-Mendoza A, García HS (2014) Antifungal activity of Lactobacilli and its relationship with 3-phenyllactic acid production. Int J Food Microbiol 173:30–35

    PubMed  Google Scholar 

  • Cosman F, De Beur S, LeBoff M, Lewiecki E, Tanner B, Randall S, Lindsay R (2014) Clinician’s guide to prevention and treatment of osteoporosis. Osteoporos Int 25(10):2359–2381

    CAS  PubMed  PubMed Central  Google Scholar 

  • Crevier B, Bélanger G, Vuillemard JC, St-Gelais D (2017) Short communication: production of cottage cheese fortified with vitamin D. J Dairy Sci 100(7):5212–5216

    CAS  PubMed  Google Scholar 

  • Crispín-Isidro G, Lobato-Calleros C, Espinosa-Andrews H, Alvarez-Ramirez J, Vernon-Carter EJ (2015) Effect of inulin and agave fructans addition on the rheological, microstructural and sensory properties of reduced-fat stirred yogurt. LWT Food Sci Technol 62:438–444

    Google Scholar 

  • Cueva C, Moreno-Arribas MV, Martin-Alvarez PJ, Bills G, Vicente MF, Basilio A, Lopez Rivas C, Requena T, Rodriguez JM, Bartolome B (2010) Antimicrobial activity of phenolic acids against commensal, probiotic and pathogenic bacteria. Res Microbiol 161:372–382

    CAS  PubMed  Google Scholar 

  • Dave RI, Shah NP (1998) Ingredient supplementation effects on viability of probiotic bacteria in yogurt. J Dairy Sci 81(11):2804–2816

    CAS  PubMed  Google Scholar 

  • de Paulo Farias D, de Araujo FF, Neri-Numa IA, Pastore GM (2019) Prebiotics: trends in food, health and technological applications. Trends Food Sci Tech 93:23–35

    Google Scholar 

  • De Souza EL, de Albuquerque TM, dos Santos AS, Massa NM, de Brito Alves JL (2018) Potential interactions among phenolic compounds and probiotics for mutual boosting of their health-promoting properties and food functionalities–a review. Crit Rev Food Sci Nutr 23:1–5

    CAS  Google Scholar 

  • DeFilippis AP, Sperling LS (2006) Understanding omega3’s. Am Heart J 151(3):564–570

    CAS  PubMed  Google Scholar 

  • Di Gioia D, Aloisio I, Mazzola G, Biavati B (2014) Bifidobacteria: their impact on gut microbiota composition and their applications as probiotics in infants. Appl Microbiol Biotechnol 98:563–577

    PubMed  Google Scholar 

  • Dinleyici EC, Eren M, Ozen M, Yargic ZA, Vandenplas Y (2012) Effectiveness and safety of Saccharomyces boulardii for acute infectious diarrhea. Expert Opin Biol Ther 12:395–410

    CAS  PubMed  Google Scholar 

  • Dirienzo DB (2014) Effect of probiotics on biomarkers of cardiovascular disease: implications for heart-healthy diets. Nutr Rev 72:18–29

    PubMed  Google Scholar 

  • Elleuch M, Bedigian D, Roiseux O, Besbes S, Blecker C, Attia H (2011) Dietary fibre and fibre-rich by-products of food processing: characterisation, technological functionality and commercial applications: a review. Food Chem 124(2):411–421

    CAS  Google Scholar 

  • Feyisetan O, Tracey C, Hellawell GO (2011) Probiotics, dendritic cells and bladder cancer. BJU Int 109:1594–1597

    PubMed  Google Scholar 

  • Foolad N, Armstrong AW (2014) Prebiotics and probiotics: the prevention and reduction in severity of atopic dermatitis in children. Benef Microbes 5(2):151–160

    CAS  PubMed  Google Scholar 

  • Fowler A, Toner M (2005) Cryo-injury and biopreservation. Ann N Y Acad Sci 1066:119–135

    CAS  PubMed  Google Scholar 

  • Fujiki H, Sueoka E, Watanabe T, Suganuma M (2015) Primary cancer prevention by green tea, and tertiary cancer prevention by the combination of green tea catechins and anticancer compounds. J Cancer Prev 20:1–4

    PubMed  PubMed Central  Google Scholar 

  • Gagada TH, Mutukumira AN, Narvhus JA, Feresu SB (1999) A review of traditional fermented foods and beverages of Zimbabwe. Int J Food Microbiol 53:1–11

    Google Scholar 

  • Ganesan B, Brothersen C, McMahon DJ (2011) Fortification of Cheddar cheese with vitamin D does not alter cheese flavor perception. J Dairy Sci 94:3708–3714

