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The ultrastructure of pinealocytes in the pig

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Summary

Pinealocytes of female pigs were studied electron-microscopically and compared with those of other mammals. A prominent Golgi apparatus forming dense-cored vesicles was widely dispersed in the cytoplasm of the cell body. A very characteristic feature of the pig pinealocytes was the presence of membrane-bounded bodies showing wide variations in internal structure. Possible roles of the dense-cored vesicles and membrane-bounded bodies in secretory processes of pinealocytes are discussed.

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References

  • Arvy L (1971) Histoenzymology of the endocrine glands. Pergamon Press, Oxford

    Google Scholar 

  • Böcker W (1979) Funktionelle Pathomorphologie der menschlichen Schilddrüsentumoren. Gustav Fischer, Stuttgart

    Google Scholar 

  • Boer GJ, Jongkind JF (1974) Quantitative lysosomal enzyme activity changes in the neural lobe of the rat following water deprivation and lactation. J Neurochem 22:965–970

    Google Scholar 

  • Collin JP, Meiniel A (1972) L'organ pinéal du genre Lacerta (Reptile, Lacertilien): action d'enzymes protéolytiques sur les grains denses (500–3,400Å) des photorécepteurs rudimentaires. C R Soc Biol 166:2–3

    Google Scholar 

  • Collin JP, Juillard MT, Falcon J (1977) Localization of 5-hydroxytryptamine and protein(s) in the secretion granules of the rudimentary photoreceptor cells in the pineal of Lacerta. J Neurocytol 6:541–544

    Google Scholar 

  • Dogterom J, Snijdewindt FGM, Pévet P, Buijs RM (1979) On the presence of neuropeptides in the mammalian pineal gland and subcommissural organ. Progr Brain Res 52:465–470

    Google Scholar 

  • Dumm CLAG, Iturriza FC (1979) On the presence of conspicuous electron dense bodies in the pinealocytes of the pig. Cell Tissue Res 201:507–510

    Google Scholar 

  • Farquhar MG, Skutelsky EH, Hopkins CR (1975) Structure and function of the anterior pituitary and dispersed pituitary cells. In vitro studies. In: Tixier-Vidal A, Farquhar MG (eds) The anterior pituitary. Acad Press, New York, pp 83–135

    Google Scholar 

  • Ito T, Matsushima S (1968) Electron microscopic observations of the mouse pineal with particular emphasis on its secretory nature. Arch Histol Jpn 30:1–15

    Google Scholar 

  • Juillard MT (1979) The proteinaceous content and possible physiological significance of dense-cored vesicles in hamster and mouse pinealocytes. Ann Biol Anim Bioch Biophys 19:413–428

    Google Scholar 

  • Juillard MT, Collin JP (1978) The avian pineal organ: evidence for a proteinaceous component in the secretion granules of the rudimentary photoreceptor cells. An ultracytochemical and pharmacological study in the parakeet. Biol Cell 31:51–58

    Google Scholar 

  • Kappers J Ariëns (1969) The mammalian pineal organ. J Neuro Visc Rel Suppl 9:140–184

    Google Scholar 

  • Kappers J Ariëns (1971) The pineal gland: an introduction. In: Wolstenholme GEW, Knight J (eds) The pineal gland. Churchill Livingstone, Edinburgh, pp 3–22

    Google Scholar 

  • Kappers J Ariëns (1976) The mammalian pineal gland, a survey. Acta Neurochir. (Wien) 34:109–149

    Google Scholar 

  • Karasek M (1974) Ultrastructure of rat pineal gland in organ culture; influence of norepinephrine, dibutyryl cyclic adenosine 3′5′-monophosphate and adenohypophysis. Endokrinologie 64:106–114

    Google Scholar 

  • Karasek M (1980) Some functional aspects of the ultrastructure of rat pinealocytes. Endocrinol Exp (in press)

  • Karasek M, Pawlikowski M, Kappers J Ariëns, Stepień H (1976) Influence of castration followed by administration of LH-RH on the ultrastructure of rat pinealocytes. Cell Tissue Res. 167:325–339

    Google Scholar 

  • Kurosumi K, Fujita H (1975) Functional morphology of endocrine glands. Georg Thieme, Stuttgart

    Google Scholar 

  • Lin HS, Hwang BH, Tseng GY (1975) Fine structural changes in the hamster pineal gland after blinding and superior cervical ganglionectomy. Cell Tissue Res 158:285–299

    Google Scholar 

  • Meda P (1978) Lysosomes in normal pancreatic beta cells. Diabetologia 14:305–310

    Google Scholar 

  • Novikoff PM, Novikoff AB, Quintana N, Hauw JJ (1971) Golgi apparatus, GERL, and lysosomes of neurons in rat dorsal root ganglia, studied by thick sections and thin sections cytochemistry. J Cell Biol 50:859–886

    Google Scholar 

  • Ntunde BN, Hacker RR, Brown RG (1979) Aqueous porcine pineal extract: inhibition of ovulation induced with PMSG and HCG in immature mice. J Anim Sci 48:1422–1428

    Google Scholar 

  • Owman Ch (1964) New aspects of the mammalian pineal gland. Acta Physiol Scand 63: Suppl 240:1–40

    Google Scholar 

  • Owman Ch (1965) Localization of neuronal and parenchymal monoamines under normal and experimental conditions in the mammalian pineal gland. Progr Brain Res 10:425–454

