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Citric acid and polyols production by Aspergillus niger at high glucose concentration in solid state fermentation on inert support

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Summary

Aspergillus niger cultures at high initial glucose concentration (up to 400 g/1) on Amberlite as inert support were carried out. Citric acid was accumulated in the support showing high concentration (94.54 g/l) and productivity (1.35 g/l h) without inhibition related to the presence of metals (Mn2+, Zn2+, Co2+, Cu2+, and Ca2+) at high concentrations. Citric acid accumulation was clearly associated with both, glycerol production and to the age of the culture. Glycerol and erythritol, the major osmoregulator metabolites, were also produced (8.16 and 24.57 g/l respectively) at 400 g/l of glucose.

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References

  • Acuña-Argüelles, M., Gutiérrez-Rojas, M., Viniegra-González, G. Favela-Torres, E. (1994). Biotechnol. Lett. 16: 23–28.

    Google Scholar 

  • Auria, R., Hernández, S., Raimbault, M., Revah, S. (1990). Biotechnol. Techniques, 4: 391–396.

    Google Scholar 

  • Auria, R., Morales, M., Villegas, E. Revah, S. (1993). Biotechnol. Bioeng. 41: 1007–1013.

    Google Scholar 

  • Bloomberg, A., Adler, L. (1992). Advances in Microbial Physiology. 33: 145–212.

    Google Scholar 

  • Bradford, M. M. (1976). Anal. Biochem. 72: 248–254.

    Google Scholar 

  • Brown, A.D. 1978. In Advances in Microbial Physiology. Ed. A.H. Rose J.G. Morris. Academic Press, London-New York. 17: 181–242.

    Google Scholar 

  • Clutterbuck, A. J. (1974). In Handbook of genetics. Ed. Plenum Pub., New York, USA.

    Google Scholar 

  • Eikmeier, H. Rehm H. J. (1984). Appl. Microbiol. Biotechnol. 20: 365–375.

    Google Scholar 

  • Hang, Y. D., Woodams, E. E. 1987. Biotechnol. Lett., 9: 183–186.

    Google Scholar 

  • Kirimura, K., Sarangbin, S., Rugsaseel, S. Usami, S. (1992). Appl. Microbiol. Biotechnol. 36: 573–577.

    Google Scholar 

  • Kristiansen, B., Sinclair, C.G. (1979). Biotechnol. Bioeng. 21: 297–315.

    Google Scholar 

  • Kubicek, C. P., Röhr, M. (1985). Appl. Envir. Microb. 50: 1336–1338.

    Google Scholar 

  • Lakshminarayana, K., Chaudhary, K., Ethiraj, S., Tauro, P. (1975). Biotechnol. Bioeng. 17: 291–293.

    Google Scholar 

  • Lee, Y.H., Lee, C.W. Chang, N.H. (1989). Appl. Microbiol. Biotechnol. 30: 141–143.

    Google Scholar 

  • Legiša, M. Mattey, M. (1986a). Enzime Microb. Technol. 8, 258–259.

    Google Scholar 

  • Legiša, M. Mattey, M. (1986b). Enzime Microb. Technol. 8, 607–609.

    Google Scholar 

  • Mattey, M. (1992). Crit. Rev. Biotechnol. 12, 87–112.

    Google Scholar 

  • Pandey A., (1992). Process Biochem. 27:109–117.

    Google Scholar 

  • Ruokas, T., Kotzekidou, P. (1987). Enzime Microb. Technol. 9: 291–294.

    Google Scholar 

  • Solís P. S. E., Favela-Torres E., Viniegra-González G. Gutiérrez-Rojas M. (1993). J. Appl. Microbiol. Biotechnol. 39: 36–41.

    Google Scholar 

  • Xu, D. B., Madrid, C.P. Röhr, M. and Kubicek, C.P. (1986) Appl. Microbiol. Biotechnol. 30, 553–561

    Google Scholar 

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Gutiérrez-Rojas, M., Córdova, J., Auria, R. et al. Citric acid and polyols production by Aspergillus niger at high glucose concentration in solid state fermentation on inert support. Biotechnol Lett 17, 219–224 (1995). https://doi.org/10.1007/BF00127992

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