    CAS  PubMed  Google Scholar 

  • Gardiner G, Ross RP, Collins JK, Fitzgerald G, Stanton C (1998) Development of a probiotic cheddar cheese containing human-derived Lactobacillus paracasei strains. Appl Environ Microbiol 64(6):2192–2199

    CAS  PubMed  PubMed Central  Google Scholar 

  • Gastaldi E, Pellegrini O, Lagaude A, Tarodo De La Fuente B (1994) Functions of added calcium in acid milk coagulation. J Food Sci 59(2):310–312

    CAS  Google Scholar 

  • Gaur S, Waller AW, Andrade JE (2019) Effect of multiple micronutrient fortification on physico-chemical and sensory properties of chhash (traditional Indian yogurt-based drink). Foods 8:5. https://doi.org/10.3390/foods8010005

    Article  CAS  Google Scholar 

  • Gill CO (2006) Microbiology of frozen foods. In: Handbook of frozen food processing and packaging. CRC Press, Boca Raton

    Google Scholar 

  • Gionchetti P, Rizzello F, Venturi A, Brigidi P, Matteuzzi D, Bazzocchi G, Poggioli G, Miglioli M, Campieri M (2000) Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial. Gastroenterology 119(2):305–309

    CAS  PubMed  Google Scholar 

  • Godward G, Sultana K, Kailasapathy K, Peiris P, Arumugaswamy R, Reynolds N (2000) The importance of strain selection on the viability and survival of probiotic bacteria in dairy foods. Milchwissenschaft 55:441–445

    CAS  Google Scholar 

  • Goyal A, Sharma V, Sihag MK, Singh AK, Arora S, Sabikhi L (2016) Fortification of dahi (Indian yoghurt) with omega-3 fatty acids using microencapsulated flaxseed oil microcapsules. J Food Sci Technol 53(5):2422–2433

    CAS  PubMed  PubMed Central  Google Scholar 

  • Grattepanche F, Lacroix C (2013) Production of viable probiotic cells. In: McNeil B, Archer D, Giavasis I, Harvey L (eds) Microbial production of food ingredients, enzymes and nutraceuticals, 1st edn. Woodhead Publishing, Cambridge

    Google Scholar 

  • Hala MF, Ebtisam ED, Sanaa I, Badran MA, Marwa AS, Said ME (2010) Manufacture of low fat UF-soft cheese supplemented with rosemary extract (as natural antioxidant). J Am Sci 6:570–579

    Google Scholar 

  • Han J, Britten M, St-Gelais D, Champagne CP, Fustier P, Salmieri S, Lacroix M (2011) Polyphenolic compounds as functional ingredients in cheese. Food Chem 124:1589–1594

    CAS  Google Scholar 

  • Hanson AL, Metzger LE (2010) Evaluation of increased vitamin D fortification in high-temperature, short-time–processed 2% milk, UHT-processed 2% fat chocolate milk, and low-fat strawberry yogurt. J Dairy Sci 93:801–807

    CAS  PubMed  Google Scholar 

  • Harika R, Faber M, Samuel F, Kimiywe J, Mulugeta A, Eilander A (2017) Micronutrient status and dietary intake of iron, vitamin A, iodine, folate and zinc in women of reproductive age and pregnant women in Ethiopia, Kenya, Nigeria and South Africa: a systematic review of data from 2005 to 2015. Nutrients 9(10):1096

    PubMed Central  Google Scholar 

  • Heino AT, Uusi-Rauva J, Rantamaki PR, Tossavainen O (2007) Functional properties of native and cheese whey protein concentrate powders. Int Dairy J 60:277–285

    CAS  Google Scholar 

  • Holick M (2002) Vitamin D: the underappreciated D-lightful hormone that is important for skeletal and cellular health. Curr Opin Endocrinol Diabetes. 9(1):87–98

    CAS  Google Scholar 

  • Homayouni A, Bastani P, Ziyadi S, Mohammad-Alizadeh-Charandabi S, Ghalibaf M, Mortazavian AM, Mehrabany EV (2014) Effects of probiotics on the recurrence of bacterial vaginosis: a review. J Low Genit Tract Dis 18:79–86

    PubMed  Google Scholar 

  • Hoppe C, Andersen GS, Jacobsen S, Mølgaard C, Friis H, Sangild PT, Michaelsen KF (2008) The use of whey or skimmed milk powder in fortified blended foods for vulnerable groups. J Nutr 138(1):145S–161S

    CAS  PubMed  Google Scholar 

  • Hossain MN, Fakruddin M, Islam MN (2012) Development of fruit dahi (yoghurt) fortified with strawberry, orange and grapes juice. Am J Food Technol 7:562–570

