Summary
Two antifungal antibiotics, named PA-5 and PA-7 were produced by an actinomycete strain, characterized and identified as Streptoverticillium sp 43/16. These antibiotics were extracted from mycelial cake with methanol and purified using different organic solvents and LH-20 Sephadex column chromatography. PA-5 and PA-7 were characterized as, a pentaene and a heptaene macrolide antibiotic, respectively. These antibiotics exhibit strong antifungal activity against pathogen yeasts and molds.
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Soliveri, J., Arias, ME. & Laborda, F. PA-5 and PA-7, pentaene and heptaene macrolide antibiotics produced by a new isolate of Streptoverticillium from Spanish soil. Appl Microbiol Biotechnol 25, 366–371 (1987). https://doi.org/10.1007/BF00252549
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DOI: https://doi.org/10.1007/BF00252549