Summary
Tenascin, a recently discovered extracellular matrix protein, was demonstrated in perifollicular connective tissue of normal human scalp using immunohistochemistry. Its localization was different from other well-known extracellular matrix components, like fibronectin, laminin and heparan sulphate proteoglycan. A comparison between alopecia areata and normal scalps did not reveal major qualitative differences, except for an increased expression near heavily infiltrated follicles.
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van Baar, H.M.J., Perret, C.M., van Vlijmen-Willems, I.M.J.J. et al. Expression of tenascin in perifollicular connective tissue: comparison of normal scalp and alopecia areata. Arch Dermatol Res 283, 86–90 (1991). https://doi.org/10.1007/BF00371614
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DOI: https://doi.org/10.1007/BF00371614