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Regional chromosomal assignment of the human mineralocorticoid receptor gene to 4q31.1

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Summary

The gene for human mineralocorticoid receptor (hMR), previously mapped to chromosome 4, has been further localized to 4q31.1 by in situ hybridization using a biotinylated 3.75kb human cDNA clone encoding the primary amino acid sequence of hMR as a probe. Preliminary comparative mapping studies in orangutan (Pongo pygmaeus) suggest localization of the probe to the long arm of chromosome 3.

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Authors and Affiliations

  1. Duncan Guthrie Institute of Medical Genetics, Yorkhill, G3 8SJ, Glasgow, UK

    Norma Morrison, Elizabeth Boyd & J. Michael Connor

  2. MRC Blood Pressure Unit, Western Infirmary, G11 6NT, Glasgow, UK

    Stephen B. Harrap

  3. Gene Expression Laboratory, The Salk Institute for Biological Studies, P.O.Box 85800, 92138, San Diego, CA, USA

    Jeffrey L. Arriza

Authors
  1. Norma Morrison
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  2. Stephen B. Harrap
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  3. Jeffrey L. Arriza
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  4. Elizabeth Boyd
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  5. J. Michael Connor
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Morrison, N., Harrap, S.B., Arriza, J.L. et al. Regional chromosomal assignment of the human mineralocorticoid receptor gene to 4q31.1. Hum Genet 85, 130–132 (1990). https://doi.org/10.1007/BF00276340

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  • DOI: https://doi.org/10.1007/BF00276340

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