    CAS  Google Scholar 

  • Hussein L, Gouda M, Fouad M, Labib E, Bassyouni R, Mohammad M (2014) Dietary intervention with yoghurt, synbiotic yogurt or traditional fermented sobya: bio-potency among male adolescents using five bio-markers of relevance to colonic metabolic activities. Food Nutr Sci 5(12):1131–1144

    CAS  Google Scholar 

  • Indrio F, Di Mauro A, Riezzo G, Civardi E, Intini C, Corvaglia L, Ballardini E, Bisceglia M, Cinquetti M, Brazzoduro E, Del Vecchio A, Tafuri S, Francavilla R (2014) Prophylactic use of a probiotic in the prevention of colic, regurgitation, and functional constipation: a randomized clinical trial. JAMA Pediatr 168(3):228–233

    PubMed  Google Scholar 

  • International Food Policy Research Institute (2016) Global nutrition 2016: from promise to impact: ending malnutrition by 2030. IFPRI, Washington

    Google Scholar 

  • International Scientific Association for Probiotics and Prebiotics (ISAPP) (2016). https://isappscience.org/. Accessed 26 Sep 2019

  • Irvine SL, Hekmat S (2011) Evaluation of sensory properties of probiotic yogurt containing food products with prebiotic fibres in Mwanza, Tanzania. Food Nutr Sci 2(5):434

    CAS  Google Scholar 

  • Jacobs SE, Tobin JM, Opie GF, Donath S, Tabrizi SN, Pirotta M, Morley CJ, Garland SM, ProPrems Study Group (2013) Probiotic effects on late-onset sepsis in very preterm infants: a randomized controlled trial. Pediatrics 132(6):1055–1062

    PubMed  Google Scholar 

  • Janvier A, Malo J, Barrington KJ (2014) Cohort study of probiotics in a North American neonatal intensive care unit. J Pediatr 164(5):980–985

    PubMed  Google Scholar 

  • Jay JM, Loessner MJ, Golden DA (2005) Modern food microbiology. Springer Science & Business Media, Berlin

    Google Scholar 

  • Jayalalitha V, Balasundaram B, Palanidorai, Naresh KC (2012) Fortification off encapsulated iron in probiotic yoghurt. Int J Agric Res Rev 2:80–84

    CAS  Google Scholar 

  • Johnston BC, Goldenberg JZ, Vandvik PO, Sun X, Guyatt GH (2011) Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev 11:CD004827

    Google Scholar 

  • Joint Food and Agriculture Organization of The United Nations/World Health Organization FAO/WHO (1994) Codex Alimentarius comission. CL 1994/10-MAS May 1994

    Google Scholar 

  • Jones EL, Shingfield KJ, Kohen C, Jones AK, Lupoli B, Grandison AS, Beever DE, Williams CM, Calder PC, Yaqoob P (2005) Chemical, physical, and sensory properties of dairy products enriched with conjugated linoleic acid. J Dairy Sci 88(8):2923–2937

    CAS  PubMed  Google Scholar 

  • Kahraman O, Ustunol Z (2012) Effect of zinc fortification on Cheddar cheese quality. J Dairy Sci 95:2840–2847

    CAS  PubMed  Google Scholar 

  • Kailasapathy K, Harmstorf I, Phillips M (2008) Survival of Lactobacillus acidophilus and Bifidobacterium animalis ssp lactis in stirred fruit yogurts. LWT Food Sci Technol 41:1317–1322

    CAS  Google Scholar 

  • Karaaslan M, Ozden M, Vardin H, Turkoglu H (2011) Phenolic fortification of yogurt using grape and callus extracts. LWT Food Sci Technol 44:1065–1072

    CAS  Google Scholar 

  • Kim K-T, Hwang JE, Eum SJ, Paik H-D (2019) Physiochemical analysis, antioxidant effects, and sensory characteristics of quark cheese supplemented with ginseng extract. Food Sci Anim Res 39(2):324–331

    Google Scholar 

  • Kinsella JE, Whitehead DM (1989) Proteins in whey: chemical, physical, and functional properties. Adv Food Nutr Res 33:343–438

    CAS  PubMed  Google Scholar 

  • Kris-Etherton PM, Grieger JA, Etherton TD (2009) Dietary reference intakes for DHA and EPA. Prostaglandins Leukot Essent Fatty Acids 81(2–3):99–104

    CAS  PubMed  Google Scholar 

  • Kumar A, Kumar D (2016) Development of antioxidant rich fruit supplemented probiotic yogurts using free and microencapsulated Lactobacillus rhamnosus culture. J Food Sci Technol 53:667–675

    CAS  PubMed  Google Scholar 

  • Kumar ST, Arvindakshan P, Sangeetha A, Pagote CN, Rao KJ (2013) Development of mint flavoured yoghurt spread. Asian J Dairy Food Res 32(1):19–24

