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Junctions between the cells of the trabecular meshwork

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Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie Aims and scope Submit manuscript

Summary

In an electron-microscopic study of cell-to-cell attachments in the trabecular meshwork of three primate species and the rabbit, two types of junctions were identified. These junctions were common to all four species. One was classified as a macula adhaerens while the other, after uranyl acetate “en bloc” treatment of the tissue, was thought to be a macular gap junction. These junctions were common to all regions of apposition in the meshwork although their incidence in isolated sections was low; their possible role as an adhesive mechanism was discussed.

Zusammenfassung

In einer elektronenmikroskopischen Studie der Intercellularverbindungen des Trabekelwerkes bei drei Primatenarten und beim Kaninchen wurden zwei Typen von Verbindungen identifiziert. Diese fanden sich gleichermaßen bei allen vier Species. Die eine Intercellularverbindung wurde als Macula adhaerens klassifiziert, während die andere nach en-bloc-Behandlung mit Uranylacetat für eine maculäre Gap junction gehalten wurde. Obwohl das Vorkommen dieser Verbindungen in Einzelschnitten relativ selten war, fanden sie sich doch überall dort, wo im Trabekelwerk Zellen aneinander stießen. Ihre mögliche Rolle im Sinne eines Adhäsionsmechanismus wird diskutiert.

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Authors and Affiliations

  1. Tennent Institute of Ophthalmology, The University, Glasgow

    I. Grierson & W. R. Lee

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  1. I. Grierson
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  2. W. R. Lee
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Grierson, I., Lee, W.R. Junctions between the cells of the trabecular meshwork. Albrecht von Graefes Arch. Klin. Ophthalmol. 192, 89–104 (1974). https://doi.org/10.1007/BF00410696

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  • DOI: https://doi.org/10.1007/BF00410696

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