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Sister chromatid exchanges in leukocytes of patients with cancer of cervix uteri

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Summary

The frequency of sister chromatid exchange (SCE) was investigated in 13 women with cervical cancer together with 11 control women. The SCE frequencies were found to be 10.05±2.35 and 6.95±1.53 in cancer cases and controls, respectively. The SCE values of cancer cases deviate significantly from that of controls. The SCE in chromosome groups E, F, and G was found to be more in comparison to controls (P<0.001). This preliminary study indicates the possibility of using SCE as a preclinical marker.

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Authors and Affiliations

  1. Cytology Research Centre (Indian Council of Medical Research), Maulana Azad Medical College Campus, 1100 02, New Delhi, India

    A. B. Mitra, V. V. V. S. Murty & U. K. Luthra

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  1. A. B. Mitra
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  2. V. V. V. S. Murty
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  3. U. K. Luthra
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Mitra, A.B., Murty, V.V.V.S. & Luthra, U.K. Sister chromatid exchanges in leukocytes of patients with cancer of cervix uteri. Hum Genet 60, 214–215 (1982). https://doi.org/10.1007/BF00303005

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  • DOI: https://doi.org/10.1007/BF00303005

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