    Google Scholar 

  • Lane KE, Derbyshire EJ (2018) Omega-3 fatty acids—a review of existing and innovative delivery methods. Crit Rev Food Sci Nutr 58(1):62–69

    CAS  PubMed  Google Scholar 

  • Lavie CJ, Milani RV, Mehra MR, Ventura HO (2009) Omega-3 polyunsaturated fatty acids and cardiovascular diseases. J Am Coll Cardiol 54(7):585–594

    CAS  PubMed  Google Scholar 

  • Lee HC, Jenner AM, Low CS, Lee YK (2006) Effect of tea phenolics and their aromatic fecal bacterial metabolites on intestinal. Res Microbiol 157:876–884

    CAS  Google Scholar 

  • Li D, Rosito G, Slagle T (2013) Probiotics for the prevention of necrotizing enterocolitis in neonates: an 8-year retrospective cohort study. J Clin Pharm Ther 38:445–449

    CAS  PubMed  Google Scholar 

  • Licciardi PV, Ismail IH, Balloch A, Mui M, Hoe E, Lamb K, Tang ML (2013) Maternal supplementation with LGG reduces vaccine-specific immune responses in infants at high-risk of developing allergic disease. Front Immunol 4:381

    PubMed  PubMed Central  Google Scholar 

  • Long J, Yang J, Henning SM, Woo SL, Hsu M, Chan B, Heber D, Li Z (2019) Xylooligosaccharide supplementation decreases visceral fat accumulation and modulates cecum microbiome in mice. J Funct Foods 52:138–146

    CAS  Google Scholar 

  • Lu Y, McMahon DJ, Vollmer AH (2016) Investigating rennet coagulation properties of recombined highly concentrated micellar casein concentrate and cream for use in cheese making. J Dairy Sci 100:892–900

    PubMed  Google Scholar 

  • Luoto R, Ruuskanen O, Waris M, Kalliomäki M, Salminen S, Isolauri E (2013) Prebiotic and probiotic supplementation prevents rhinovirus infections in preterm infants: a randomized, placebo-controlled trial. J Allergy Clin Immunol 133:405–413

    PubMed  PubMed Central  Google Scholar 

  • Lynch SR, Cook JD (1980) Interaction of vitamin C and iron. Ann N Y Acad Sci 355:32–44

    CAS  PubMed  Google Scholar 

  • Maldonado Galdeano C, Cazorla SI, Lemme Dumit JM, Vélez E, Perdigón G (2019) Beneficial effects of probiotic consumption on the immune system. Ann Nutr Metab 74(2):115–124

    CAS  PubMed  Google Scholar 

  • Marafon AP, Sumi A, Alcântara MR, Tamime AY, de Oliveira N (2011) Optimization of the rheological properties of probiotic yoghurts supplemented with milk proteins. LWT Food Sci Technol 44:511–519

    CAS  Google Scholar 

  • Maurya VK, Aggarwal M (2019) Fabrication of nano-structured lipid carrier for encapsulation of vitamin D3 for fortification of ‘Lassi’; A milk based beverage. J Steroid Biochem Mol Biol 193:105429

    CAS  PubMed  Google Scholar 

  • Mayengbam S, Lambert JE, Parnell JA, Tunnicliffe JM, Nicolucci AC, Han J, Sturzenegger T, Shearer J, Mickiewicz B, Vogel HJ, Madsen KL, Reimer RA (2019) Impact of dietary fiber supplementation on modulating microbiota–host–metabolic axes in obesity. J Nutr Biochem 64:228–236

    CAS  PubMed  Google Scholar 

  • McCowen KC, Ling PR, Decker E, Djordjevic D, Roberts RF, Coupland JN, Bistrian BR (2010) A simple method of supplementation of omega-3 polyunsaturated fatty acids: use of fortified yogurt in healthy volunteers. Nutr Clin Pract 25(6):641–645

    PubMed  PubMed Central  Google Scholar 

  • McFarland LV (2007) Meta-analysis of probiotics for the prevention of traveler’s diarrhea. Travel Med Infect Dis 5:97–105

    PubMed  Google Scholar 

  • Mehar-Afroz Q, Swaminathan K, Karthikeyan P, Pervez K, Umesh M (2012) Application of nanotechnology in food and dairy processing: an overview. Pak J Food Sci 22(1):23–31

    Google Scholar 

  • Meyer KM, Engevik M, Aagaard K (2019) Human milk oligosaccharides (HMOs) promote growth of commensal Streptococcus spp. abundant in human milk. Am J Obstet Gynecol 220(Suppl 1):S605–S606

