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An electron microscope study of the Auerbach's plexus and determination of substance P of the colon in Hirschsprung's disease

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Summary

The AA present a study of 3 cases of Hirschsprung's disease performed under electron microscopy and whose data seen to suggest that substance P, which is always found in larger amounts in the ganglionic portion of the colon (than in the aganglionic one), may be related with the granular vesicles of Auerbach's plexus.

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References

  • Baumgarten, H. G., Holstein, A. F., Stelzner, F.: Nervous elements in the human colon of Hirschsprung's disease. Virchows Arch. Abt. A. 358, 113–136 (1973)

    Google Scholar 

  • Ehrenpreis, T., Pernow, B.: On the occurrence of substance P in the rectosigmoide in Hirschsprung's disease. Acta physiol. scand. 27, 380–388 (1953)

    Google Scholar 

  • Farrel, K.: Histochemical and ultrastructural observations on human aganglionic megacolon. J. Anat. (Lond.) 106, 206 (1970)

    Google Scholar 

  • Gadun, J. H.: In: Polypeptides, vol. 4, Symposium Publications Division, London: Pergamon Press of Lord 1959

    Google Scholar 

  • Hial, W., Ribeiro Diniz, C., Pittella, J. E. H., Tafuri, W. L.: Quantitative study of P substance in the megaesophagus and megacolon of human trypanosoma Cruzi infections. J. trop. Med. Hyg. 76, 175–179 (1973)

    Google Scholar 

  • Howards, E. R., Garret, J. R.: Histochemistry and electron microscopy of rectum and colon in Hirschsprung's disease. Proc. roy. Soc. Med. 63, 1264–1266 (1970)

    Google Scholar 

  • Nozelof, C., Guy-Grand, D. U., Thomine, E.: Les mégacolons avec hyperplasie des plexus myentériques. Presse méd. 78, 1501–1506 (1970)

    Google Scholar 

  • Pellegrino de Iraldi, A.: Significado das vesículas granuladas no sistema nervoso central e periférico. Simpósio “Estruturas Sub-Celulares”. IX Congresso Associação Latino-Americana de Ciências Fisiológicas. Belo Horizonte, julho (1969)

  • Tafuri, W. L.: Ultrastructure of vesicular component in the intramural nervous system of the guinea-pig's intestine. Z. Naturforsch. 19b, 622–625 (1964)

    Google Scholar 

  • Tafuri, Maria, T. A., Lopes, E. R.: Lesões do plexo mientérico do esôfago, do jejuno e do colo de chagásicos crônicos. Estudo ao microscópic eletrônic. Rev. Inst. Med. trop. S. Paulo 13, 76–91 (1971)

    Google Scholar 

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Tafuri, W.L., Maria, T.A., Pittella, J.E.H. et al. An electron microscope study of the Auerbach's plexus and determination of substance P of the colon in Hirschsprung's disease. Virchows Arch. A Path. Anat. and Histol. 362, 41–50 (1974). https://doi.org/10.1007/BF00433773

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