Skip to main content
Log in

The closely linked genes encoding the myeloid nuclear differentiation antigen (MNDA) and IFI16 exhibit contrasting haemopoietic expression

  • Brief Communication
  • Published:
Immunogenetics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Briggs, J. A., Burrus, G. R., Stickney, B. D., and Briggs, R. C. Cloning and expression of the human myeloid cell nuclear differentiation antigen: regulation by interferon α. J Cell Biochem 49: 82–92, 1992

    Google Scholar 

  • Briggs, R. C., Dworkin, L., Briggs, J., Dessypris, E., Stein, J., Stein, G., and Lian, G. Interferon-α selectively affects expression of the human myeloid cell nuclear differentiation antigen in late stage cells in the monocytic but not the granulocytic lineage. J Cell Biochem 54: 198–206, 1994a

    Google Scholar 

  • Briggs, R. C., Briggs, J. A., Ozer, J., Sealy, L., Dworkin, L. L., Kingsmore, S. F., Seldin, M. F., Kaur, G. P., Athwal, R. S., and Dessypris, E. N. The human myeloid cell nuclear differentiation antigen gene is one of at least two related interferon-inducible genes located at chromosome 1q that are expressed specifically in hematopoietic cells. Blood 83: 2153–2162, 1994b

    Google Scholar 

  • Callen, D. F., Baker, E., Eyre, H. J., Chernos, J. E., Bell, J. A., and Sutherland, G. R. Reassessment of two apparent deletions of chromosome 16p to an ins(11: 16) and a t(1 : 16) by chromosome painting. Ann Génét 33: 219–221, 1990

    Google Scholar 

  • Choubey, D. and Lengyel, P. Interferon action: nucleolar and nucleoplasmic localization of the interferon-inducible 72-kDa protein that is encoded by the Ifi 204 gene from the Gene 200 cluster. J Cell Biol 116: 1333–1341, 1992

    Google Scholar 

  • Choubey, D. and Lengyel, P. Interferon action: Cytoplasmic and nuclear localization of the interferon-inducible 52-kDa protein that is encoded by the Ifi 202 gene from the Gene 200 cluster. J Interferon Res 13: 43–52, 1993

    Google Scholar 

  • Choubey, D., Snoddy, J., Chaturvedi, V., Toniato, E., Opdenakker, G., Thakur, A., Samanta, H., Engel, D. A., and Lengyel, P. Interferons as gene activators: indications for repeated gene duplication during the evolution of a cluster of interferon-activatable genes on murine chromosome 1. J Biol Chem 264: 17182–17189, 1989

    Google Scholar 

  • Cousar, J. B. and Briggs, R. C. Expression of human myeloid cell nuclear differentiation antigen (MNDA) in acute leukemias. Leuk Res 14: 915–920, 1990

    Google Scholar 

  • Dawson, M. J. and Trapani, J. A. The IFI 16 gene encodes a nuclear protein whose expression is induced by interferons in human myeloid leukemia cell lines. J Cell Biochem, in press

  • Engel, D. A., Samanta, H., Brawner, M. E., and Lengyel, P. Interferon action: transcriptional control of a gene specifying a 56,000-Da protein in Ehrlich Ascites Tumor Cells. Virology 142: 389–397, 1985

    Google Scholar 

  • Engel, D., Snoody, J., Toniato, E., and Lengyel, P. Interferons as gene activators: close linkage of two interferon-activatable murine genes. Virology 166: 24–29, 1988

    Google Scholar 

  • Gaczynski, M., Briggs, J. A., Wedrychowski, A., Olinski, R., Uskokovic, M., Lian, J. B., Stein, G. S., and Briggs, R. C. cisdiamminedichloroplatinum(II) cross-linking of the human myeloid cell nuclear differentiation antigen to DNA in HL-60 cells following 1,25-dihydroxyvitamin D3-induced monocyte differentiation. Cancer Res 50: 1183–1188, 1990

    Google Scholar 

  • Goldberger, A., Hnilica, L. S., Casey, S. B., and Briggs, R. C. Properties of a nuclear protein marker of human myeloid cell differentiation. J Biol Chem 261: 4726–4731, 1986

    Google Scholar 

  • Goldberger, A., Brewer, G., Hnilica, L. S., and Briggs, R. C. Non-histone protein antigen profiles of five leukemic cell lines reflect the extent of myeloid cell differentiation. Blood 63: 701–710, 1984

    Google Scholar 

  • Gunning, P., Pointe, P., Okayama, H., Engel, J., Blau, H., and Kedes, L. Isolation and characterization of full-length cDNA clones for human α-, β-, and λ-actin mRNAs: skeletal but not cytoplasmic actins have an amino terminal cysteine that is subsequently removed. Mol Cell Biol 3: 787–795, 1983

    Google Scholar 

  • Kingsmore, S. F., Watson, M. L., Howard, T. A., and Seldin, M. F. A. 6000 kb segment of chromosome 1 is conserved in human and mouse. EMBO J 8: 4073–4080, 1989

    Google Scholar 

  • Opdenakker, G., Snoddy, J., Choubey, D., Toniato, E., Pravtcheva, D. D., Seldin, M. F., Ruddle, M. F., and Lengyel, P. Interferons as gene activators: a cluster of six interferon-activatable genes is linked to the erythroid α-spectrin locus on murine chromasome 1. Virology 171: 568–578, 1989

    Google Scholar 

  • Samanta, H., Engel, D. A., Chao, H. M., Thakur, A., Garcia-Blanco, M. A., and Lengyel, P. Interferons as gene activators. Cloning of the 5′ terminus and the control segment of an interferon activated gene. J Biol Chem 261: 11849–11858, 1986

    Google Scholar 

  • Tannenbaum, C. S., Major, J., Ohmori, Y., and Hamilton, T. A. A lipopolysaccharide-inducible macrophage gene (D3) is a new member of an interferon-inducible gene cluster and is selectively expressed in mononuclear phagocytes. J Leukoc Biol 53: 563–568, 1993

    Google Scholar 

  • Trapani, J. A., Browne, K. A., Dawson, M. J., Ramsay, R. G., Eddy, R. L., Shows, T. B., White, P. C., and Dupont, B. A novel gene constitutively expressed in human lymphoid cells is inducible with interferon-λ in myeloid cells. Immunogenetics 36: 369–376, 1992

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Dawson, M.J., Trapani, J.A., Briggs, R.C. et al. The closely linked genes encoding the myeloid nuclear differentiation antigen (MNDA) and IFI16 exhibit contrasting haemopoietic expression. Immunogenetics 41, 40–43 (1995). https://doi.org/10.1007/BF00188431

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00188431

Keywords

Navigation