    Google Scholar 

  • Michaëlsson K, Wolk A, Lemming EW, Melhus H, Byberg L (2018) Intake of milk or fermented milk combined with fruit and vegetable consumption in relation to hip FractureRates: a cohort study of Swedish women. J Bone Miner Res 33(3):449–457

    PubMed  Google Scholar 

  • Minj J, Vij S (2017) Effect of prebiotic inulin on the fermentation and growth kinetics pattern of probiotic yoghurt bacteria. Int J Curr Microbiol App Sci 6(12):1755–1768

    Google Scholar 

  • Moro-García MA, Alonso-Arias R, Baltadjieva M, Fernández Benítez C, Fernández Barrial MA, Díaz Ruisánchez E, Alonso Santos R, Alvarez Sánchez M, Saavedra Miján J, López-Larrea C (2013) Oral supplementation with Lactobacillus delbrueckii subsp. bulgaricus 8481 enhances systemic immunity in elderly subjects. Age (Dordr) 35:1311–1326

    Google Scholar 

  • Mozaffarian D, Hao T, Rimm EB, Willett WC, Hu FB (2011) Changes in diet and lifestyle and long-term weight gain in women and men. N Engl J Med 364:2392–2404

    CAS  PubMed  PubMed Central  Google Scholar 

  • Mozaffarian D (2016) Dietary and policy priorities for cardiovascular disease, diabetes, and obesity: a comprehensive review. Circulation 133:187–225

    CAS  PubMed  PubMed Central  Google Scholar 

  • Najgebauer-Lejko D, Sady M, Grega T, Walczycka M (2011) The impact of tea supplementation on microflora, pH and antioxidant capacity of yoghurt. Int Dairy J 21:568–574

    CAS  Google Scholar 

  • Ndabikunze BK, Mumba FG, Ngowi H, Chove L, Mongi R, Abdulsud I (2017) Development and sensory evaluation of yoghurt flavoured with solar dried fruits. J Agric Sci Food Technol 3:125–131

    Google Scholar 

  • Nualkaekul S, Salmeron I, Charalampopoulos D (2011) Investigation of the factors influencing the survival of Bifidobacterium longum in model acidic solutions and fruit juices. Food Chem 129:1037–1044

    CAS  PubMed  Google Scholar 

  • Ortiz L, Ruiz F, Pascual L, Barberis L (2014) Effect of two probiotic strains of Lactobacillus on in vitro adherence of Listeria monocytogenes, Streptococcus agalactiae, and Staphylococcus aureus to vaginal epithelial cells. Curr Microbiol 68(6):679–684

    CAS  PubMed  Google Scholar 

  • Ozer B, Kirmaci HA, Senel E, Atamer M, Hayaloglu A (2009) Improving the viability of Bifidobacterium bifidum BB-12 and Lactobacillus acidophilus LA-5 in white-brined cheese by microencapsulation. Int Dairy J 19(1):22–29

    Google Scholar 

  • Pacheco-Ordaz R, Wall-Medrano A, Goñi MG, Ramos-Clamont-Montfort G, Ayala-Zavala JF, González-Aguilar GA (2018) Effect of phenolic compounds on the growth of selected probiotic and pathogenic bacteria. Lett Appl Microbiol 66(1):25–31

    CAS  PubMed  Google Scholar 

  • Panwar H, Calderwood D, Grant IR, Grover S, Green BD (2014) Strains isolated from infant faeces possess potent inhibitory activity against intestinal alpha- and beta-glucosidases suggesting anti-diabetic potential. Eur J Nutr 53(7):1465–1474

    CAS  Google Scholar 

  • Parraga-Martinez I, Lopez-Torres-Hidalgo JD, Campo-Del Campo JM, Galdon-Blesa MP, Precioso-Yanez JC, Rabanales-Sotos J, Garcia-Reyes-Ramos M, Andres-Pretel F, Navarro-Bravo B, Lloret-Callejo A (2015) Long-term effects of plant stanols on the lipid profile of patients with hypercholesterolemia. A randomized clinical trial. Rev Esp Cardiol 68(8):665–671

    PubMed  Google Scholar 

  • Peterson DM (2011) Storage proteins. In: Oats: chemistry and technology. AACC International, Inc., St. Paul, pp 123–142

    Google Scholar 

  • Phavichitr N, Puwdee P, Tantibhaedhyangkul R (2013) Cost-benefit analysis of the probiotic treatment of children hospitalized for acute diarrhea in Bangkok, Thailand. Southeast Asian J Trop Med Public Health 44:1065–1071

    PubMed  Google Scholar 

  • Preedy VR, Srirajaskanthan R, Patel VB (2013) Handbook of food fortification and health. Humana Press, New York

