Abstract
This paper is the first one presenting an application of the control law based on the ratio of measured and optimal values for a real fermentation pilot plant operated in continuous mode. A controller of this type takes into account the process variables and may be designed by using classical linear methods. A simple algorithm is applied for a real CSTR to control the substrate concentration. The results obtained confirm that this approach offers the possibility to combine simplicity and effectiveness in bioprocess control.
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Vigié, P., Dahhou, B., Queinnec, I. et al. Control of substrate concentration in a continuous bioprocess. Bioprocess Engineering 6, 259–263 (1991). https://doi.org/10.1007/BF00369555
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DOI: https://doi.org/10.1007/BF00369555