Summary
Fluorescent histochemical studies have been made on the mucosa of the gut of a mammal (guinea-pig) and of some lower vertebrates (trout, eel, toad and lizard). Adrenergic nerves in the mucosa generally occur in perivascular plexuses. There appears to be no adrenergic innervation of the muscularis mucosae.
Yellow fluorescent enterochromaffin cells were observed in the mucosal epithelium of all species, including fish. Autofluorescent structures in the mucosa of these animals have also been described and were particularly prominent in the large intestines of teleost fish.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Åberg, G., and O. Eränkö: Localization of noradrenaline and acetylcholinesterase in the taenia of the guinea-pig caecum. Acta physiol. scand. 69, 383–384 (1967).
Baumgarten, H. G.: Vorkommen und Verteilung adrenerger Nervenfasern im Darm der Schleie (Tinca vulgaris Cuv.). Z. Zellforsch. 76, 248–259 (1967a).
—: Über die Verteilung von Catecholaminen im Darm des Menschen. Z. Zellforsch. 83, 133–146 (1967b).
Bennett, M. R., and D. C. Rogers: A study of the innervation of the taenia coli. J. Cell Biol. 33, 573–596 (1967).
Burnstock, G.: The innervation of the gut of the brown trout (Salmo trutta). Quart. J. micr. Sci. 100, 199–220 (1959).
Campbell, G., and G. Burnstock: Comparative physiology of gastrointestinal motility. In: Handbook of physiology. Alimentary canal. American Physiological Society, 2213–2266 (1968).
Enemar, A., B. Falck, and R. Håkanson: Observations on the appearance of norepinephrine in the sympathetic nervous system of the chick embryo. Devl. Biol. 11, 268–283 (1965).
Eränkö, O.: Distribution of fluorescing islets, adrenaline and noradrenaline in the adrenal medulla of the hamster. Acta endocr. (Kbh.) 18, 174–179 (1955).
Erspamer, V.: Pharmacology of indolealkylamines. Pharmacol. Rev. 6, 425–487 (1954).
Fänge, R.: Pharmacology of poikilothermic vertebrates and invertebrates. Pharmacol. Rev. 14, 281–316 (1962).
Fahlén, G., B. Falck, and E. Rosengren: Monoamines in the swimbladder of Gadus callarias and Salmo irideus. Acta physiol. scand. 64, 119–126 (1965).
Falck, B.: Observations on the possibilities of the cellular localization of monoamines by a fluorescence method. Acta physiol. scand. 56, Suppl. 197 (1962).
Gabella, G., e M. Costa: Le fibre adrenergiche nel canale alimentare. G. Accad. Med. Torino 130, 1–12 (1967).
—: Adrenergic fibres in the mucous membrane of guinea-pig alimentary tract. Experientia (Basel) 24, 706–707 (1968).
Hill, C. J.: A contribution to our knowledge of the enteric plexuses. Phil. Trans. B 215, 355–388 (1927).
Hollands, B. C. S., and S. Vanov: Localization of catechol amines in visceral organs and ganglia of the rat, guinea-pig and rabbit. Brit. J. Pharmacol. 25, 307–316 (1965).
Jacobowitz, D.: Histochemical studies of the autonomic innervation of the gut. J. Pharmacol. exp. Ther. 149, 358–364 (1965).
Leont'eva, G. R.: Distribution of catechol amines in blood vessel walls of Cyclostomata, fishes, amphibia, and reptiles. Z. Evolyutsionnoi Biokhim. i Fiziol. 1, 31–36 (1966a). Abstract in Chem. Abstr. 65, 1091G (1966).
—: Distribution of catechol amines in the walls of blood vessels in warm-blooded animals. Arkh. Anat. Gistol. i Embriol. 50, 36–41 (1966b). Abstract in Chem. Abstr. 65, 2716D (1966).
McLean, J. R., and G. Burnstock: Histochemical localization of catecholamines in the urinary bladder of the toad (Bufo marinus). J. Histochem. Cytochem. 14, 538–548 (1966).
Norberg, K.-A.: Adrenergic innervation of the intestinal wall studied by fluorescence microscopy. Int. J. Neuropharmacol. 3, 379–382 (1964).
—: Transmitter histochemistry of the sympathetic adrenergic nervous system. Brain Res. 5, 125–170 (1967).
—, and F. Sjöqvist: New possibilities for adrenergic modulation of ganglionic transmission. Pharmacol. Rev. 18, 743–751 (1966).
Penttilä, A.: 5-Hydroxytryptamine in the enterochromaffin cells of the guinea pig alimentary tract. Histochemie 11, 185–194 (1967).
Read, J. B., and G. Burnstock: Comparative histochemical studies of adrenergic nerves in the enteric plexuses of vertebrate large intestine. Comp. Biochem. Physiol., 27, 505–517 (1968).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Read, J.B., Burnstock, G. Fluorescent histochemical studies on the mucosa of the vertebrate gastrointestinal tract. Histochemie 16, 324–332 (1968). https://doi.org/10.1007/BF00306355
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00306355