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A model for multiproduct-inhibited growth of Enterobacter aerogenes in 2,3-butanediol fermentation

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Summary

Ethanol is identified as a strongly inhibitory metabolite in addition to acetic acid and 2,3-butanediol in 2,3-butanediol production by Enterobacter aerogenes. A model is proposed to describe the multiproduct-inhibited growth of E. aerogenes in 2,3-butanediol fermentation. The model is verified with data from anaerobic and microaerobic continuous culture. On the basis of this model the difference in biomass production and product patterns during anaerobic and microaerobic growth of E. aerogenes is discussed.

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Authors and Affiliations

  1. Biochemical Engineering Division, GBF — National Research Institute for Biotechnology, Mascheroder Weg 1, W-3300, Braunschweig, Federal Republic of Germany

    An-Ping Zeng & Wolf-Dieter Deckwer

Authors
  1. An-Ping Zeng
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  2. Wolf-Dieter Deckwer
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Offprint requests to: W.-D. Deckwer

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Zeng, AP., Deckwer, WD. A model for multiproduct-inhibited growth of Enterobacter aerogenes in 2,3-butanediol fermentation. Appl Microbiol Biotechnol 35, 1–3 (1991). https://doi.org/10.1007/BF00180625

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  • DOI: https://doi.org/10.1007/BF00180625

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