Skip to main content
Log in

The quantitative estimation of toluene skin absorption in man

  • Published:
Internationales Archiv für Gewerbepathologie und Gewerbehygiene Aims and scope Submit manuscript

Summary

The absorption of toluene through the skin of the hand and the forearm in men was investigated experimentally. Both the absorption of liquid toluene and the absorption from aqueous solutions were studied using the direct method. It was stated that under the experimental conditions the rate of absorption of liquid toluene was 14–23 mg/cm2/h.

In mean concentrations of 180–600 mg/1 the rate of absorption of toluene from aqueous solutions was 160-600 μg/cm2/h and increased according to the increase of toluene concentration.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Baranowska, B.: Report on II Symposium of Industrial Toxicology Socialistic Countries Łódź 8, 12 (1965).

    Google Scholar 

  • Dutkiewicz, T., I. Kęsy-Dąbrowska, and I. Piotrowski: The determination of toxic compounds in the air, 2 ed., p. 185. Warszawa: P. Z. W. L. 1965.

    Google Scholar 

  • Dutkiewicz, T., and H. Tyras: Report on II Symposium of Industrial Toxicology Socialistic Countries Łódź 8, 12 (1965).

    Google Scholar 

  • Dutkiewicz, T., and H. Tyras: A study of the skin absorption of ethylbenzene in man. Brit. J. industr. Med. 24, 330–332 (1967).

    Google Scholar 

  • Grabowicz, W.: The modification of colorimetric method of toluene determination and its nitro derivatives in air. Med. Pracy 6, 297–301 (1955).

    Google Scholar 

  • Gerarde, H. W.: Toxicology and biochemistry of aromatic hydrocarbons, p. 142. Amsterdam-London-New York: Elsevier 1960.

    Google Scholar 

  • Guertin, G. L., and H. W. Gerarde: Toxicological studies on hydrocarbons. IV. A method for quantitative determination of benzene and certain alkylbenzenes in blood. A.M.A. Arch. Ind. Health 20, 262–290 (1959).

    Google Scholar 

  • Hanke, J., T. Dutkiewicz, and I. Piotrowski: The absorption of benzene through the skin in men. Med. Pracy 12, 413–426 (1961).

    Google Scholar 

  • Piotrowski, J.: Quantitative evaluation of exposure to toluene in men. Med. Pracy 18, 213–223 (1967).

    Google Scholar 

  • Valette, G., and R. Cavier: Percutaneous absorption and chemical constitution. Hydrocarbons, alcohols and esters. Arch. int. Pharmacodyn. 97, 232–235 (1954).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Dutkiewicz, T., Tyras, H. The quantitative estimation of toluene skin absorption in man. Int. Archv fü Gewerbepathologie und Gewerbehygiene 24, 253–257 (1968). https://doi.org/10.1007/BF00345921

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00345921

Keywords

Navigation