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Mucous cells of the tracheobronchial tree in the ferret

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Summary

Mucosubstances in the tracheobronchial tree of the ferret were studied histochemically. The submucous glands contained predominantly neutral mucins. Scattered between these were cells containing sulphated mucins and sialidase-labile and sialidase-resistant sialomucins. Most of the goblet cells in the trachea, as well as those in the bronchi and large pronchioles, contained sulphated mucins. A smaller proportion of the goblet cells showed sialidase-labile and sialidase-resistant sialomucins. It will be interesting to see whether ferrets can be used to produce animal models for hypersecretory diseases such as cystic fibrosis and chronic bronchitis.

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References

  • Allen MA (1970) The effect of acid hydrolysis on sialomucins at selected epithelial sites. Thesis for the Fellowship of the Institute of Medical and Laboratory Technology, London

  • Gallagher JT, Kent PW, Passatore M, Phipps RJ, Richardson PS (1975) Composition of tracheal mucus and its secretion in the cat. Proc R Soc London 192:49–76

    Google Scholar 

  • Jacob S, Poddar S (1978) The histochemistry of mucosubstances in ferret salivary glands. Acta Histochem 615:142–154

    Google Scholar 

  • Jones R, Boldre P, Reid L (1973) Goblet cell glycoprotein and tracheal gland hypertrophy in rat airways: The effect of tobacco smoke with or without the anti-inflammatory agent phenyl methyl-oxadiazole. Br J Exp Pathol 54:229–239

    Google Scholar 

  • Jones R, Baskerville A, Reid L (1975) Histochemical identification of glycoproteins in pig bronchial epithelium. J Pathol 98:213–229

    Google Scholar 

  • Lamb D, Reid L (1968) Mitotic rates, goblet cell increase and histochemical changes in mucus in rat bronchial epithelium during exposure to sulphur dioxide. J Pathol Bact 96:97–111

    Google Scholar 

  • Lamb D, Reid L (1969) Histochemical types of acidic glycoprotein produced by mucous cells of the tracheobronchial glands in man. J Pathol 98:213–229

    Google Scholar 

  • Lamb D, Reid L (1972a) The tracheobronchial submucosal glands in cystic fibrosis. A qualitative and quantitative histochemical study. Br J Dis Chest 66:239–247

    Google Scholar 

  • Lamb D, Reid L (1972b) Quantitative distribution of various types of acid glycoprotein in mucous cells of human bronchi. Histochem J 4:91–102

    Google Scholar 

  • McCarthy C, Reid L (1964a) Acid mucopolysaccharide in the bronchial tree in the mouse and rat. Qu J Exp Physiol 49:81–84

    Google Scholar 

  • McCarthy C, Reid L (1964b) Intracellular mucopolysaccharides in the normal human bronchial tree. Qu J Exp Physiol 49:85–94

    Google Scholar 

  • McManus JFA, Mowry R (1960) Staining methods, histological and histochemical. Harper and Row, New York, pp 136–137

    Google Scholar 

  • Mowry RW (1963) The special value of methods that colour both acidic and vicinyl hydroxyl groups in the histochemical study of mucins, with revised directions for the colloidal iron stain, the use of alcian blue 8GX and their combination with the periodic acid Schiff reaction. Ann NY Acad Sci 106:402–423

    Google Scholar 

  • Murgatroyd LB (1969) Studies on histochemical demonstration of glycogen. Thesis for Fellowship of the Institute of Medical Laboratory Technology, London

  • Spicer SS (1961) The use of cationic reagents in histochemical differentiation of mucopolysaccharides. Am J Clin Pathol 36:393–407

    Google Scholar 

  • Spicer SS (1965) Diamine methods for differentiating mucopolysaccharides histochemically. J. Histochem Cytochem 13:211–234

    Google Scholar 

  • Spicer SS, Chakrin LW, Wardell JR, Kendrick W (1971) Histochemistry of mucosubstances in the canine and human respiratory tract. Lab Invest 25:483–490

    Google Scholar 

  • Spicer SS, Meyer DB (1960) Histochemical differentiation of acid mucopolysaccharides by means of combined aldehyde fuchsin-alcian blue staining. Am J Clin Pathol 33:453–460

    Google Scholar 

  • Sturgess J, Reid L (1973) The effect of isoprenaline and pilocarpine on bronchial mucus secreting tissue, pancreas, salivary glands, heart, thymus, liver and spleen. Br J Exp Pathol 54:388–403

    Google Scholar 

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Authors and Affiliations

  1. Department of Human Biology and Anatomy, University of Sheffield, S10 2TN, Sheffield, UK

    S. Jacob

  2. Department of Anatomy, University of the West Indies, Kingston, Jamaica

    S. Poddar

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  1. S. Jacob
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  2. S. Poddar
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Jacob, S., Poddar, S. Mucous cells of the tracheobronchial tree in the ferret. Histochemistry 73, 599–605 (1982). https://doi.org/10.1007/BF00493372

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  • DOI: https://doi.org/10.1007/BF00493372

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