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Reaction of 5-substituted 4,6-dichloro-2-aminopyrimidines with oxalyl chloride

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The reaction of 5-substituted 4,6-dichloro-2-aminopyrimidines with oxalyl chloride gives 2-isocyanatopyrimidines, the structures of which were proved by chemical means and the IR, PMR, and 35Cl nuclear quadrupole resonance spectra. The intermediate pyrimidinyloxamic acid chlorides were not isolated; this is evidently explained by the low basicities of 2-amino-pyrimidines.

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Authors and Affiliations

  1. Institute of Organic Chemistry, Academy of Sciences of the Ukrainian SSR, 252660, Kiev

    I. V. Boldyrev, I. F. Vladimirtsev, E. A. Romanenko, N. G. Korzhenevskaya, E. V. Titov & V. M. Cherkasov

  2. Institute of Physical Organic Chemistry and Coal Chemistry, Academy of Sciences of the Ukrainian SSR, 340048, Donetsk

    I. V. Boldyrev, I. F. Vladimirtsev, E. A. Romanenko, N. G. Korzhenevskaya, E. V. Titov & V. M. Cherkasov

Authors
  1. I. V. Boldyrev
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  2. I. F. Vladimirtsev
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  3. E. A. Romanenko
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  4. N. G. Korzhenevskaya
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  5. E. V. Titov
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  6. V. M. Cherkasov
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1248–1251, September, 1977.

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Boldyrev, I.V., Vladimirtsev, I.F., Romanenko, E.A. et al. Reaction of 5-substituted 4,6-dichloro-2-aminopyrimidines with oxalyl chloride. Chem Heterocycl Compd 13, 1006–1009 (1977). https://doi.org/10.1007/BF00472459

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  • DOI: https://doi.org/10.1007/BF00472459

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