Summary
4 cases of “? chromosome abnormality”, referred to this department in the past 3 months, have shown an aberrant complement of chromosome 18. Chromosome 18 has been identified using a modification of Seabright's (1971) method of banding human chromosomes.
Zusammenfassung
Vier Fälle mit fraglicher Chromosomen-Anomalie, die während der vergangenen 3 Monate an diese Abteilung überwiesen wurden, zeigten ein abnormes Chromosom Nr. 18. Chromosom 18 wurde mit Hilfe einer Modifikation von Seabright (1971) für die Darstellung von Bandenmustern identifiziert.
References
Carr, D. H.: Chromosome studies in spontaneous abortions. Obstet. and Gynec. 26, 308 (1965).
Levenson, J. E., Crandall, B. F., Sparkes, R. S.: Partial deletion syndromes of chromosome 18. Ann. Opthal. 3, 756–760 (1971).
Seabright, M.: A rapid banding technique for human chromosomes. Lancet 1971 II, 971–972.
Sumner, A. T., Evans, H. J., Buckland, R. A.: New technique for distinguishing between human chromosomes. Nature (Lond.) New Biol. 232, 31–32 (1971).
Taylor, A. I.: Autosomal trisomy syndromes: A detailed study of 27 cases of Edwards' syndrome and 27 cases of Patau's syndrome. J. med. Genet. 5, 227–252 (1968).
Weber, F. M., Sparkes, R. S.: Trisomy E (18) syndrome, clinical spectrum in 12 new cases, including autoradiography in 4. J. med. Genet. 7, 363–366 (1970).
Author information
Authors and Affiliations
Additional information
Supported in part by United Sheffield Hospitals Research Grant Code 309.
Rights and permissions
About this article
Cite this article
Curtis, D.J. Chromosome number 18. Hum Genet 18, 273–277 (1973). https://doi.org/10.1007/BF00290608
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00290608