Summary
cur-1, a mutation found in many strains of the Y10 line of Escherichia coli K-12, but not previously described, maps at 27 min, close to galU. cur-1 causes mucoidity or uracil requirement at 29°C depending on the genetic background. These phenotypes are suppressed by amber codon suppressors.
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References
Bachmann BJ (1972) Pedigrees of some mutant strains of E. coli K-12. Bacteriol Rev 36:525–557
Bush JW, Markovitz A (1973) The genetic basis for mucoidity and radiation sensitivity in capR (lon) mutants of E. coli K-12. Genetics 74:215–225
Diderichsen B (1980) flu, a metastable gene controlling surface properties of E. coli. J Bacteriol 141:858–867
Diderichsen B, Desmarez L (1980) Variations in phenotype of relB mutants of E. coli and the effect of pus and sup mutations. Mol Gen Genet 180:429–437
Donch J, Greenberg J (1968) Ultraviolet sensitivity of E. coli B. J Bacteriol 95:1555–1559
Franklin NC (1969) Mutation in galU gene of E. coli blocks phage Pl infection. Virology 38:189–191
Hua SS, Markovitz A (1972) Multiple regulator gene control of the galactose operon in E. coli K-12. J Bacteriol 110:1089–1099
Lieberman M, Markovitz A (1970) Depression of guanosine diphosphatemannose pyrophosphorylase by mutations in two different regulator genes involved in capsular polysaccharide synthesis in E. coli K-12. J Bacteriol 101:965–972
Markovitz A (1964) Regulatory mechanisms for synthesis of capsular polysaccharide in mucoid mutants of E. coli K-12. Proc Natl Acad Sci USA 51:239–246
Markovitz A, Sydikis RJ, Lieberman M (1967) Genetic and biochemical studies on mannose-negative mutants that are deficient in phosphomannose-isomerase in E. coli K-12. J Bacteriol 94:1492–1496
Womack JE, O'Donovan GA (1978) Orotic acid excretion in some wild-type strains of E. coli K-12. J Bacteriol 136:825–828
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Communicated by A. Böck
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Diderichsen, B. cur-1, a mutation affecting the phenotype of sup + strains of Escherichia coli . Molec. Gen. Genet. 180, 425–428 (1980). https://doi.org/10.1007/BF00425858
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DOI: https://doi.org/10.1007/BF00425858