Skip to main content
SpringerLink
Log in

Indole alkaloids from cell suspension cultures of Rauwolfia serpentina benth

  • Published:
Plant Cell Reports Aims and scope Submit manuscript

Abstract

Twelve indole alkaloids belonging to the Ajmaline-, Sarpagine-, Yohimbine-, and Heteroyohimbine-type have been isolated and identified from cell suspension cultures of Rauwolfia serpentina. Ten of the alkaloids were found for the first time in cultured R. serpentina cells. The yield of the main alkaloid vomilenine was 51 times more than that of differentiated plants. Crude enzymes isolated from this cell suspension culture completely metabolize the biogenetic precursor strictosidine under formation of several alkaloidal compounds.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Akinloye BA and Court WE (1980) Phytochemistry 19: 2741–2745, ibid. 19: 307–311, 19: 1833–36

    Google Scholar 

  • Bite IP, Pongrácz-Sterk L, Diszler E (1963) Magyar Kémiai Folyoirat 63: 84–87

    Google Scholar 

  • Cordell GA (1974) Lloydia 37: 219–289

    Google Scholar 

  • Hofmann A, Frey AJ (1957) Helv.Chim.Acta 40: 1866–1874

    Google Scholar 

  • Meisel H, Döpke W (1971) Tetrahedron Letters 1291–1293

  • Ohta S, Yatazawa M (1979) Agric.Biol.Chem. 43: 2297–303

    Google Scholar 

  • Stöckigt J, Soll HJ (1980) Planta medica 40: 22–30

    Google Scholar 

  • Taylor WI, Frey AJ, Hofmann A (1962) Helv.Chim.Acta 45: 611–614

    Google Scholar 

  • Tukhatasinov MKh, Kiryalov NP, Butenko RG, Grushivitskii IV, Grurevich IYa, Nikitina IK (1977) Khim Priv.Soedin. 1: 122–3 [C.A. (1977) 87: 65339h]

    Google Scholar 

  • Vollosovich AG, Nikolaeva LA, Zharko TR (1972) Rast. Resur. 8: 331–8 [C.A. (1972) 77: 111529p]

    Google Scholar 

  • Vollosovich AG, Tsarenko NYa (1968) Tr.Leningrad Khim-Farm Inst. 26: 214–17 [C.A. (1970) 73: 63237k]

    Google Scholar 

  • Zenk MH (1980) J.Nat.Products 43: 438–451

    Google Scholar 

  • Zenk MH, El-Shagi H, Arens H, Stöckigt J, Weiler EW, Deus B (1977) In: Barz W, Reinhard E, Zenk MH (eds.) Plant Tissue Culture and Its Biotechnological Application, Springer, Berlin Heidelberg New York, pp 27–43

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Lehrstuhl Pharmazeutische Biologie, Ludwig-Maximilians-Universität, D-8000, München, Federal Republic of Germany

    Joachim Stöckigt, Artur Pfitzner & Joachim Firl

  2. Organisch-Chemisches Institut der TU München, D-8046, Garching, Federal Republic of Germany

    Joachim Firl

Authors
  1. Joachim Stöckigt
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Artur Pfitzner
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Joachim Firl
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Stöckigt, J., Pfitzner, A. & Firl, J. Indole alkaloids from cell suspension cultures of Rauwolfia serpentina benth. Plant Cell Reports 1, 36–39 (1981). https://doi.org/10.1007/BF00267656

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00267656

Keywords

Search

Navigation