    Google Scholar 

  • Provost V, Lamantia V, Bissonnette S, Cyr Y, Faraj M (2019) Increased fiber intake predicts the decrease in 2nd phase glucose-induced hyperinsulinemia following a hypocaloric diet in obese subjects. Nutr Metab Cardiovasc Dis 29(5):504–512

    CAS  PubMed  Google Scholar 

  • Putta S, Yarla NS, Lakkappa DB, Imandi SB, Malla RR, Chaitanya AK, Chari BPV, Saka S, Vechalapu RR, Kamal MA, Tarasov VT, Chubarev VN, Kumar KS, Aliev G (2018) Probiotics: supplements, food, pharmaceutical industry. In: Grumezescu A, Holban AM (eds) Therapeutic, probiotic, and unconventional foods, 1st edn. Academic, Cambridge

    Google Scholar 

  • Ramai D, Noorani A, Ofosu A, Ofori E, Reddy M, Gasperino J (2019) Practice measures for controlling and preventing hospital associated Clostridium difficile infections. Hosp Pract 47(3):123–129

    Google Scholar 

  • Robison N (2015) Stay active in old age—dairy targets the elderly. http://www.nutraingredients.com/Suppliers2/Food-firm-targets-elderly

  • Rodriguez EB, Flavier ME, Rodriguez-Amaya DB, Amaya-Farfán J (2006) Phytochemicals and functional foods. Current situation and prospect for developing countries. Segurança Alimentar e Nutricional Campinas 13:1–22

    Google Scholar 

  • Ruhee D, Mahomoodally F (2015) Relationship between family meal frequency and individual dietary intake among diabetic patients. J Diabetes Metab Disord 14:66

    PubMed  PubMed Central  Google Scholar 

  • Sagdic O, Ozturk I, Cankurt H, Tornuk F (2012) Interaction between some phenolic compounds and probiotic bacterium in functional ice cream production. Food Bioprocess Technol 5:2964–2971

    CAS  Google Scholar 

  • Salo P, Kuusisto P (2016) Cholesterol lowering effect of plant stanol ester yoghurt drinks with added camelina oil. Cholesterol 2016:5349389

    PubMed  PubMed Central  Google Scholar 

  • Santillan-Urquiza E, Mendez-Rojas MA, Velez-Ruiz JF (2017) Fortification of yogurt with nano and micro sized calcium, iron and zinc, effect on the physicochemical and rheological properties. LWT 80:462–469

    CAS  Google Scholar 

  • Saxena M, Saxena J, Nema R, Singh D, Gupta A (2013) Phytochemistry of medicinal plants. J Pharmacogn Phytochem 1:168–182

    Google Scholar 

  • Schutyser MAI, Perdana J, Boom RM (2012) Single droplet drying for optimal spray drying of enzymes and probiotics. Trends Food Sci Technol 27:73–82

    CAS  Google Scholar 

  • Schwarzer M, Srutkova D, Schabussova I, Hudcovic T, Akgün J, Wiedermann U, Kozakova H (2013) Neonatal colonization of germ-free mice with Bifidobacterium longum prevents allergic sensitization to major birch pollen allergen Bet v 1. Vaccine 31:5405–5412

    CAS  PubMed  Google Scholar 

  • Shan LS, Hou P, Wang ZJ, Liu FR, Chen N, Shu LH, Zhang H, Han XH, Han XX, Cai XX, Shang YX, Vandenplas Y (2013) Prevention and treatment of diarrhoea with Saccharomyces boulardii in children with acute lower respiratory tract infections. Benefic Microbes 4(4):329–334

    Google Scholar 

  • Shida K, Nomoto K (2013) Probiotics as efficient immunopotentiators: translational role in cancer prevention. Indian J Med Res 138:808–814

    CAS  PubMed  PubMed Central  Google Scholar 

  • Shori AB, Baba AS (2011a) Antioxidant activity and inhibition of key enzymes linked to type-2 diabetes and hypertension by Azadirachta indica-yogurt. J Saudi Chem Soc 17:295–301

    Google Scholar 

  • Shori AB, Baba AS (2011b) Comparative antioxidant activity, proteolysis and in vitro a-amylase and a-glucosidase inhibition of Allium sativum-yogurts made from cow and camel milk. J Saudi Chem Soc 18:456–463

    Google Scholar 

  • Singh G, Arora S, Sharma GS, Sindhu JS, Kansal VK, Sangwan RB (2007) Heat stability and calcium bioavailability of calcium-fortified milk. LWT Food Sci Technol 40:625–631

