Abstract
The neuropeptide substance P (SP) was injected into the region of the nucleus basalis magnocellularis (NBM). The influence of SP on the performance of the single trial “uphill avoidance task” was tested. The post-trial injection of 1 ng SP (in 0.5 μl volume) led to significantly longer latencies in the uphill response. This result can be interpreted in terms of a facilitating effect of SP on performance of an inhibitory avoidance response.
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Kafetzopoulos, E., Holzhäuer, M.S. & Huston, J.P. Substance P injected into the region of the nucleus basalis magnocellularis facilitates performance of an inhibitory avoidance task. Psychopharmacology 90, 281–283 (1986). https://doi.org/10.1007/BF00181260
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DOI: https://doi.org/10.1007/BF00181260