Summary
Epileptic seizures due to thrombotic cerebral infarction were studied in 118 patients. The occurrence of seizures had a bimodal distribution with one peak period within 2 weeks and another peak period from 6 to 12 months after stroke. Four patients had seizures preceding stroke, while 23 patients without a history of previous stroke had “silent infarct” on the CT scan. Fifteen patients (13%) had status epilepticus. Simple partial seizures occurred in 56% of patients, complex partial seizures in 24% and generalized tonic-clonic seizures in 4%. Epilepsy developed in 35% of patients with early seizures and in 90% of patients with late seizures.
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References
Annergers JF, Gralow JD, Groover RV, Laws ER, Elveback LR, Kurland T (1980) Seizures after head trauma: a population study. Neurology 30:683–689
Aring CD, Merritt HH (1935) Differential diagnosis between cerebral hemorrhage and cerebral thrombosis; a clinical and pathologic study of 245 cases. Arch Intern Med 56:435–456
Avrahami E, Drory VE, Raby MJ, Cohn DF (1988) Generalized epileptic seizures as the presenting symptom of lacunar infarction in the brain. J Neurol 235:472–474
Bogousslavsky J, Regli F (1986) Unilateral watershed cerebral infarcts. Neurology 36:373–377
Celesia GG (1976) Modern concepts of status epilepticus. JAMA 235:1571–1574
Cocito L, Favale E, Reni L (1982) Epileptic seizures in cerebral arterial occulsive disease. Stroke 13:189–195
Commission on classification and terminology of the International League Against Epilepsy (1981) Proposal for revised clinical and electroencephalographic classification of epileptic seizures. Epilepsia 22:489–501
De la Sayette V, Cosgrove R, Melanson D, Ethier R (1987) CT findings in late-onset epilepsy. Can J Neurol Sci 14:286–289
Dodge PR, Richardson EP JR, Victor M (1954) Recurrent convulsive seizures as a sequel to cerebral infarction: a clinical and pathological study. Brain 77:610–638
Easton JD, Sherman DG (1980) Management of cerebral embolism of cardiac origin. Stroke 11:433–442
Fentz V (1971) Epileptic seizures in patients with cerebrovascular accidents (in Swedish). Nord Med 86:1023–1025
Fisher CM (1982) Lacunar strokes and infarcts: a review. Neurology 32:871–876
Lesser RP, Lüders H, Dinner DS, Morris HH (1985) Epileptic seizures due to thrombotic and embolic cerebrovascular disease in older patients. Epilepsia 26:622–630
Louis S, McDowell F (1967) Epileptic seizures in nonembolic cerebral infarction. Arch Neurol 17:414–418
Lühdorf K, Jensen LK, Plesner AM (1986) Etiology of seizures in the elderly. Epilepsia 27:458–463
Meyer JS, Charney JZ, Rivera VM, Mathew NT (1971) Cerebral embolization: prospective clinical analysis of 42 cases. Stroke 2:541–554
Miller VT (1983) Lacunar stroke: a reassessment. Arch Neurol 40:129–134
Mohr JP, Caplan LR, Melski JW, Goldstein RJ, Duncan GW, Kistler JP, Pessin MS, Bleich HL (1978) The Harvard cooperative stroke registry: a prospective registry. Neurology 28:754–762
Nadeau SE (1986) Stroke due to cardiogenic embolism. Semin Neurol 6:277–284
Okada Y, Yamaguchi T, Minematsu K, Miyashita T, Sawada T, Sadoshima S, Fujishima M, Omae T (1989) Hemorrhagic transformation in cerebral embolism. Stroke 20:598–603
Oxbury JM, Whitty CWM (1971) Causes and consequences of status epilepticus in adults. Brain 94:733–744
Pirttimaki R, Narva EV, Ruikka I (1977) Epilepsy as a sequel to cerebrovascular accident. Scand J Soc Med 14:134–140
Ramirez-Lassepas M, Cipolle RJ, Bjork RJ, Kowitz J, Snyder BD, Weber JC, Stein SD (1987) Can embolic stroke be diagnosed on the basis of neurologic clinical criteria? Arch Neurol 44:87–89
Richardson EP, Dodge PR (1954) Epilepsy in cerebral vascular disease. A study of the incidence and nature of seizures in 104 consecutive autopsy-proven cases of cerebral infarction and hemorrhage. Epilepsia 3:49–65
Roberts RC, Shorvon SD, Cox TCS, Gilliatt RW (1988) Clinically unsuspected cerebral infarction revealed by computed tomography scanning in late onset epilepsy. Epilepsia 29:190–194
Schold C, Yarnell PR, Earnest MP (1977) Origin of seizures in the elderly patients. JAMA 238:1177–1178
Shinton RA, Gill JS, Zezulka AV, Beevers DG (1987) The frequency of epilepsy preceding stroke. Case-control study in 230 patients. Lancet I:11–13
Shorvon SD, Gilliatt RW, Cox CS, Yu YL (1984) Evidence of vascular disease from CT scanning in late onset epilepsy. J Neurol Neurosurg Psychiatry 47:225–230
Sung C-Y, Chu N-S (1990) Seizures in elderly people: aetiology and seizure type. Age Ageing (in press)
Sung C-Y, Chu N-S (1989) Epileptic seizures in intracerebral hemorrhage. J Neurol Neurosurg Psychiatry 52:1273–1276
Walker AE, Jablon S (1961) A follow-up study of head wounds in World War II. VA Medical Monograph. US Government Printing Office, Washington, DC
Wodarz R (1980) Watershed infarctions and computed tomoraphy. A topographical study in cases with stenosis or occlusion of the carotid artery. Neuroradiology 19:245–248
Zülch KJ (1961) Über die Entstehung und Lokalisation der Hirninfarkte. Neurochirurgia (Stuttg) 21:158–178
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Sung, CY., Chu, NS. Epileptic seizures in thrombotic stroke. J Neurol 237, 166–170 (1990). https://doi.org/10.1007/BF00314589
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DOI: https://doi.org/10.1007/BF00314589