    CAS  Google Scholar 

  • Soto-Méndez MJ, Rangel-Huerta OD, Ruiz-López MD, de Victoria EM, Anguita-Ruiz A, Gil A (2019) Role of functional fortified dairy products in cardiometabolic health: a systematic review and meta-analyses of randomized clinical trials. Adv Nutr 10(2):S251–S271

    PubMed  PubMed Central  Google Scholar 

  • Spiro A, Buttriss JL (2014) Vitamin D: an overview of vitamin D status and intake in Europe. Nutr Bull 39(4):322–350

    CAS  PubMed  PubMed Central  Google Scholar 

  • Stanton C, Gardiner G, Lynch PB, Collins JK, Fitzgerald G, Ross RP (1998) Probiotic cheese. Int Dairy J 8:491–496

    CAS  Google Scholar 

  • Svanborg S, Johansen AG, Abrahamsen RK, Skeie SB (2015) The composition and functional properties of whey protein concentrates produced from buttermilk are comparable with those of whey protein concentrates produced from skimmed milk. J Dairy Sci 98(9):5829–5840

    CAS  PubMed  Google Scholar 

  • Szajewska H, Mrukowicz J (2005) Meta-analysis: non-pathogenic yeast Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea. Aliment Pharmacol Ther 22:365–372

    CAS  PubMed  Google Scholar 

  • Szajewska H, Urbańska M, Chmielewska A, Weizman Z, Shamir R (2014) Meta-analysis: Lactobacillus reuteri strain DSM 17938 (and the original strain ATCC 55730) for treating acute gastroenteritis in children. Benefic Microbes 5(3):285–293

    CAS  Google Scholar 

  • Teixeira PC, Castro MH, Malcata FX, Kirby RM (1995) Survival of Lactobacillus delbrueckii ssp. bulgaricus following spray-drying. J Dairy Sci 78:1025–1031

    CAS  Google Scholar 

  • Tomaro-Duchesneau C, Saha S, Malhotra M, Jones ML, Labbé A, Rodes L, Kahouli I, Prakash S (2014) Effect of orally administered L. fermentum NCIMB 5221 on markers of metabolic syndrome: an in vivo analysis using ZDF rats. Appl Microbiol Biotechnol 98:115–126

    CAS  PubMed  Google Scholar 

  • Upadhyay N, Goyal A, Kumar A, Ghai DL, Singh R (2014) Preservation of milk and milk products for analytical purposes. Food Rev Int 30:203–224

    CAS  Google Scholar 

  • US Department of Health and Human Services Agency for Healthcare Research and Quality (2016) Omega-3 fatty acids and cardiovascular disease: an updated systematic review. Systematic review. Published on August 12, 2016. https://effectivehealthcare.ahrq.gov/products/fatty-acids-cardiovascular-disease/research. Accessed 27 Jan 2020

  • Ustunol AA (2018) Effect of microencapsulated ferrous sulfate particle size on Cheddar cheese composition and quality. J Dairy Sci 10(8):6814–6822

    Google Scholar 

  • Van der Beek CM, Canfora EE, Kip AM, Gorissen SHM, Olde Damink SWM, van Eijk HM, Holst JJ, Blaak EE, Dejong CHC, Lenaerts K (2018) The prebiotic inulin improves substrate metabolism and promotes short-chain fatty acid production in overweight to obese men. Metabolism 87:25–35

    PubMed  Google Scholar 

  • Vasile A, Miron TL, Paraschiv D, Bahrim G, Dima S (2011) The enhancement of the growth ability and the viability of some probiotic bacteria in media with wild Origanum vulgare L. extract. Rom Biotechnol Lett 16(6):6847–6853

    CAS  Google Scholar 

  • Vieira AT, Teixeira MM, Martins FS (2012) The role of probiotics and prebiotics in inducing gut immunity. Front Immunol 4:445

    Google Scholar 

  • Wagner D, Rousseau D, Sidhom G, Pouliot M, Audet P, Vieth R (2008) Vitamin D3 fortification, quantification, and long-term stability in Cheddar and low-fat cheeses. J Agric Food Chem 56:7964–7969

    CAS  PubMed  Google Scholar 

  • Wang S, Moustaid-Moussa N, Chen L, Mo H, Shastri A, Su R (2014) Novel insights of dietary polyphenols and obesity. J Nutr Biochem 25:1–18

    PubMed  PubMed Central  Google Scholar 

  • Weber PC, Leaf A (1991) Cardiovascular effects of omega 3 fatty acids. Atherosclerosis risk factor modification by omega 3 fatty acids. World Rev Nutr Diet 66:218–232

    CAS  PubMed  Google Scholar 

  • Weber PC (1989) Clinical studies on the effects of n-3 fatty acids on cells and eicosanoids in the cardiovascular system. J Intern Med Suppl 225(731):61–68