    Google Scholar 

  • Pavel S (1965) Evidence for the presence of lysine vasotocin in the pig pineal gland. Endocrinology 77:812–817

    Google Scholar 

  • Pavel S (1978) Arginine vasotocin as a pineal hormone. J Neural Transm Suppl 13:135–155

    Google Scholar 

  • Petit A (1976) Contribution à l'étude de l'épiphyse des Reptiles: le complexe épiphysaire des Lacertiliens et l'épiphyse des ophidiens. Étude embryologique, structurale, ultrastructurale; analyse qualitative et quantitative de la sérotonine dans des conditions normales et expérimentales. Thèse, Strasbourg

  • Pévet P (1976) Correlation between pineal gland and sexual cycle. Thesis, Amsterdam

  • Pévet P (1977) On the presence of different populations of pinealocytes in the mammalian pineal gland. J Neural Transm 40:289–304

    Google Scholar 

  • Pévet P (1979) Secretory processes in the mammalian pinealocyte under natural and experimental conditions. Progr Brain Res 52:149–192

    Google Scholar 

  • Pévet P, Karasek M (1977) Are the pineal active compounds of mammals proteinaceous in nature? -An ultrastructural contribution. Acta Med Pol 18:351–353

    Google Scholar 

  • Pévet P, Kuyper MA (1978) The ultrastructure of pinealocytes in the golden mole (Amblysomus hottentotus) with special reference to the granular vesicles. Cell Tissue Res 191:39–56

    Google Scholar 

  • Picard D (1969) The neurosecretory cell of vertebrates. J Neuro Visc Rel Suppl 9:23–63

    Google Scholar 

  • Pilgrim Ch (1974) Histochemical differentiation of hypothalamic areas. Progr Brain Res 41:97–110

    Google Scholar 

  • Reinharz AC, Vallotton MB (1977) Presence of two neurophysins in the human pineal gland. Endocrinology 89:613–614

    Google Scholar 

  • Reinharz AC, Vallotton MB (1978) Evidence for the presence of neurohormone, neurophysins and peptidases in the pineal gland. J Neural Transm Suppl 13:393

    Google Scholar 

  • Reiter RJ (1974) Pineal-anterior pituitary gland relationship In: McCann SM (ed) MTP International Review of Science. Physiology Series One, Endocrine Physiology, Butterworths, London, Vol 5, pp 277–308

    Google Scholar 

  • Reiter RJ (1978) The pineal and reproduction. Basel, Karger (1978)

    Google Scholar 

  • Romijn HJ (1972) Structure and innervation of the pineal gland of the rabbit, Oryctolagus cuniculus (L), with some functional considerations. Thesis, Amsterdam

  • Romijn HJ, Mud MT, Wolters PS (1977) A pharmacological and autoradiographic study on the ultrastructural localization of indoleamine synthesis in the rabbit pineal gland. Cell Tissue Res 185:199–214

    Google Scholar 

  • Sheridan MN (1975) Pineal gland fine structure. Dense-cored vesicle. In: Brain — Endocrine Interaction. II. The Ventricular System. Karger, Basel, pp 303–327

    Google Scholar 

  • Sheridan MN, Reiter RJ (1968) The fine structure of the hamster pineal gland. Am J Anat 122:357–376

    Google Scholar 

  • Sheridan MN, Reiter RJ (1970) Observations in the pineal system in the hamster. II. Fine structure of the deep pineal. J Morphol 131:161–171

    Google Scholar 

  • Sheridan MN, Keppel JF (1971) The effect of p-chlorophenylalanine (PCPA) and 6-hydroxydopamine (6-HD) on ultrastructural features of hamster pineal parenchyma. Anat Rec 169:427

    Google Scholar 

  • Sheridan MN, Sladek Jr, JR (1975) Histofluorescence and ultrastructural analysis of hamster and monkey pineal. Cell Tissue Res 164:145–152

    Google Scholar 

  • Smith RE, Farquhar MG (1966) Lysosome function in the regulation of the secretory process in cells of the anterior pituitary gland. J Cell Biol 31:319–347

    Google Scholar 

  • Vivien-Roels B (1976) L'épiphyse des Chéloniens. Étude embryologique, structurale, ultrastructurale; analyse qualitative et quantitative de la serotonine dans des conditions normales et experimentales. Thése, Strasbourg

  • Wartenberg H (1968) The mammalian pineal organ: electron microscopic studies of the fine structure of pinealocytes, glial cells and of the perivascular compartment. Z Zellforsch 86:74–97

    Google Scholar 

  • Wollman SH (1965) Heterogeneity of the thyroid gland. In: Cassano C, Andreoli M (eds) Current topics in thyroid research. Academic Press, New York, pp 1–18

    Google Scholar 

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Authors and Affiliations

  1. Laboratory of Electron Microscopy, Department of Pathological Anatomy, Institute of Pathology, Medical Academy, Sterlinga 5, 91-425, Lódź, Poland

    M. Karasek (Assoc. Prof.)

  2. Department of Histology, Institute of Fundamental Veterinary Sciences, Academy of Agriculture and Technology, Olsztyn, Poland

    Z. Wyrzykowski

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  1. M. Karasek
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  2. Z. Wyrzykowski
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Karasek, M., Wyrzykowski, Z. The ultrastructure of pinealocytes in the pig. Cell Tissue Res. 211, 151–161 (1980). https://doi.org/10.1007/BF00233730

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