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Analysis of novel residues of class I involved in recognition by alloreactive T cells

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References

  • Bjorkman, P.J., Saper, M.A., Samraoui, B., Bennett, W.S., Strominger, J.L., and Wiley, D.C.: Structure of the human class I histocompatibility antigen, HLA-A2. Nature 329: 506–512, 1987a

    Google Scholar 

  • Bjorkman, P.J., Saper, M.A., Samraoui, B., Bennett, W.S., Strominger, J.L., and Wiley, D.C.: The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens. Nature 329: 512–518, 1987b

    Google Scholar 

  • Bluestone, J.A., Langlet, C., Geier, S.S., Nathenson, S.G., Foo, M., and Schmitt-Verhulst, A.-M.: Somatic cell variants express altered H-2Kb allodeterminants recognized by cytolytic T cell clones. J Immunol 137: 1244–1250, 1986

    Google Scholar 

  • Clayberger, C., Parham, P., Rothbard, J., Ludwig, D.S., Schoolnik, G.K., and Krensky, A.M.: HLA-A2 peptides can regulate cytolysis by human allogeneic T lymphocytes. Nature 330: 763–765, 1987

    Google Scholar 

  • Heath, W.R., Hurd, M., Carbone, F., and Sherman, L.A.: Peptide-dependent recognition of H-2Kb by alloreactive cytotoxic T lymphocytes. Nature 341: 749–752, 1989a

    Google Scholar 

  • Heath, W.R., Vitiello, A., and Sherman, L.A.: Mapping of epitopes recognized by alloreactive CTL using inhibition by MHC peptides. J Immunol 143: 1441–1446, 1989b

    Google Scholar 

  • McLaughlin-Taylor, E., Miyada, C.G., McMillan, M., and Wallace, R.B.: Direct demonstration of critical amino acid residues required for cytotoxic T-lymphocyte allorecognition of H-2 class I antigens. Proc Natl Acad Sci USA 85: 3085–3089, 1988

    Google Scholar 

  • Melief, C.J.M., De Waal, L.P., Van Der Meulen, M.Y., Melvold, R.W., and Kohn, H.I.: Fine specificity of alloimmune cytotoxic T lymphocytes directed against H-2K. A study with Kb mutants. J Exp Med 151: 993–1013, 1980

    Google Scholar 

  • Murray, R., Hutchison, C.A., III, and Frelinger, J.A.: Saturation mutagenesis of a major histocompatibility complex protein domain: identification of a single conserved amino acid important for allorecognition. Proc Natl Acad Sci USA 85: 3535–3539, 1988

    Google Scholar 

  • Murray, R., Katoh, K., Alexander, J., Muller, D., Pederson, K., and Frelinger, J.A.: Mutations in the α 1 domain of a class I gene define residues important for specific allorecognition. Cell Immunol, in press, 1990

  • Nathenson, S.A., Geliebter, J., Pfaffenbach, G.M., and Zeff, R.A.: Murine major histocompatibility complex class I mutants: molecular analysis and structure-function implications. Annu Rev Immunol 4: 471–502, 1986

    Google Scholar 

  • Parham, P., Clayberger, C., Zorn, S.L., Ludwig, D.S., Schoolnik, G.K., and Krensky, A.M.: Inhibition of alloreactive cytotoxic T lymphocytes by peptides from the α2 domain of HLA-A2. Nature 325:: 625–628, 1987

    Google Scholar 

  • Schneck, J., Maloy, W.L., Coligan, J.E., and Margulies, D.H.: Inhibition of an allospecific T cell hybridoma by soluble class I proteins and peptides: estimation of the affinity of a T cell receptor for MHC. Cell 56: 47–55, 1989

    Google Scholar 

  • Sheil, J.M., Bevan, M.J., and Sherman, L.A.: Immunoselection of structural H-2Kb variants: use of cloned cytolytic T cells to select for loss of a CTL-defined allodeterminant. Immunogenetics 23: 52–59, 1986

    Google Scholar 

  • Sherman, L.A.: Recognition of conformational determinants onH-2 by cytolytic T lymphocytes. Nature 297: 511–513, 1982

    Google Scholar 

  • Song, E.S., Linsk, R., Olson, C.A., McMillan, M., and Goodenow, R.S.: Allospecific cytotoxic T lymphocytes recognize an H-2 peptide in the context of a murine major histocompatibility complex class I molecule. Proc Natl Acad Sci USA 85: 1927–1931, 1988

    Google Scholar 

  • Vitiello, A. and Sherman, L.A.: Recognition of influenza-infected cells by cytolytic T lymphocyte clones: determinant selection by class I restriction elements. J Immunol 131: 1635–1640, 1983

    Google Scholar 

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Heath, W.R., Hurd, M.E., Murray, R. et al. Analysis of novel residues of class I involved in recognition by alloreactive T cells. Immunogenetics 32, 138–141 (1990). https://doi.org/10.1007/BF00210452

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