    Google Scholar 

  • WHO (2018). https://www.who.int/news-room/fact-sheets/detail/malnutrition. Published on 16 Feb 2018

  • Wickens K, Stanley TV, Mitchell EA, Barthow C, Fitzharris P, Purdie G, Siebers R, Black PN, Crane J (2013) Early supplementation with Lactobacillus rhamnosus HN001 reduces eczema prevalence to 6 years: does it also reduce atopic sensitization? Clin Exp Allergy 43:1048–1057

    CAS  PubMed  Google Scholar 

  • Wood AD, Strachan AA, Thies F, Aucott LS, Reid DM, Hardcastle AC, Mavroeidi A, Simpson WG, Duthie GG, Macdonald HM (2014) Patterns of dietary intake and serum carotenoid and tocopherol status are associated with biomarkers of chronic low-grade systemic inflammation and cardiovascular risk. Br J Nutr 112:1341–1352

    CAS  PubMed  Google Scholar 

  • Wright K, Wright H, Murray M (2015) Probiotic treatment for the prevention of antibiotic-associated diarrhoea in geriatric patients: a multicentre randomised controlled pilot study. Australas J Ageing 34(1):38–42

    PubMed  Google Scholar 

  • Wu B, Yu Q, Chang S, Pedroso MM, Gao Z, He B, Schenk G (2019a) Expansin assisted bio-affinity immobilization of endoxylanase from Bacillus subtilis onto corncob residue: characterization and efficient production of xylooligosaccharides. Food Chem 282:101–108

    CAS  PubMed  Google Scholar 

  • Wu RY, Li B, Koike Y, Maattanen P, Miyake H, Cadete M, Johnson-Henry KC, Botts SR, Lee C, Abrahamsson TR, Landberg E, Pierro A, Sherman PM (2019b) Human milk oligosaccharides increase mucin expression in experimental necrotizing enterocolitis. Mol Nutr Food Res 63:1800658

    Google Scholar 

  • Wu ZJ, Du X, Zheng J (2013) Role of Lactobacillus in the prevention of Clostridium difficile-associated diarrhea: a meta-analysis of randomized controlled trials. Chin Med J (Engl.) 126:4154–4161

    Google Scholar 

  • Xie X, He Y, Li H, Yu D, Na L, Sun T, Zhang D, Shi X, Xia Y, Jiang T, Rong S, Yang S, Ma X, Xu G (2019) Effects of prebiotics on immunologic indicators and intestinal microbiota structure in perioperative colorectal cancer patients. Nutrition 61:132–142

    CAS  PubMed  Google Scholar 

  • Yerlikaya O, Ender G, Torunoglu FA, Akbulut N (2013) Production of probiotic milk drink containing Lactobacillus acidophilus, Bifidobacterium animalis subsp. lactis and Lactobacillus casei. Agro Food Industry Hi Tech

    Google Scholar 

  • Yu H, Liu L, Chang Z, Wang S, Wen B, Yin P, Liu D, Chen B, Zhang J (2013) Genome sequence of the bacterium Bifidobacterium longum strain CMCC P0001, a probiotic strain used for treating gastrointestinal disease. Genome Announc 1(5):e00716–e00713

    PubMed  PubMed Central  Google Scholar 

  • Yu J, Zhang W, Zhang R, Ruan X, Ren P, Lu B (2015) Lactulose accelerates liver regeneration in rats by inducing hydrogen. J Surg Res 195(1):128–135

    CAS  PubMed  Google Scholar 

  • Zahedirad M, Asadzadeh S, Nikooyeh B, Neyestani TR, Khorshidian N, Yousefi M, Mohammad MA (2019) Fortification aspects of vitamin D in dairy products: a review study. Int Dairy J 94:53–64

    CAS  Google Scholar 

  • Zayed MG, Hickman SJ, Batty R, McCloskey EV, Pepper IM (2015) Unilateral compressive optic neuropathy due to skull hyperostosis secondary to nutritional vitamin A deficiency. Clin Cases Miner Bone Metab 12(1):75

    PubMed  PubMed Central  Google Scholar 

  • Zhou Y, Zheng J, Li Y, Xu DP, Li S, Chen YM, Li HB (2016) Natural polyphenols for prevention and treatment of cancer. Nutrients 8(8):515

    PubMed Central  Google Scholar 

Websites

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jagrani Minj .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Minj, J., Dogra, S. (2020). Significance of Fortification of Beneficial Natural Ingredients in Milk and Milk Products. In: Minj, J., Sudhakaran V, A., Kumari, A. (eds) Dairy Processing: Advanced Research to Applications. Springer, Singapore. https://doi.org/10.1007/978-981-15-2608-4_5

Download citation

Publish with us

Policies and ethics