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A Markov chain model for human granulocyte movement

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Summary

A continuous-time Markov chain is used to model the two dimensional movement of human granulocytes. The states of the Markov chain are the angles at which the cells move relative to a fixed axis. The method is used to determine the most probable direction of cell movement and to measure quantitatively any chemotactic or aggregative effect. The theory is applicable to any type of cell whose motion follows a zig-zag pattern.

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References

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Authors and Affiliations

  1. Department of Mathematics, Sir George Williams Campus, Concordia University, Montreal, Canada

    A. Boyarsky

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  1. A. Boyarsky
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Additional information

This research was supported by a grant from the National Research Council of Canada. Grant No. A9072.

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Boyarsky, A. A Markov chain model for human granulocyte movement. J. Math. Biology 2, 69–78 (1975). https://doi.org/10.1007/BF00276017

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  • DOI: https://doi.org/10.1007/BF00276017

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