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Production of citric acid by Aspergillus niger immobilized in polyacrylamide gels

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Summary

Living Aspergillus niger cells were entrapped in polyacrylamide gels and employed in both replacement batch and continuous column bioreactors to produce citric acid from sucrose. With the replacement batch bioreactor, increase of citric acid was observed under conditions of higher aeration and of wider surface of immobilized cells. With the continuous bioreactor, the maximum citric acid yield was 39.1 mg/h per 40 g gels. The biocatalyst activity or half-life was 105 days.

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Authors and Affiliations

  1. Department of Agricultural Chemistry, Gifu University, 501-11, Gifu, Japan

    Hiroyuki Horitsu, Shigetoshi Adachi, Yasushi Takahashi & Keiichi Kawai

  2. Iwata Chemical Industry Co., Ltd., 438, Iwata, Shizuoka, Japan

    Yoshio Kawano

Authors
  1. Hiroyuki Horitsu
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  2. Shigetoshi Adachi
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  3. Yasushi Takahashi
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  4. Keiichi Kawai
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  5. Yoshio Kawano
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Horitsu, H., Adachi, S., Takahashi, Y. et al. Production of citric acid by Aspergillus niger immobilized in polyacrylamide gels. Appl Microbiol Biotechnol 22, 8–12 (1985). https://doi.org/10.1007/BF00252149

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  • DOI: https://doi.org/10.1007/BF00252149

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